Item Type | Name |
Concept
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Cell Plasticity
|
Concept
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Cell Self Renewal
|
Concept
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Carcinoma, Renal Cell
|
Concept
|
Cell Adhesion
|
Concept
|
Cell Cycle
|
Concept
|
Cell Differentiation
|
Concept
|
Cell Division
|
Concept
|
Cell Line
|
Concept
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Cell Membrane Permeability
|
Concept
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Cell Movement
|
Concept
|
Cell Nucleus
|
Concept
|
Dendritic Cells
|
Concept
|
Epithelial Cells
|
Concept
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HeLa Cells
|
Concept
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Neoplastic Cells, Circulating
|
Concept
|
Stem Cells
|
Concept
|
Stromal Cells
|
Concept
|
Cell Cycle Proteins
|
Concept
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Cell Culture Techniques
|
Concept
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Cell Lineage
|
Concept
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HT29 Cells
|
Concept
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Jurkat Cells
|
Concept
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Enteroendocrine Cells
|
Concept
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Paneth Cells
|
Concept
|
Stem Cell Niche
|
Concept
|
Tumor Cells, Cultured
|
Concept
|
Tumor Stem Cell Assay
|
Concept
|
Neoplastic Stem Cells
|
Concept
|
Cell Cycle Checkpoints
|
Concept
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G2 Phase Cell Cycle Checkpoints
|
Concept
|
M Phase Cell Cycle Checkpoints
|
Concept
|
Cell Growth Processes
|
Concept
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Cell Proliferation
|
Concept
|
NIH 3T3 Cells
|
Concept
|
Platelet Endothelial Cell Adhesion Molecule-1
|
Concept
|
Hep G2 Cells
|
Concept
|
Myeloid Cell Leukemia Sequence 1 Protein
|
Concept
|
HCT116 Cells
|
Concept
|
Cell Line, Tumor
|
Concept
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T-Cell Intracellular Antigen-1
|
Concept
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Cell Separation
|
Concept
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Cell Survival
|
Concept
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Cell Transformation, Neoplastic
|
Concept
|
Cells, Cultured
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Academic Article
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DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition.
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Academic Article
|
Hepatitis C virus-induced cancer stem cell-like signatures in cell culture and murine tumor xenografts.
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Academic Article
|
(Z)-3,5,4'-Trimethoxystilbene Limits Hepatitis C and Cancer Pathophysiology by Blocking Microtubule Dynamics and Cell-Cycle Progression.
|
Academic Article
|
APSA Awardee Submission: Tumor/cancer stem cell marker doublecortin-like kinase 1 in liver diseases.
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Academic Article
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XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.
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Academic Article
|
Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.
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Academic Article
|
Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells.
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Academic Article
|
Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases.
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Academic Article
|
Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury.
|
Academic Article
|
Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells.
|
Academic Article
|
Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury.
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Academic Article
|
Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis.
|
Academic Article
|
Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal.
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Academic Article
|
Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism.
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Academic Article
|
DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer.
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Academic Article
|
Brief report: Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury.
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Academic Article
|
Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism.
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Academic Article
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Inhibition of Notch signaling reduces the number of surviving Dclk1+ reserve crypt epithelial stem cells following radiation injury.
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Academic Article
|
Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical ß-catenin-dependent mechanism.
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Academic Article
|
Disruption of cyclooxygenase-1 gene results in an impaired response to radiation injury.
|
Academic Article
|
Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2.
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Academic Article
|
Cyclooxygenase expression in intestinal epithelial cells.
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Academic Article
|
Azoxymethane protects intestinal stem cells and reduces crypt epithelial mitosis through a COX-1-dependent mechanism.
|
Academic Article
|
Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes.
|
Academic Article
|
Novel intestinal splice variants of RNA-binding protein CUGBP2: isoform-specific effects on mitotic catastrophe.
|
Academic Article
|
Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2.
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Academic Article
|
CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe.
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Academic Article
|
Diphenyl difluoroketone: a curcumin derivative with potent in vivo anticancer activity.
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Academic Article
|
Dichotomous metabolism of Enterococcus faecalis induced by haematin starvation modulates colonic gene expression.
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Academic Article
|
Activation of apoptosis by 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos.
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Academic Article
|
Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis.
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Academic Article
|
Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas.
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Academic Article
|
Identification of the putative intestinal stem cell marker doublecortin and CaM kinase-like-1 in Barrett's esophagus and esophageal adenocarcinoma.
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Academic Article
|
Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism.
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Academic Article
|
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
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Academic Article
|
DCLK1 is detectable in plasma of patients with Barrett's esophagus and esophageal adenocarcinoma.
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Academic Article
|
ZIP4 silencing improves bone loss in pancreatic cancer.
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Academic Article
|
An Ethanol Extract of Hawaiian Turmeric: Extensive In Vitro Anticancer Activity Against Human Colon Cancer Cells.
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Academic Article
|
Regulation of miRNAs by agents targeting the tumor stem cell markers DCLK1, MSI1, LGR5, and BMI1.
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Academic Article
|
Cancer Stem Cell Marker DCLK1 Correlates with Tumorigenic Immune Infiltrates in the Colon and Gastric Adenocarcinoma Microenvironments.
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Academic Article
|
Tuft Cells Play Critical Roles in the Heterogeneity and Epithelial Plasticity in Pancreatic Cancer Initiation and Progression.
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Academic Article
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Tuft and Cancer Stem Cell Marker DCLK1: A New Target to Enhance Anti-Tumor Immunity in the Tumor Microenvironment.
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Academic Article
|
FGF-20: FGFs--they keep growing and growing and growing!
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Academic Article
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Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms.
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Academic Article
|
Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe.
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Academic Article
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Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo.
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Academic Article
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Enterococcus faecalis induces aneuploidy and tetraploidy in colonic epithelial cells through a bystander effect.
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Academic Article
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Loss of p21Waf1/Cip1/Sdi1 enhances intestinal stem cell survival following radiation injury.
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Academic Article
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Selective blockade of DCAMKL-1 results in tumor growth arrest by a Let-7a MicroRNA-dependent mechanism.
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Academic Article
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14-3-3sigma-dependent resistance to cisplatin.
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Academic Article
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Inhibition of angiogenesis- and inflammation-inducing factors in human colon cancer cells in vitro and in ovo by free and nanoparticle-encapsulated redox dye, DCPIP.
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Academic Article
|
Urine and serum analysis of consumed curcuminoids using an IkappaB-luciferase surrogate marker assay.
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Academic Article
|
Utility of a bacterial infection model to study epithelial-mesenchymal transition, mesenchymal-epithelial transition or tumorigenesis.
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Academic Article
|
Reg4-induced mitogenesis involves Akt-GSK3ß-ß-Catenin-TCF-4 signaling in human colorectal cancer.
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Academic Article
|
Intestinal stem cells and the colorectal cancer microenvironment.
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Academic Article
|
Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression.
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Academic Article
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Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem-like Cells Marked by DCLK1 Kinase.
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Academic Article
|
Regulatory Roles of Dclk1 in Epithelial Mesenchymal Transition and Cancer Stem Cells.
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Academic Article
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ZIP4 Promotes Muscle Wasting and Cachexia in Mice With Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells.
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Academic Article
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ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin a3ß1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells.
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Academic Article
|
A subset of epithelial cells mimics regulatory T cells and contributes to immune evasion during development of pancreatic adenocarcinoma.
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Academic Article
|
Zinc-Dependent Regulation of ZEB1 and YAP1 Coactivation Promotes Epithelial-Mesenchymal Transition Plasticity and Metastasis in Pancreatic Cancer.
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Academic Article
|
CUGBP2 plays a critical role in apoptosis of breast cancer cells in response to genotoxic injury.
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Academic Article
|
Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression.
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Academic Article
|
EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway.
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Academic Article
|
Functional antagonism between RNA binding proteins HuR and CUGBP2 determines the fate of COX-2 mRNA translation.
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Academic Article
|
Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis.
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Academic Article
|
Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively.
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Academic Article
|
DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism.
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Academic Article
|
A nomenclature for intestinal in vitro cultures.
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Academic Article
|
DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma.
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Academic Article
|
Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity.
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Academic Article
|
Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer.
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Academic Article
|
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
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Academic Article
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Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis.
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Academic Article
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DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-4.
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Academic Article
|
FGF-2 enhances intestinal stem cell survival and its expression is induced after radiation injury.
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Academic Article
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Expression of the regenerating gene family in inflammatory bowel disease mucosa: Reg Ialpha upregulation, processing, and antiapoptotic activity.
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Academic Article
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Prosurvival and antiapoptotic effects of PGE2 in radiation injury are mediated by EP2 receptor in intestine.
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Academic Article
|
Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas.
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Academic Article
|
Identification of a novel putative gastrointestinal stem cell and adenoma stem cell marker, doublecortin and CaM kinase-like-1, following radiation injury and in adenomatous polyposis coli/multiple intestinal neoplasia mice.
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Academic Article
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Cancer stem cells: a novel paradigm for cancer prevention and treatment.
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Academic Article
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RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells.
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Academic Article
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A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells.
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Academic Article
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Wnt inhibitory factor 1 suppresses cancer stemness and induces cellular senescence.
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Academic Article
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Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity.
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Academic Article
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Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis.
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Academic Article
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Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer.
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Academic Article
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DCLK1 Monoclonal Antibody-Based CAR-T Cells as a Novel Treatment Strategy against Human Colorectal Cancers.
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Academic Article
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DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization.
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Grant
|
Circulating Biomarkers for the Detection of Human Liver Diseases
|
Grant
|
The role of Dclk1 in the initiation of colorectal cancer
|
Grant
|
Targeting DCLK1 kinase activity in pancreatic cancer
|
Grant
|
PROSTAGLANDIN E2 RECEPTORS IN GASTROINTESTINAL INJURY
|
Grant
|
The role of DCLK1 in the initiation of pancreatic ductal adenocarcinoma
|
Grant
|
The Gastrointestinal Stem Cell Response to Injury
|
Grant
|
Pancreatic Stem Cells and Cancer
|
Grant
|
Isolation and Characterization of Intestinal Stem Cells Using Novel Markers (RP)
|
Grant
|
Mechanisms of tuft cell mediated regulation of the intestinal stem cell niche following injury
|
Grant
|
PROSTAGLANDINS AND GASTROINTESTINAL DNA DAMAGE
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Academic Article
|
Reg4 Interacts with CD44 to Regulate Proliferation and Stemness of Colorectal and Pancreatic Cancer Cells.
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Academic Article
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Interplay of Tumor Microenvironment Factors and Cancer Stem Cell Enrichment in Pancreatic Ductal Adenocarcinoma.
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Academic Article
|
Attenuating DNA damage response and immunosuppression radiosensitizes pancreatic cancer.
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Academic Article
|
A Novel Translational Activation of HIF1a Promotes Pancreatic Cancer Growth Through Glycolytic Reprogramming.
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Academic Article
|
Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-ß Signaling Axis in Pancreatic Cancer.
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Academic Article
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Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer.
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Academic Article
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Lysosomes Promote Cancer Metastasis via Exosome in PTEN-Deficient Tumors.
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Academic Article
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Blocking of doublecortin-like kinase 1-regulated SARS-CoV-2 replication cycle restores cell signaling network.
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Academic Article
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Epigenetic Landscape and Therapeutic Implication of Gene Isoforms of Doublecortin-Like Kinase 1 for Cancer Stem Cells.
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