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Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism.
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Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism.
Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism. J Nanobiotechnology. 2011 Sep 19; 9:40.
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PubMed
subject areas
Animals
Animals
Carcinoma
Carcinoma
Colorectal Neoplasms
Colorectal Neoplasms
Dipeptides
Dipeptides
Down-Regulation
Down-Regulation
Gene Expression Regulation, Neoplastic
Gene Expression Regulation, Neoplastic
HCT116 Cells
HCT116 Cells
Humans
Humans
Intracellular Signaling Peptides and Proteins
Intracellular Signaling Peptides and Proteins
Mice
Mice
Mice, Nude
Mice, Nude
MicroRNAs
MicroRNAs
Nanoparticles
Nanoparticles
Proto-Oncogene Proteins c-myc
Proto-Oncogene Proteins c-myc
Receptor, Notch1
Receptor, Notch1
Transcription Factors
Transcription Factors
Up-Regulation
Up-Regulation
Xenograft Model Antitumor Assays
Xenograft Model Antitumor Assays
authors with profiles
Courtney Wayne Houchen
Dongfeng Qu
Randal Joseph May