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Cook, Paul

One or more keywords matched the following items that are connected to Cook, Paul

Item Type	Name
Concept	Ammonia
Concept	Ammonia-Lyases
Concept	Ammonium Sulfate
Concept	Adenosine Triphosphate
Concept	Adult
Concept	Anions
Concept	Haplorhini
Concept	Aged
Concept	Alcaligenes
Concept	Alcohol Dehydrogenase
Concept	Alcohol Oxidoreductases
Concept	Aldehyde Oxidoreductases
Concept	Aldehyde Reductase
Concept	Algorithms
Concept	Cadmium
Concept	Protein-Arginine Deiminases
Concept	Acetates
Concept	Acetyl Coenzyme A
Concept	Acetylation
Concept	Acids
Concept	Acrylates
Concept	Carbohydrate Dehydrogenases
Concept	Amides
Concept	Amidohydrolases
Concept	Amino Acid Oxidoreductases
Concept	Amino Acid Sequence
Concept	Acyl Coenzyme A
Concept	Carbon Isotopes
Concept	Carbon Radioisotopes
Concept	Carboxy-Lyases
Concept	Carboxylic Acids
Concept	Cyclic AMP
Concept	Adenosine Deaminase
Concept	Adenosine Diphosphate
Concept	Adenosine Diphosphate Ribose
Concept	Adenosine Monophosphate
Concept	Bacillus anthracis
Concept	Bacillus subtilis
Concept	Blood Pressure
Concept	Career Mobility
Concept	Base Sequence
Concept	Borates
Concept	Cations, Divalent
Concept	Cations, Monovalent
Concept	Cattle
Concept	Benzoates
Concept	Cell Adhesion
Concept	Cell Line
Concept	Buffers
Concept	Cytosol
Concept	Decarboxylation
Concept	Computer Simulation
Concept	Computers
Concept	Biophysics
Concept	Biopsy
Concept	Biotin
Concept	Chromatography, Agarose
Concept	Chromatography, Gel
Concept	Creatine Kinase
Concept	Deuterium
Concept	Diabetes Mellitus
Concept	Crystallography
Concept	Cobalt
Concept	Cyclodextrins
Concept	Cyclohexanols
Concept	Coenzyme A
Concept	Coenzymes
Concept	Cysteine
Concept	Cysteine Synthase
Concept	Cold Temperature
Concept	Colorado
Concept	Energy Transfer
Concept	Enterobacteriaceae
Concept	Dose-Response Relationship, Drug
Concept	Drosophila melanogaster
Concept	Fibrin
Concept	Fibrinolysin
Concept	Drug Evaluation, Preclinical
Concept	Escherichia coli
Concept	Education, Nursing, Continuing
Concept	Hexokinase
Concept	Ethylmaleimide
Concept	Guanosine Triphosphate
Concept	Guinea Pigs
Concept	Haemophilus influenzae
Concept	Electron Spin Resonance Spectroscopy
Concept	Electron Transport
Concept	Horses
Concept	Health Facility Environment
Concept	Health Maintenance Organizations
Concept	Humans
Concept	Hydro-Lyases
Concept	Hydrogen
Concept	Hydrogen Bonding
Concept	Genes, Bacterial
Concept	Genes, Fungal
Concept	Gluconates
Concept	Glucosephosphate Dehydrogenase
Concept	Liver
Concept	Oxo-Acid-Lyases
Concept	Ketoglutaric Acids
Concept	Glucose-6-Phosphate Isomerase
Concept	Glucuronates
Concept	Glutamate Dehydrogenase
Concept	Glutamates
Concept	Glutamine
Concept	Glutathione
Concept	Glutathione Transferase
Concept	Glycerolphosphate Dehydrogenase
Concept	Glycoside Hydrolases
Concept	Lysine
Concept	Glycosylation
Concept	Glyoxylates
Concept	L-Lactate Dehydrogenase
Concept	Magnesium
Concept	Malate Dehydrogenase
Concept	Malates
Concept	Maleates
Concept	Malonates
Concept	Mandelic Acids
Concept	Manganese
Concept	Inosine Triphosphate
Concept	Fabaceae
Concept	Niacinamide
Concept	Muscles
Concept	Nitrobenzenes
Concept	Nitrobenzoates
Concept	Nitrogen Isotopes
Concept	Intestinal Mucosa
Concept	Myocardium
Concept	Norleucine
Concept	NAD
Concept	NADP
Concept	Nucleoside Deaminases
Concept	Iron
Concept	Naphthols
Concept	Nucleotides
Concept	Isocitrate Dehydrogenase
Concept	Isocitrates
Concept	Isoelectric Point
Concept	Isomerism
Concept	Nursing Staff
Concept	Job Satisfaction
Concept	Plants
Concept	Plants, Medicinal
Concept	Plasminogen
Concept	Poly Adenosine Diphosphate Ribose
Concept	Poly(ADP-ribose) Polymerases
Concept	Middle Aged
Concept	Phenylalanine
Concept	Mitochondria
Concept	Models, Structural
Concept	Phosphates
Concept	Phosphoadenosine Phosphosulfate
Concept	Phosphocreatine
Concept	Phosphofructokinase-1
Concept	Phosphogluconate Dehydrogenase
Concept	Potassium
Concept	Potassium Chloride
Concept	Molecular Sequence Data
Concept	Phosphoric Monoester Hydrolases
Concept	Phosphopeptides
Concept	Phosphoric Acids
Concept	Phosphorus Isotopes
Concept	Phosphorus Radioisotopes
Concept	Phosphorylation
Concept	Phosphotransferases
Concept	Motivation
Concept	Phylogeny
Concept	Precipitin Tests
Concept	Pregnancy
Concept	Pichia
Concept	Columbidae
Concept	Piperidones
Concept	Saccharomyces cerevisiae
Concept	Saccharopine Dehydrogenases
Concept	Salaries and Fringe Benefits
Concept	Regression Analysis
Concept	Salmonella typhimurium
Concept	Patient Education as Topic
Concept	Retrospective Studies
Concept	L-Serine Dehydratase
Concept	Peptide Fragments
Concept	Peptides
Concept	Risk Factors
Concept	Sheep
Concept	Periodicals as Topic
Concept	Thymus Gland
Concept	Swine
Concept	Pyridoxal
Concept	Pyridoxal Phosphate
Concept	Pyridoxamine
Concept	Diphosphates
Concept	Pyruvates
Concept	Tartrates
Concept	Tartronates
Concept	Rabbits
Concept	Temperature
Concept	Program Evaluation
Concept	Thiadiazoles
Concept	Thiocyanates
Concept	Nursing Evaluation Research
Concept	Nursing Methodology Research
Concept	Zinc
Concept	2-Aminoadipic Acid
Concept	2,6-Dichloroindophenol
Concept	HIV Infections
Concept	Blotting, Western
Concept	Restriction Mapping
Concept	Drug Design
Concept	Stereoisomerism
Concept	Ascaris suum
Concept	Structure-Activity Relationship
Concept	Molecular Probes
Concept	Students, Nursing
Concept	Subcellular Fractions
Concept	Genes, Helminth
Concept	Succinates
Concept	Sugar Alcohol Dehydrogenases
Concept	Sulfates
Concept	Sulfides
Concept	Sulfonamides
Concept	Sulfur
Concept	Glycosylphosphatidylinositols
Concept	Point Mutation
Concept	Arabidopsis
Concept	Sequence Homology, Amino Acid
Concept	Pseudomonas putida
Concept	Protein Structure, Secondary
Concept	Protein Structure, Tertiary
Concept	Patient Satisfaction
Concept	Vitamin K
Concept	Risk Assessment
Concept	Mutagenesis, Site-Directed
Concept	Frail Elderly
Concept	Open Reading Frames
Concept	Glutamic Acid
Concept	GTP-Binding Proteins
Concept	Acrylamide
Concept	Mutation, Missense
Concept	Catalytic Domain
Concept	Hyphomicrobium
Concept	Leukotriene C4
Concept	Combinatorial Chemistry Techniques
Concept	Protein Renaturation
Concept	Glucuronic Acid
Concept	Crystallography, X-Ray
Concept	Phenol
Concept	Succinic Acid
Concept	Sodium Azide
Concept	Hydroxylamine
Concept	Amino Acid Substitution
Concept	Probability
Concept	Dihydrouracil Dehydrogenase (NADP)
Concept	Proline
Concept	Propionibacterium
Concept	Nurse's Role
Concept	Drug Resistance, Bacterial
Concept	Phosphofructokinases
Concept	Protein Denaturation
Concept	Protein Kinases
Concept	Transglutaminases
Concept	Phosphofructokinase-2
Concept	Protons
Concept	Pseudomonas
Concept	Carboxypeptidase B2
Concept	Pterins
Concept	Electron-Transferring Flavoproteins
Concept	2-Aminoadipate Transaminase
Concept	Mice
Concept	Rats
Concept	Sodium
Concept	Sodium Chloride
Concept	Software
Concept	Spectrometry, Fluorescence
Concept	Tricarboxylic Acids
Concept	Triose-Phosphate Isomerase
Concept	Tritium
Concept	Tryptophan Synthase
Concept	Uracil
Concept	Quality Improvement
Concept	Gene Expression
Concept	Comorbidity
Concept	Logistic Models
Concept	Case-Control Studies
Concept	Mutagenesis, Insertional
Concept	alpha-Cyclodextrins
Concept	Intracellular Signaling Peptides and Proteins
Concept	Total Quality Management
Concept	Phosphotransferases (Alcohol Group Acceptor)
Concept	Cyclic AMP-Dependent Protein Kinases
Concept	NIH 3T3 Cells
Concept	DNA Primers
Concept	Dimerization
Concept	Pyruvic Acid
Concept	Computational Biology
Concept	Alanine Dehydrogenase
Concept	Mitogen-Activated Protein Kinases
Concept	Oxaloacetic Acid
Concept	Organic Chemistry Phenomena
Concept	Young Adult
Concept	ortho-Aminobenzoates
Concept	Smoking Prevention
Concept	Apoenzymes
Concept	Arginine
Concept	Ascaris
Concept	Asparagine
Concept	Aspartate Aminotransferases
Concept	Aspartate Ammonia-Lyase
Concept	Aspartic Acid
Concept	Cell Wall
Concept	Cells, Cultured
Concept	Chickens
Concept	Chlorides
Concept	Diacetyl
Concept	Diamines
Concept	Diazooxonorleucine
Concept	Dictyostelium
Concept	Diethyl Pyrocarbonate
Concept	Dihydroorotase
Concept	Dihydropteroate Synthase
Concept	Dimethylformamide
Concept	Dipeptidases
Concept	Disulfides
Concept	Dithionitrobenzoic Acid
Concept	Flavins
Concept	Fluorescence
Concept	Fluorescence Polarization
Concept	Fluorometry
Concept	Formate Dehydrogenases
Concept	Formates
Concept	Fructose-Bisphosphate Aldolase
Concept	Fumarate Hydratase
Concept	Fumarates
Concept	gamma-Glutamyltransferase
Concept	Indoles
Concept	Mass Screening
Concept	Metals, Rare Earth
Concept	Methionine
Concept	Oligopeptides
Concept	Oncology Nursing
Concept	Osmosis
Concept	Oxalates
Concept	Oxaloacetates
Concept	Oxidation-Reduction
Concept	Oxygen
Concept	Oxygen Isotopes
Concept	4-Aminobenzoic Acid
Academic Article	Glutamate 325 is a general acid-base catalyst in the reaction catalyzed by fructose-2,6-bisphosphatase.
Academic Article	Pyridoxal 5'-phosphate-dependent alpha,beta-elimination reactions: mechanism of O-acetylserine sulfhydrylase.
Academic Article	Dihydropyrimidine amidohydrolases and dihydroorotases share the same origin and several enzymatic properties.
Academic Article	Expression of transglutaminase substrate activity on Candida albicans germ tubes through a coiled, disulfide-bonded N-terminal domain of Hwp1 requires C-terminal glycosylphosphatidylinositol modification.
Academic Article	Kinetic analysis of YPD1-dependent phosphotransfer reactions in the yeast osmoregulatory phosphorelay system.
Academic Article	Purification and properties of beta-alanine synthase from calf liver.
Academic Article	A three-dimensional homology model of the O-acetylserine sulfhydrylase-B from Salmonella typhimurium.
Academic Article	Optimum activity of the phosphofructokinase from Ascaris suum requires more than one metal ion.
Academic Article	Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae.
Academic Article	Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Role of the S128, H186, and N187 triad in substrate binding and decarboxylation in the sheep liver 6-phosphogluconate dehydrogenase reaction.
Academic Article	Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes.
Academic Article	Proper positioning of the nicotinamide ring is crucial for the Ascaris suum malic enzyme reaction.
Academic Article	Effect of mutation of lysine-120, located at the entry to the active site of O-acetylserine sulfhydrylase-A from Salmonella typhimurium.
Academic Article	Role of Histidine-152 in cofactor orientation in the PLP-dependent O-acetylserine sulfhydrylase reaction.
Academic Article	Chemical mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Examination of intrinsic sulfonamide resistance in Bacillus anthracis: a novel assay for dihydropteroate synthase.
Academic Article	Potassium is an activator of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Isotope exchange at equilibrium indicates a steady state ordered kinetic mechanism for human sulfotransferase.
Academic Article	Evaluation of a career ladder program in an ambulatory care environment.
Academic Article	Design of O-acetylserine sulfhydrylase inhibitors by mimicking nature.
Academic Article	Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.
Academic Article	Reaction product affinity regulates activation of human sulfotransferase 1A1 PAP sulfation.
Academic Article	Kinetics of activated thrombin-activatable fibrinolysis inhibitor (TAFIa)-catalyzed cleavage of C-terminal lysine residues of fibrin degradation products and removal of plasminogen-binding sites.
Academic Article	The multifaceted pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase.
Academic Article	Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Utility of the theory of planned behavior to predict nursing staff blood pressure monitoring behaviours.
Academic Article	Evidence for an induced conformational change in the catalytic mechanism of homoisocitrate dehydrogenase for Saccharomyces cerevisiae: Characterization of the D271N mutant enzyme.
Academic Article	Probing the chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae using site-directed mutagenesis.
Academic Article	Kinetic mechanism of the adenosine 3',5'-monophosphate dependent protein kinase catalytic subunit in the direction of magnesium adenosine 5'-diphosphate phosphorylation.
Academic Article	Mechanism of activation of the NAD-malic enzyme from Ascaris suum by fumarate.
Academic Article	pH dependence of the absorbance and 31P NMR spectra of O-acetylserine sulfhydrylase in the absence and presence of O-acetyl-L-serine.
Academic Article	pH dependence of the kinetic parameters for the pyrophosphate-dependent phosphofructokinase reaction supports a proton-shuttle mechanism.
Academic Article	Substrate activation by malate induced by oxalate in the Ascaris suum NAD-malic enzyme reaction.
Academic Article	Chemical mechanism of the adenosine cyclic 3',5'-monophosphate dependent protein kinase from pH studies.
Academic Article	Inactivation of pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii by pyridoxal 5'-phosphate. Determination of the pH dependence of enzyme-reactant dissociation constants from protection against inactivation.
Academic Article	Isotope exchange as a probe of the kinetic mechanism of pyrophosphate-dependent phosphofructokinase.
Academic Article	Kinetic mechanism of pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii.
Academic Article	Kinetic studies to determine the mechanism of regulation of bovine liver glutamate dehydrogenase by nucleotide effectors.
Academic Article	Acid-base chemical mechanism of aspartase from Hafnia alvei.
Academic Article	Acid-base catalytic mechanism and pH dependence of fructose 2,6-bisphosphate activation of the Ascaris suum phosphofructokinase.
Academic Article	Kinetic isotope effects as a probe of the beta-elimination reaction catalyzed by O-acetylserine sulfhydrylase.
Academic Article	Tryptophan luminescence as a probe of enzyme conformation along the O-acetylserine sulfhydrylase reaction pathway.
Academic Article	Comparison of the substrate specificities of cAMP-dependent protein kinase from bovine heart and Ascaris suum muscle.
Academic Article	Time-resolved fluorescence of O-acetylserine sulfhydrylase catalytic intermediates.
Academic Article	Ligand binding induces a large conformational change in O-acetylserine sulfhydrylase from Salmonella typhimurium.
Academic Article	Lysine 183 is the general base in the 6-phosphogluconate dehydrogenase-catalyzed reaction.
Academic Article	Substitution of pyridoxal 5'-phosphate in D-serine dehydratase from Escherichia coli by cofactor analogues provides information on cofactor binding and catalysis.
Academic Article	Initial velocity, spectral, and pH studies of the serine-glyoxylate aminotransferase from Hyphomicrobiuim methylovorum.
Academic Article	Characterization of the allosteric anion-binding site of O-acetylserine sulfhydrylase.
Academic Article	Crystal structure of the malic enzyme from Ascaris suum complexed with nicotinamide adenine dinucleotide at 2.3 A resolution.
Academic Article	Alpha,beta-elimination reaction of O-acetylserine sulfhydrylase. Is the pyridine ring required?
Academic Article	Surface-exposed tryptophan residues are essential for O-acetylserine sulfhydrylase structure, function, and stability.
Academic Article	Kinetic mechanism of the serine acetyltransferase from Haemophilus influenzae.
Academic Article	Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae.
Academic Article	Role of methionine-13 in the catalytic mechanism of 6-phosphogluconate dehydrogenase from sheep liver.
Academic Article	A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme.
Academic Article	Mechanism of the addition half of the O-acetylserine sulfhydrylase-A reaction.
Academic Article	Bisubstrate inhibition: Theory and application to N-acetyltransferases.
Academic Article	A proposed proton shuttle mechanism for saccharopine dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Complete kinetic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Overall kinetic mechanism of saccharopine dehydrogenase (L-glutamate forming) from Saccharomyces cerevisiae.
Academic Article	Chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae.
Academic Article	(31)P NMR studies of O-acetylserine sulfhydrylase-B from Salmonella typhimurium.
Academic Article	Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4): evidence that general acid catalysis promotes efficient inactivation.
Academic Article	Identification of the structural determinants for the stability of substrate and aminoacrylate external Schiff bases in O-acetylserine sulfhydrylase-A.
Academic Article	Mechanism of the aromatic aminotransferase encoded by the Aro8 gene from Saccharomyces cerevisiae.
Academic Article	Inhibition of human ?-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors.
Academic Article	Isozyme-specific ligands for O-acetylserine sulfhydrylase, a novel antibiotic target.
Academic Article	Mechanism of O-acetylserine sulfhydrylase fromSalmonella typhimurium LT-2.
Academic Article	Crystallization of the NAD-dependent malic enzyme from the parasitic nematode Ascaris suum.
Academic Article	Effector-induced conformational transitions in Ascaris suum phosphofructokinase. A fluorescence and circular dichroism study.
Academic Article	Fructose 2,6-bisphosphate and AMP increase the affinity of the Ascaris suum phosphofructokinase for fructose 6-phosphate in a process separate from the relief of ATP inhibition.
Academic Article	Correlation between hysteresis and allosteric properties for phosphofructokinase from Ascaris suum.
Academic Article	Reaction of Ascaris suum phosphofructokinase with diethylpyrocarbonate. Inactivation and desensitization to allosteric modulation.
Academic Article	Kinetic mechanism of Ascaris suum phosphofructokinase desensitized to allosteric modulation by diethylpyrocarbonate modification.
Academic Article	Carbohydrate substrate specificity of bacterial and plant pyrophosphate-dependent phosphofructokinases.
Academic Article	Kinetic studies on the activation of pyrophosphate-dependent phosphofructokinase from mung bean by fructose 2,6-bisphosphate and related compounds.
Academic Article	Isotope partitioning in the adenosine 3',5'-monophosphate dependent protein kinase reaction indicates a steady-state random kinetic mechanism.
Academic Article	The kinetic mechanism of human placental aldose reductase and aldehyde reductase II.
Academic Article	Use of primary deuterium and 15N isotope effects to deduce the relative rates of steps in the mechanisms of alanine and glutamate dehydrogenases.
Academic Article	Adenosine cyclic 3',5'-monophosphate dependent protein kinase: kinetic mechanism for the bovine skeletal muscle catalytic subunit.
Academic Article	Solvent isotope effects on the reaction catalyzed by yeast hexokinase.
Academic Article	pH studies toward the elucidation of the auxiliary catalyst for pig heart aspartate aminotransferase.
Academic Article	Kinetic mechanism and location of rate-determining steps for aspartase from Hafnia alvei.
Academic Article	Kinetic mechanism in the direction of oxidative decarboxylation for NAD-malic enzyme from Ascaris suum.
Academic Article	Determination of dissociation constants for enzyme-reactant complexes for NAD-malic enzyme by modulation of the thiol inactivation rate.
Academic Article	Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase.
Academic Article	Metal ion activator effects on intrinsic isotope effects for hydride transfer from decarboxylation in the reaction catalyzed by the NAD-malic enzyme from Ascaris suum.
Academic Article	Substitution of pyridoxal 5'-phosphate in the O-acetylserine sulfhydrylase from Salmonella typhimurium by cofactor analogs provides a test of the mechanism proposed for formation of the alpha-aminoacrylate intermediate.
Academic Article	Secondary tritium and solvent deuterium isotope effects as a probe of the reaction catalyzed by porcine recombinant dihydropyrimidine dehydrogenase.
Academic Article	Cloning, expression, purification, and characterization of the 6-phosphogluconate dehydrogenase from sheep liver.
Academic Article	Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
Academic Article	Oxidative decarboxylation of 6-phosphogluconate by 6-phosphogluconate dehydrogenase proceeds by a stepwise mechanism with NADP and APADP as oxidants.
Academic Article	Expression and stereochemical and isotope effect studies of active 4-oxalocrotonate decarboxylase.
Academic Article	O-acetylserine sulfhydrylase.
Academic Article	Tartrate dehydrogenase catalyzes the stepwise oxidative decarboxylation of D-malate with both NAD and thio-NAD.
Academic Article	Alternative substrates for malic enzyme: oxidative decarboxylation of L-aspartate.
Academic Article	Kinetic mechanism of NAD:malic enzyme from Ascaris suum in the direction of reductive carboxylation.
Academic Article	Crystallographic studies on Ascaris suum NAD-malic enzyme bound to reduced cofactor and identification of an effector site.
Academic Article	Ascaris suum NAD-malic enzyme is activated by L-malate and fumarate binding to separate allosteric sites.
Academic Article	Stabilization and characterization of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae.
Academic Article	Structure and mechanism of O-acetylserine sulfhydrylase.
Academic Article	Dihydropyrimidine dehydrogenase: a flavoprotein with four iron-sulfur clusters.
Academic Article	Multiple isotope effects with alternative dinucleotide substrates as a probe of the malic enzyme reaction.
Academic Article	Modification of a thiol at the active site of the Ascaris suum NAD-malic enzyme results in changes in the rate-determining steps for oxidative decarboxylation of L-malate.
Academic Article	Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. II. Theory.
Academic Article	Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. I. Kinetic studies.
Academic Article	Reaction of serine-glyoxylate aminotransferase with the alternative substrate ketomalonate indicates rate-limiting protonation of a quinonoid intermediate.
Academic Article	Importance in catalysis of the 6-phosphate-binding site of 6-phosphogluconate in sheep liver 6-phosphogluconate dehydrogenase.
Academic Article	An isothermal titration calorimetry study of the binding of substrates and ligands to the tartrate dehydrogenase from Pseudomonas putida reveals half-of-the-sites reactivity.
Academic Article	A rapid purification procedure and computer-assisted sulfide ion selective electrode assay for O-acetylserine sulfhydrylase from Salmonella typhimurium.
Academic Article	Isotope partitioning for NAD-malic enzyme from Ascaris suum confirms a steady-state random kinetic mechanism.
Academic Article	Control of ionizable residues in the catalytic mechanism of tryptophan synthase from Salmonella typhimurium.
Academic Article	Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae.
Academic Article	The relationship between glycemic control and falls in older adults.
Academic Article	Roles of histidines 154 and 189 and aspartate 139 in the active site of serine acetyltransferase from Haemophilus influenzae.
Academic Article	Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae.
Academic Article	Molecular basis for the isozymes of bovine glucose-6-phosphate isomerase.
Academic Article	Kinetics and mechanism of benzoylformate decarboxylase using 13C and solvent deuterium isotope effects on benzoylformate and benzoylformate analogues.
Academic Article	Effects of osmolytes on the SLN1-YPD1-SSK1 phosphorelay system from Saccharomyces cerevisiae.
Academic Article	A two-step process controls the formation of the bienzyme cysteine synthase complex.
Academic Article	Evidence from nitrogen-15 and solvent deuterium isotope effects on the chemical mechanism of adenosine deaminase.
Academic Article	Evaluation of a patient navigation program.
Academic Article	Protonation mechanism and location of rate-determining steps for the Ascaris suum nicotinamide adenine dinucleotide-malic enzyme reaction from isotope effects and pH studies.
Academic Article	Kinetic and chemical mechanisms of homocitrate synthase from Thermus thermophilus.
Academic Article	Mechanism from isotope effects.
Academic Article	Modification of an arginine residue essential for the activity of NAD-malic enzyme from Ascaris suum.
Academic Article	Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.
Academic Article	Fine tuning of the active site modulates specificity in the interaction of O-acetylserine sulfhydrylase isozymes with serine acetyltransferase.
Academic Article	The evolution of a doctor of nursing practice capstone process: programmatic revisions to improve the quality of student projects.
Academic Article	Primary and secondary deuterium isotope effects on equilibrium constants for enzyme-catalyzed reactions.
Academic Article	Use of pH studies to elucidate the catalytic mechanism of rabbit muscle creatine kinase.
Academic Article	Mechanistic deductions from isotope effects in multireactant enzyme mechanisms.
Academic Article	pH variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same.
Academic Article	pH variation of isotope effects in enzyme-catalyzed reactions. 2. Isotope-dependent step not pH dependent. Kinetic mechanism of alcohol dehydrogenase.
Academic Article	Secondary deuterium and nitrogen-15 isotope effects in enzyme-catalyzed reactions. Chemical mechanism of liver alcohol dehydrogenase.
Academic Article	Lanthanide pyrophosphates as substrates for the pyrophosphate-dependent phosphofructokinases from Propionibacterium freudenreichii and Phaseolus aureus: evidence for a second metal ion required for reaction.
Academic Article	Product binding to the alpha-carboxyl subsite results in a conformational change at the active site of O-acetylserine sulfhydrylase-A: evidence from fluorescence spectroscopy.
Academic Article	Stepwise versus concerted oxidative decarboxylation catalyzed by malic enzyme: a reinvestigation.
Academic Article	Kinetic mechanism of serine transacetylase from Salmonella typhimurium.
Academic Article	pH dependence of the kinetic mechanism of the adenosine 3',5'-monophosphate dependent protein kinase catalytic subunit in the direction of magnesium adenosine 5'-diphosphate phosphorylation.
Academic Article	Kinetic and chemical mechanisms of the sheep liver 6-phosphogluconate dehydrogenase.
Academic Article	Three-dimensional structure of O-acetylserine sulfhydrylase from Salmonella typhimurium.
Academic Article	Catalytic competence of O-acetylserine sulfhydrylase in the crystal probed by polarized absorption microspectrophotometry.
Academic Article	Glutamate 190 is a general acid catalyst in the 6-phosphogluconate-dehydrogenase-catalyzed reaction.
Academic Article	Multiple isotope effects as a probe of proton and hydride transfer in the 6-phosphogluconate dehydrogenase reaction.
Academic Article	Reaction mechanism of fructose-2,6-bisphosphatase. A mutation of nucleophilic catalyst, histidine 256, induces an alteration in the reaction pathway.
Academic Article	Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities.
Academic Article	Lysine 199 is the general acid in the NAD-malic enzyme reaction.
Academic Article	Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: structure of the enzyme with chloride bound.
Academic Article	Detection of intermediates in reactions catalyzed by PLP-dependent enzymes: O-acetylserine sulfhydrylase and serine-glyoxalate aminotransferase.
Academic Article	Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
Academic Article	Chemical mechanism of the serine acetyltransferase from Haemophilus influenzae.
Academic Article	The serine acetyltransferase reaction: acetyl transfer from an acylpantothenyl donor to an alcohol.
Academic Article	Interaction of serine acetyltransferase with O-acetylserine sulfhydrylase active site: evidence from fluorescence spectroscopy.
Academic Article	Crystal structure of the his-tagged saccharopine reductase from Saccharomyces cerevisiae at 1.7-A resolution.
Academic Article	The alpha-aminoadipate pathway for lysine biosynthesis in fungi.
Academic Article	The 2'-phosphate of NADP is responsible for proper orientation of the nicotinamide ring in the oxidative decarboxylation reaction catalyzed by sheep liver 6-phosphogluconate dehydrogenase.
Academic Article	Multiple roles of arginine 181 in binding and catalysis in the NAD-malic enzyme from Ascaris suum.
Academic Article	Proper orientation of the nicotinamide ring of NADP is important for the precatalytic conformational change in the 6-phosphogluconate dehydrogenase reaction.
Academic Article	Role of residues in the adenosine binding site of NAD of the Ascaris suum malic enzyme.
Academic Article	A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase.
Academic Article	Detection of a gem-diamine and a stable quinonoid intermediate in the reaction catalyzed by serine-glyoxylate aminotransferase from Hyphomicrobium methylovorum.
Academic Article	A lysine-tyrosine pair carries out acid-base chemistry in the metal ion-dependent pyridine dinucleotide-linked beta-hydroxyacid oxidative decarboxylases.
Academic Article	Introduction to the special issue. Foreword.
Academic Article	para-Nitrophenyl sulfate activation of human sulfotransferase 1A1 is consistent with intercepting the E[middle dot]PAP complex and reformation of E[middle dot]PAPS.
Academic Article	Exploring O-acetylserine sulfhydrylase-B isoenzyme from Salmonella typhimurium by fluorescence spectroscopy.
Academic Article	Kinetic studies of the yeast His-Asp phosphorelay signaling pathway.
Academic Article	(31)P NMR spectroscopy senses the microenvironment of the 5'-phosphate group of enzyme-bound pyridoxal 5'-phosphate.
Academic Article	Gamma-glutamyl compounds: substrate specificity of gamma-glutamyl transpeptidase enzymes.
Academic Article	Cardiovascular risk assessment for persons living with HIV.
Academic Article	The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH.
Academic Article	Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction.
Academic Article	Divergent effects of compounds on the hydrolysis and transpeptidation reactions of ?-glutamyl transpeptidase.
Academic Article	Structure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation.
Academic Article	Stereoselective preparation of deuterated reduced nicotinamide adenine nucleotides and substrates by enzymatic synthesis.
Academic Article	salmonella typhimurium/enzymol.
Academic Article	Cysteine synthetase from Salmonella typhimurium LT-2. Aggregation, kinetic behavior, and effect of modifiers.
Academic Article	A reaction mechanism from steady state kinetic studies for O-acetylserine sulfhydrylase from Salmonella typhimurium LT-2.
Academic Article	Overall mechanism and rate equation for O-acetylserine sulfhydrylase.
Academic Article	Kinetic mechanism of dihydropyrimidine dehydrogenase from pig liver.
Academic Article	pH dependence of kinetic parameters for oxalacetate decarboxylation and pyruvate reduction reactions catalyzed by malic enzyme.
Academic Article	The pH dependence of the reductive carboxylation of pyruvate by malic enzyme.
Academic Article	Diethylpyrocarbonate inactivation of NAD-malic enzyme from Ascaris suum.
Academic Article	Equilibrium model in an in vitro poly(ADP-ribose) turnover system.
Academic Article	Identification and spectral characterization of the external aldimine of the O-acetylserine sulfhydrylase reaction.
Academic Article	Acid-base chemical mechanism of O-acetylserine sulfhydrylases-A and -B from pH studies.
Academic Article	A pH-dependent allosteric transition in Ascaris suum phosphofructokinase distinct from that observed with fructose 2,6-bisphosphate.
Academic Article	The 2'-phosphate of NADP is critical for optimum productive binding to 6-phosphogluconate dehydrogenase from Candida utilis.
Academic Article	Cloning and nucleotide sequence of a full-length cDNA encoding Ascaris suum malic enzyme.
Academic Article	Acid base catalytic mechanism of the dihydropyrimidine dehydrogenase from pH studies.
Academic Article	Product dependence of deuterium isotope effects in enzyme-catalyzed reactions.
Academic Article	Overall kinetic mechanism of 6-phosphogluconate dehydrogenase from Candida utilis.
Academic Article	Chemical mechanism of 6-phosphogluconate dehydrogenase from Candida utilis from pH studies.
Academic Article	Crystallization and preliminary X-ray data for the A-isozyme of O-acetylserine sulfhydrylase from Salmonella typhimurium.
Academic Article	Kinetic mechanisms of the A and B isozymes of O-acetylserine sulfhydrylase from Salmonella typhimurium LT-2 using the natural and alternative reactants.
Academic Article	Chemical mechanism of the fructose-6-phosphate,2-kinase reaction from the pH dependence of kinetic parameters of site-directed mutants of active site basic residues.
Grant	STRUCTURE AND MECHANISM OF NAD-MALIC ENZYME
Grant	STRUCTURE/MECHANISM OF 6-PHOSPHOGLUCONATE DEHYDROGENASE

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