Item Type | Name |
Concept
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Animals
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Concept
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Animal Feed
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Concept
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Animal Nutritional Physiological Phenomena
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Concept
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Behavior, Animal
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Concept
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Mammary Glands, Animal
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Concept
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Sexual Behavior, Animal
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Concept
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Models, Animal
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Concept
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Disease Models, Animal
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Grant
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Targeting the Metabolic Basis of Cachexia in Pancreatic Cancer
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Academic Article
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3JC48-3 (methyl 4'-methyl-5-(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)-[1,1'-biphenyl]-3-carboxylate): a novel MYC/MAX dimerization inhibitor reduces prostate cancer growth.
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Academic Article
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Design and development of Amphotericin B bearing polycaprolactone microparticles for macrophage targeting.
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Academic Article
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Analyzing FDA-approved drugs for compliance of pharmacokinetic principles: should there be a critical screening parameter in drug designing protocols?
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Academic Article
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Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins.
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Academic Article
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Lafora disease E3 ubiquitin ligase malin is recruited to the processing bodies and regulates the microRNA-mediated gene silencing process via the decapping enzyme Dcp1a.
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Academic Article
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Pyrazoloquinazolines: Synthetic strategies and bioactivities.
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Academic Article
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Immunotherapeutic vitamin E nanoemulsion synergies the antiproliferative activity of paclitaxel in breast cancer cells via modulating Th1 and Th2 immune response.
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Academic Article
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Combination of mAb-AR20.5, anti-PD-L1 and PolyICLC inhibits tumor progression and prolongs survival of MUC1.Tg mice challenged with pancreatic tumors.
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Academic Article
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Pluronic block copolymers enhance the anti-myeloma activity of proteasome inhibitors.
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Academic Article
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a-Tocopherol succinate protects mice against radiation-induced gastrointestinal injury.
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Academic Article
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EHD1 and RUSC2 Control Basal Epidermal Growth Factor Receptor Cell Surface Expression and Recycling.
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Academic Article
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Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease.
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Academic Article
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An update on small molecule strategies targeting leishmaniasis.
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Academic Article
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Expression of GPI anchored human recombinant erythropoietin in CHO cells is devoid of glycosylation heterogeneity.
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Academic Article
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Design and development of PEGylated liposomal formulation of HER2 blocker Lapatinib for enhanced anticancer activity and diminished cardiotoxicity.
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Academic Article
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Listeria monocytogenes upregulates mitochondrial calcium signalling to inhibit LC3-associated phagocytosis as a survival strategy.
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Academic Article
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Chitosan coated PluronicF127 micelles for effective delivery of Amphotericin B in experimental visceral leishmaniasis.
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Academic Article
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An efficient method for extracting next-generation sequencing quality RNA from liver tissue of recalcitrant animal species.
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Academic Article
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RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells.
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Academic Article
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Bridging small interfering RNA with giant therapeutic outcomes using nanometric liposomes.
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Academic Article
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Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance.
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Academic Article
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Radioprotective efficacy of tocopherol succinate is mediated through granulocyte-colony stimulating factor.
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Academic Article
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MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer.
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Academic Article
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Immune gene expression in swine macrophages expressing the Torque Teno Sus Virus1 (TTSuV1) ORF-1 and 2 proteins.
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Academic Article
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Investigation of indole functionalized pyrazoles and oxadiazoles as anti-inflammatory agents: Synthesis, in-vivo, in-vitro and in-silico analysis.
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Academic Article
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Temporal analysis of melanogenesis identifies fatty acid metabolism as key skin pigment regulator.
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Academic Article
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Deletion of the CTRL2 Insulator in HSV-1 Results in the Decreased Expression of Genes Involved in Axonal Transport and Attenuates Reactivation In Vivo.
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Academic Article
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Local and systemic immunosuppression in pancreatic cancer: Targeting the stalwarts in tumor's arsenal.
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Academic Article
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Targeting Hypoxia-Inducible Factor-1a/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis.
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Academic Article
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Histone deacetylase: A potential therapeutic target for ovarian dysfunction.
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Academic Article
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MUC1-Mediated Metabolic Alterations Regulate Response to Radiotherapy in Pancreatic Cancer.
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Academic Article
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Macrophages potentiate STAT3 signaling in skeletal muscles and regulate pancreatic cancer cachexia.
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Academic Article
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Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression.
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Academic Article
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Cyclodextrin based bone regenerative inclusion complex for resveratrol in postmenopausal osteoporosis.
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Academic Article
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Nutritional and physiological responses of broiler chicken to the dietary supplementation of Moringa oleifera aqueous leaf extract and ascorbic acid in tropics.
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Academic Article
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A molecular insight of inflammatory cascades in rheumatoid arthritis and anti-arthritic potential of phytoconstituents.
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Academic Article
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Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin.
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Academic Article
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An exhaustive compilation on chemistry of triazolopyrimidine: A journey through decades.
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Academic Article
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Preparedness for malaria elimination in the wake of climate change in the State of Uttarakhand (India).
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Academic Article
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CXC chemokine receptor 4 (CXCR4) targeted gold nanoparticles potently enhance radiotherapy outcomes in breast cancer.
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Academic Article
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A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species.
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Academic Article
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Protein and peptide delivery to lungs by using advanced targeted drug delivery.
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Academic Article
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Alpha-tocopherol succinate-mobilized progenitors improve intestinal integrity after whole body irradiation.
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Academic Article
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Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
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Academic Article
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a-Tocopherol succinate- and AMD3100-mobilized progenitors mitigate radiation-induced gastrointestinal injury in mice.
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Academic Article
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Pluronic F-127 Stabilised Docetaxel Nanocrystals Improve Apoptosis by Mitochondrial Depolarization in Breast Cancer Cells: Pharmacokinetics and Toxicity Assessment.
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Academic Article
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Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth.
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Academic Article
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The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.
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Academic Article
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Hypoxia-Mediated In Vivo Tumor Glucose Uptake Measurement and Analysis.
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Academic Article
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Evaluation of Macrophage Polarization in Pancreatic Cancer Microenvironment Under Hypoxia.
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Academic Article
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Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.
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Academic Article
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Radioprotective properties of tocopherol succinate against ionizing radiation in mice.
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Academic Article
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Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2.
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Academic Article
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JNK signaling contributes to skeletal muscle wasting and protein turnover in pancreatic cancer cachexia.
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Academic Article
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IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer.
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Academic Article
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A study on dengue outbreak during 2009 in Bhopal and Indore districts of Madhya Pradesh, India.
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Academic Article
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Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism.
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Academic Article
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Role of radiation-induced granulocyte colony-stimulating factor in recovery from whole body gamma-irradiation.
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Academic Article
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Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects.
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Academic Article
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Herpes Simplex Virus 1 MicroRNA miR-H8 Is Dispensable for Latency and Reactivation In Vivo.
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Academic Article
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Mobilized progenitor cells as a bridging therapy for radiation casualties: a brief review of tocopherol succinate-based approaches.
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Academic Article
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Whole body protection to lethally irradiated mice by oral administration of semipurified fraction of Podophyllum hexandrum and post irradiation treatment of Picrorhiza kurroa.
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Academic Article
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MUC1 is a counter-receptor for myelin-associated glycoprotein (Siglec-4a) and their interaction contributes to adhesion in pancreatic cancer perineural invasion.
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Academic Article
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YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer - Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer.
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Academic Article
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Sonic hedgehog promotes desmoplasia in pancreatic cancer.
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Academic Article
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Visceral adipose tissue remodeling in pancreatic ductal adenocarcinoma cachexia: the role of activin A signaling.
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Academic Article
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Bioinspired Calcium Phosphate Nanoparticles Featuring as Efficient Carrier and Prompter for Macrophage Intervention in Experimental Leishmaniasis.
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Academic Article
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De Novo Lipid Synthesis Facilitates Gemcitabine Resistance through Endoplasmic Reticulum Stress in Pancreatic Cancer.
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Academic Article
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Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells.
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Academic Article
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Novel Validated RP-HPLC Method for Bendamustine Hydrochloride Based on Ion-pair Chromatography: Application in Determining Infusion Stability and Pharmacokinetics.
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Academic Article
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Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments.
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Academic Article
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Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux.
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Academic Article
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Fabrication of 3-O-sn-Phosphatidyl-L-serine Anchored PLGA Nanoparticle Bearing Amphotericin B for Macrophage Targeting.
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Academic Article
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Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells.
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Academic Article
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Overexpression of ecdysoneless in pancreatic cancer and its role in oncogenesis by regulating glycolysis.
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Academic Article
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Osteoprotegerin is sensitive to actomyosin tension in human periodontal ligament fibroblasts.
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Academic Article
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Targeting eosinophils in respiratory diseases: Biological axis, emerging therapeutics and treatment modalities.
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Academic Article
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Podophyllum hexandrum (Himalayan mayapple) extract provides radioprotection by modulating the expression of proteins associated with apoptosis.
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Academic Article
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How does fascin promote cancer metastasis?
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Academic Article
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Ultra high dose rate (35?Gy/sec) radiation does not spare the normal tissue in cardiac and splenic models of lymphopenia and gastrointestinal syndrome.
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Academic Article
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Underscoring the immense potential of chitosan in fighting a wide spectrum of viruses: A plausible molecule against SARS-CoV-2?
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Academic Article
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The malin-laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system.
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Academic Article
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MARK2 regulates chemotherapeutic responses through class IIa HDAC-YAP axis in pancreatic cancer.
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Academic Article
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Protection of the hemopoietic system by Podophyllum hexandrum against gamma radiation-induced damage.
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Academic Article
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Acute and Subacute Toxicity Assessment of Andrographolide-2-hydroxypropyl-ß-cyclodextrin Complex via Oral and Inhalation Route of Administration in Sprague-Dawley Rats.
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Academic Article
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CRTC3 links catecholamine signalling to energy balance.
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Academic Article
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Trans-cellular introduction of HIV-1 protein Nef induces pathogenic response in Caenorhabditis elegans.
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Academic Article
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Arginine-a, ß-dehydrophenylalanine Dipeptide Nanoparticles for pH-Responsive Drug Delivery.
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Academic Article
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Microscale Gene Expression Analysis of Tumor-Associated Macrophages.
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Academic Article
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The cholesterol pathway: impact on immunity and cancer.
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Academic Article
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Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3.
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Academic Article
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Molecular and Physiological Evaluation of Pancreatic Cancer-Induced Cachexia.
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Academic Article
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Hypoxia-Driven Oncometabolite L-2HG Maintains Stemness-Differentiation Balance and Facilitates Immune Evasion in Pancreatic Cancer.
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Academic Article
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CBLB613: a TLR 2/6 agonist, natural lipopeptide of Mycoplasma arginini , as a novel radiation countermeasure.
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Academic Article
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Salivary miR-16, miR-191 and miR-223: intuitive indicators of dominant ovarian follicles in buffaloes.
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Academic Article
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Medicinal Potential of Heterocyclic Compounds from Diverse Natural Sources for the Management of Cancer.
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Academic Article
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An updated review on exosomes: biosynthesis to clinical applications.
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Academic Article
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Ecdysoneless Overexpression Drives Mammary Tumorigenesis through Upregulation of C-MYC and Glucose Metabolism.
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Academic Article
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Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure.
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Academic Article
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Cell surface-associated mucins in signal transduction.
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Academic Article
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Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease.
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Academic Article
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Doxorubicin Hydrochloride Loaded Zymosan-Polyethylenimine Biopolymeric Nanoparticles for Dual 'Chemoimmunotherapeutic' Intervention in Breast Cancer.
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Academic Article
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The laforin-malin complex negatively regulates glycogen synthesis by modulating cellular glucose uptake via glucose transporters.
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Academic Article
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RNA-Binding Protein HuR Regulates Both Mutant and Wild-Type IDH1 in IDH1-Mutated Cancer.
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Academic Article
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From Oncogenic Signaling Pathways to Single-Cell Sequencing of Immune Cells: Changing the Landscape of Cancer Immunotherapy.
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Academic Article
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Success stories of natural product-based hybrid molecules for multi-factorial diseases.
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Academic Article
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Exploiting Arginine Auxotrophy with Pegylated Arginine Deiminase (ADI-PEG20) to Sensitize Pancreatic Cancer to Radiotherapy via Metabolic Dysregulation.
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Academic Article
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p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas.
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Academic Article
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Chemical classes targeting energy supplying GyrB domain of Mycobacterium tuberculosis.
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Academic Article
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O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity.
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Academic Article
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Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.
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Academic Article
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Decreased O-linked GlcNAcylation protects from cytotoxicity mediated by huntingtin exon1 protein fragment.
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Academic Article
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EGFR-Targeted Polymeric Mixed Micelles Carrying Gemcitabine for Treating Pancreatic Cancer.
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Academic Article
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Coarse-Grained Model of SNARE-Mediated Docking.
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Academic Article
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Synergistic anti-glioma effect of a coloaded nano-drug delivery system.
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Academic Article
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Histone methyl transferases: A class of epigenetic opportunities to counter uncontrolled cell proliferation.
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Academic Article
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O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.
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Academic Article
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SIRT1-NOX4 signaling axis regulates cancer cachexia.
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Academic Article
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Preclinical Risk Evaluation of Normal Tissue Injury With Novel Radiosensitizers.
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Academic Article
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The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria.
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Academic Article
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ENT1 blockade by CNX-774 overcomes resistance to DHODH inhibition in pancreatic cancer.
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Academic Article
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Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization.
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Academic Article
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Uncloaking cell-impermeant gold nanorods via tumor microenvironmental cathepsin B facilitates cancer cell penetration and potent radiosensitization.
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Academic Article
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Phosphorylation of spleen tyrosine kinase at Y346 negatively regulates ITAM-mediated signaling and function in platelets.
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Academic Article
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Multiscale Analysis of Neurite Orientation and Spatial Organization in Neuronal Images.
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