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Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth.
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Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth.
Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth. Oncotarget. 2015 Dec 01; 6(38):41146-61.
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PubMed
subject areas
Animals
Antioxidants
Cachexia
Cell Line
Cell Line, Tumor
Cell Proliferation
Dose-Response Relationship, Drug
Female
Glycolysis
Humans
Immunoblotting
Interleukin-6
Metabolome
Mice, Nude
Pancreatic Neoplasms
Proto-Oncogene Proteins c-myc
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Silymarin
STAT3 Transcription Factor
Tumor Burden
Tumor Necrosis Factor-alpha
Xenograft Model Antitumor Assays
authors with profiles
Pankaj Kumar Singh
Kamiya Mehla
Surendra Kumar Shukla