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Anne Kasus-Jacobi

TitleProf,Asoc
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentPharmaceutical Sciences
AddressCPB 255
1110 N Stonewall Ave
Oklahoma City OK 73117
Phone405/271-6593 ext 47019
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    Collapse Research 
    Collapse research activities and funding
    R21EY026229     (KASUS-JACOBI, ANNE)Sep 30, 2016 - Aug 31, 2019
    NIH
    Wound healing mechanisms modulated by novel antimicrobial Peptides
    Role: Principal Investigator
    R21EY018907     (KASUS-JACOBI, ANNE)Sep 30, 2008 - Aug 31, 2011
    NIH
    Detoxification Role of Retinol Dehydrogenases RDH11 and RDH12
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kasus-Jacobi A, Washburn JL, Laurence RB, Pereira HA. Selecting Multitarget Peptides for Alzheimer's Disease. Biomolecules. 2022 09 27; 12(10). PMID: 36291595; PMCID: PMC9599826.
      Citations: 1     Fields:    Translation:HumansAnimals
    2. Kasus-Jacobi A, Washburn JL, Land CA, Pereira HA. Neutrophil Granule Proteins Inhibit Amyloid Beta Aggregation and Neurotoxicity. Curr Alzheimer Res. 2021; 18(5):414-427. PMID: 34429047.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    3. Kasus-Jacobi A, Land CA, Stock AJ, Washburn JL, Pereira HA. Antimicrobial Peptides Derived from the Immune Defense Protein CAP37 Inhibit TLR4 Activation by S100A9. Invest Ophthalmol Vis Sci. 2020 04 09; 61(4):16. PMID: 32298435.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    4. Stock AJ, Kasus-Jacobi A, Pereira HA. The role of neutrophil granule proteins in neuroinflammation and Alzheimer's disease. J Neuroinflammation. 2018 Aug 27; 15(1):240. PMID: 30149799.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    5. Griffith GL, Kasus-Jacobi A, Pereira HA. Bioactive Antimicrobial Peptides as Therapeutics for Corneal Wounds and Infections. Adv Wound Care (New Rochelle). 2017 Jun 01; 6(6):175-190. PMID: 28616359.
      Citations: 8     Fields:    
    6. Kasus-Jacobi A, Griffith GL, Lerner M, Pereira HA. Effect of Cationic Antimicrobial Protein CAP37 on Cytokine Profile during Corneal Wound Healing. J Ocul Dis Ther. 2017; 5:19-27. PMID: 30542656.
      Citations: 3     
    7. Stock AJ, Kasus-Jacobi A, Wren JD, Sjoelund VH, Prestwich GD, Pereira HA. The Role of Neutrophil Proteins on the Amyloid Beta-RAGE Axis. PLoS One. 2016; 11(9):e0163330. PMID: 27676391.
      Citations: 7     Fields:    
    8. Brock AJ, Kasus-Jacobi A, Lerner M, Logan S, Adesina AM, Anne Pereira H. The antimicrobial protein, CAP37, is upregulated in pyramidal neurons during Alzheimer's disease. Histochem Cell Biol. 2015 Oct; 144(4):293-308. PMID: 26170148.
      Citations: 9     Fields:    Translation:HumansCells
    9. Kasus-Jacobi A, Noor-Mohammadi S, Griffith GL, Hinsley H, Mathias L, Pereira HA. A multifunctional peptide based on the neutrophil immune defense molecule, CAP37, has antibacterial and wound-healing properties. J Leukoc Biol. 2015 Feb; 97(2):341-50. PMID: 25412625.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    10. Griffith GL, Kasus-Jacobi A, Lerner MR, Pereira HA. Corneal wound healing, a newly identified function of CAP37, is mediated by protein kinase C delta (PKCd). Invest Ophthalmol Vis Sci. 2014 Jul 15; 55(8):4886-95. PMID: 25028358.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    11. Babizhayev MA, Kasus-Jacobi A, Vishnyakova KS, Yegorov YE. Novel neuroendocrine and metabolic mechanism provides the patented platform for important rejuvenation therapies: targeted therapy of telomere attrition and lifestyle changes of telomerase activity with the timing of neuron-specific imidazole-containing dipeptide-dominant pharmaconutrition provision. Recent Pat Endocr Metab Immune Drug Discov. 2014; 8(3):153-79. PMID: 24910283.
      Citations: 2     Fields:    Translation:HumansCells
    12. Griffith GL, Russell RA, Kasus-Jacobi A, Thavathiru E, Gonzalez ML, Logan S, Pereira HA. CAP37 activation of PKC promotes human corneal epithelial cell chemotaxis. Invest Ophthalmol Vis Sci. 2013 Oct 15; 54(10):6712-23. PMID: 24008408.
      Citations: 12     Fields:    Translation:HumansCells
    13. Marchette LD, Wang H, Li F, Babizhayev MA, Kasus-Jacobi A. Carcinine has 4-hydroxynonenal scavenging property and neuroprotective effect in mouse retina. Invest Ophthalmol Vis Sci. 2012 Jun 20; 53(7):3572-83. PMID: 22577078.
      Citations: 13     Fields:    Translation:AnimalsCells
    14. Babizhayev MA, Khoroshilova-Maslova IP, Kasus-Jacobi A. Novel intraocular and systemic absorption drug delivery and efficacy of N-acetylcarnosine lubricant eye drops or carcinine biologics in pharmaceutical usage and therapeutic vision care. Fundam Clin Pharmacol. 2012 Oct; 26(5):644-78. PMID: 21793899.
      Citations:    Fields:    Translation:HumansAnimals
    15. Mandal MN, Moiseyev GP, Elliott MH, Kasus-Jacobi A, Li X, Chen H, Zheng L, Nikolaeva O, Floyd RA, Ma JX, Anderson RE. Alpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activity. J Biol Chem. 2011 Sep 16; 286(37):32491-501. PMID: 21785167.
      Citations: 41     Fields:    Translation:AnimalsCells
    16. Babizhayev MA, Micans P, Guiotto A, Kasus-Jacobi A. N-acetylcarnosine lubricant eyedrops possess all-in-one universal antioxidant protective effects of L-carnosine in aqueous and lipid membrane environments, aldehyde scavenging, and transglycation activities inherent to cataracts: a clinical study of the new vision-saving drug N-acetylcarnosine eyedrop therapy in a database population of over 50,500 patients. Am J Ther. 2009 Nov-Dec; 16(6):517-33. PMID: 19487926.
      Citations: 10     Fields:    Translation:HumansCells
    17. Marchette LD, Thompson DA, Kravtsova M, Ngansop TN, Mandal MN, Kasus-Jacobi A. Retinol dehydrogenase 12 detoxifies 4-hydroxynonenal in photoreceptor cells. Free Radic Biol Med. 2010 Jan 01; 48(1):16-25. PMID: 19686838.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    18. Babizhayev MA, Kasus-Jacobi A. State of the art clinical efficacy and safety evaluation of N-acetylcarnosine dipeptide ophthalmic prodrug. Principles for the delivery, self-bioactivation, molecular targets and interaction with a highly evolved histidyl-hydrazide structure in the treatment and therapeutic management of a group of sight-threatening eye diseases. Curr Clin Pharmacol. 2009 Jan; 4(1):4-37. PMID: 19149498.
      Citations: 8     Fields:    Translation:HumansCells
    19. Babizhayev MA, Guiotto A, Kasus-Jacobi A. N-Acetylcarnosine and histidyl-hydrazide are potent agents for multitargeted ophthalmic therapy of senile cataracts and diabetic ocular complications. J Drug Target. 2009 Jan; 17(1):36-63. PMID: 19037813.
      Citations: 8     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    20. Mandal MN, Patlolla JM, Zheng L, Agbaga MP, Tran JT, Wicker L, Kasus-Jacobi A, Elliott MH, Rao CV, Anderson RE. Curcumin protects retinal cells from light-and oxidant stress-induced cell death. Free Radic Biol Med. 2009 Mar 01; 46(5):672-9. PMID: 19121385.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    21. Kanan Y, Wicker LD, Al-Ubaidi MR, Mandal NA, Kasus-Jacobi A. Retinol dehydrogenases RDH11 and RDH12 in the mouse retina: expression levels during development and regulation by oxidative stress. Invest Ophthalmol Vis Sci. 2008 Mar; 49(3):1071-8. PMID: 18326732.
      Citations: 10     Fields:    Translation:AnimalsCellsPHPublic Health
    22. Kanan Y, Kasus-Jacobi A, Moiseyev G, Sawyer K, Ma JX, Al-Ubaidi MR. Retinoid processing in cone and Müller cell lines. Exp Eye Res. 2008 Feb; 86(2):344-54. PMID: 18163989.
      Citations: 17     Fields:    Translation:AnimalsCells
    23. Kasus-Jacobi A, Birch DG, Anderson RE. Photoreceptor retinol dehydrogenases. An attempt to characterize the function of Rdh11. Adv Exp Med Biol. 2006; 572:505-11. PMID: 17249616.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    24. Kasus-Jacobi A, Ou J, Birch DG, Locke KG, Shelton JM, Richardson JA, Murphy AJ, Valenzuela DM, Yancopoulos GD, Edwards AO. Functional characterization of mouse RDH11 as a retinol dehydrogenase involved in dark adaptation in vivo. J Biol Chem. 2005 May 27; 280(21):20413-20. PMID: 15790565.
      Citations: 20     Fields:    Translation:AnimalsCells
    25. Cariou B, Bereziat V, Moncoq K, Kasus-Jacobi A, Perdereau D, Le Marcis V, Burnol AF. Regulation and functional roles of Grb14. Front Biosci. 2004 May 01; 9:1626-36. PMID: 14977573.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    26. Kasus-Jacobi A, Ou J, Bashmakov YK, Shelton JM, Richardson JA, Goldstein JL, Brown MS. Characterization of mouse short-chain aldehyde reductase (SCALD), an enzyme regulated by sterol regulatory element-binding proteins. J Biol Chem. 2003 Aug 22; 278(34):32380-9. PMID: 12807874.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    27. Béréziat V, Kasus-Jacobi A, Perdereau D, Cariou B, Girard J, Burnol AF. Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14. J Biol Chem. 2002 Feb 15; 277(7):4845-52. PMID: 11726652.
      Citations: 48     Fields:    Translation:AnimalsCells
    28. Kasus-Jacobi A, Béréziat V, Perdereau D, Girard J, Burnol AF. Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2. Oncogene. 2000 Apr 13; 19(16):2052-9. PMID: 10803466.
      Citations: 12     Fields:    Translation:AnimalsCells
    29. Kasus-Jacobi A, Perdereau D, Auzan C, Clauser E, Van Obberghen E, Mauvais-Jarvis F, Girard J, Burnol AF. Identification of the rat adapter Grb14 as an inhibitor of insulin actions. J Biol Chem. 1998 Oct 02; 273(40):26026-35. PMID: 9748281.
      Citations: 34     Fields:    Translation:AnimalsCells
    30. Kasus-Jacobi A, Perdereau D, Tartare-Deckert S, Van Obberghen E, Girard J, Burnol AF. Evidence for a direct interaction between insulin receptor substrate-1 and Shc. J Biol Chem. 1997 Jul 04; 272(27):17166-70. PMID: 9202037.
      Citations: 5     Fields:    Translation:HumansCells
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