"Pancreatic Elastase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protease of broad specificity, obtained from dried pancreas. Molecular weight is approximately 25,000. The enzyme breaks down elastin, the specific protein of elastic fibers, and digests other proteins such as fibrin, hemoglobin, and albumin. EC 3.4.21.36.
| Descriptor ID |
D010196
|
| MeSH Number(s) |
D08.811.277.656.300.760.560 D08.811.277.656.959.350.560
|
| Concept/Terms |
Pancreatic Elastase- Pancreatic Elastase
- Elastase, Pancreatic
- Pancreatic Elastase I
- Elastase I, Pancreatic
- Elastase
- Pancreatopeptidase
|
Below are MeSH descriptors whose meaning is more general than "Pancreatic Elastase".
Below are MeSH descriptors whose meaning is more specific than "Pancreatic Elastase".
This graph shows the total number of publications written about "Pancreatic Elastase" by people in this website by year, and whether "Pancreatic Elastase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pancreatic Elastase" by people in Profiles.
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Comparative analysis of arterial compliance in mice genetically null for cathepsins K, L, or S. J Biomech. 2022 10; 143:111266.
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Protective effect of an elastase inhibitor in a neuromyelitis optica-like disease driven by a peptide of myelin oligodendroglial glycoprotein. Mult Scler. 2012 Apr; 18(4):398-408.
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Age-dependent changes in the proteolytic-antiproteolytic balance after alcohol and black tea consumption. Toxicol Mech Methods. 2011 Mar; 21(3):209-15.
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Resisting degradation by human elastase: commonality of design features shared by 'canonical' plant and bacterial macrocyclic protease inhibitor scaffolds. Bioorg Med Chem. 2007 Jul 01; 15(13):4618-28.
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Hypertonic saline attenuation of the neutrophil cytotoxic response is reversed upon restoration of normotonicity and reestablished by repeated hypertonic challenge. Surgery. 2001 May; 129(5):567-75.
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Hypertonic saline attenuation of polymorphonuclear neutrophil cytotoxicity: timing is everything. J Trauma. 2000 Mar; 48(3):388-95.
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Selection of human elastase inhibitors from a conformationally constrained combinatorial peptide library. Eur J Biochem. 1999 Dec; 266(2):403-12.
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Matrix-assisted laser desorption of peptides and proteins on a quadrupole ion trap mass spectrometer. Rapid Commun Mass Spectrom. 1993 Jan; 7(1):20-6.