"Chymotrypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.
| Descriptor ID |
D002918
|
| MeSH Number(s) |
D08.811.277.656.300.760.176 D08.811.277.656.959.350.176
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Chymotrypsin".
Below are MeSH descriptors whose meaning is more specific than "Chymotrypsin".
This graph shows the total number of publications written about "Chymotrypsin" by people in this website by year, and whether "Chymotrypsin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chymotrypsin" by people in Profiles.
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Proteasome inhibition 1 h following ischemia protects GRK2 and prevents malignant ventricular tachyarrhythmias and SCD in a model of myocardial infarction. Am J Physiol Heart Circ Physiol. 2008 Mar; 294(3):H1298-303.
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Identification of chymotrypsin inhibitors from a second-generation template assisted combinatorial peptide library. J Pept Sci. 2000 Sep; 6(9):446-52.
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Matrix-assisted laser desorption ionization/quadrupole ion trap mass spectrometry of peptides. Application to the localization of phosphorylation sites on the P protein from Sendai virus. J Biol Chem. 1997 Jan 17; 272(3):1735-41.
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Selection of chymotrypsin inhibitors from a conformationally-constrained combinatorial peptide library. J Mol Biol. 1996 Jun 21; 259(4):819-27.
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Nucleotide sequence coding for the N-terminal region of the matrix protein influenza virus. Eur J Biochem. 1979 May 15; 96(2):363-72.