TLR4-interacting SPA4 peptide improves host defense and alleviates tissue injury in a mouse model of Pseudomonas aeruginosa lung infection.

Awasthi S, Singh B, Ramani V, Xie J, Kosanke S. TLR4-interacting SPA4 peptide improves host defense and alleviates tissue injury in a mouse model of Pseudomonas aeruginosa lung infection. PLoS One. 2019; 14(1):e0210979.

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subject areas

Animals
Animals
Bacterial Load
Bacterial Load
Cells, Cultured
Cells, Cultured
Disease Models, Animal
Disease Models, Animal
Female
Female
Inflammation Mediators
Inflammation Mediators
Mice
Mice
Mice, Inbred C57BL
Mice, Inbred C57BL
Peptide Fragments
Peptide Fragments
Phagocytosis
Phagocytosis
Phagosomes
Phagosomes
Pneumonia, Bacterial
Pneumonia, Bacterial
Protein Binding
Protein Binding
Pseudomonas aeruginosa
Pseudomonas aeruginosa
Pseudomonas Infections
Pseudomonas Infections
Pulmonary Surfactant-Associated Protein A
Pulmonary Surfactant-Associated Protein A
Signal Transduction
Signal Transduction
Toll-Like Receptor 4
Toll-Like Receptor 4

authors with profiles

Shanjana Awasthi
Stanley D Kosanke