"N-Acetylneuraminic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
| Descriptor ID |
D019158
|
| MeSH Number(s) |
D02.241.081.844.562.668.050 D02.241.511.902.562.668.050 D09.067.687.668.030 D09.811.589.668.030
|
| Concept/Terms |
N-Acetylneuraminic Acid- N-Acetylneuraminic Acid
- Acid, N-Acetylneuraminic
- N Acetylneuraminic Acid
- Sialic Acid
- Acid, Sialic
|
Below are MeSH descriptors whose meaning is more general than "N-Acetylneuraminic Acid".
Below are MeSH descriptors whose meaning is more specific than "N-Acetylneuraminic Acid".
This graph shows the total number of publications written about "N-Acetylneuraminic Acid" by people in this website by year, and whether "N-Acetylneuraminic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 0 | 1 | 1 |
| 1995 | 2 | 1 | 3 |
| 1997 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "N-Acetylneuraminic Acid" by people in Profiles.
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Walther T, Karamanska R, Chan RW, Chan MC, Jia N, Air G, Hopton C, Wong MP, Dell A, Malik Peiris JS, Haslam SM, Nicholls JM. Glycomic analysis of human respiratory tract tissues and correlation with influenza virus infection. PLoS Pathog. 2013 Mar; 9(3):e1003223.
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Amonsen M, Smith DF, Cummings RD, Air GM. Human parainfluenza viruses hPIV1 and hPIV3 bind oligosaccharides with alpha2-3-linked sialic acids that are distinct from those bound by H5 avian influenza virus hemagglutinin. J Virol. 2007 Aug; 81(15):8341-5.
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Kumari K, Gulati S, Smith DF, Gulati U, Cummings RD, Air GM. Receptor binding specificity of recent human H3N2 influenza viruses. Virol J. 2007 May 09; 4:42.
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Lommer BS, Ali SM, Bajpai SN, Brouillette WJ, Air GM, Luo M. A benzoic acid inhibitor induces a novel conformational change in the active site of Influenza B virus neuraminidase. Acta Crystallogr D Biol Crystallogr. 2004 Jun; 60(Pt 6):1017-23.
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Finley JB, Atigadda VR, Duarte F, Zhao JJ, Brouillette WJ, Air GM, Luo M. Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site. J Mol Biol. 1999 Nov 12; 293(5):1107-19.
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Gallart T, Angel de la Fuente M, Josep Barceló J, Alberola-Ila J, Lozano F. Desialylation of T lymphocytes overcomes the monocyte dependency of pokeweed mitogen-induced T-cell activation. Immunology. 1997 Jan; 90(1):57-65.
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Singh S, Jedrzejas MJ, Air GM, Luo M, Laver WG, Brouillette WJ. Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction. J Med Chem. 1995 Aug 18; 38(17):3217-25.
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Jedrzejas MJ, Singh S, Brouillette WJ, Laver WG, Air GM, Luo M. Structures of aromatic inhibitors of influenza virus neuraminidase. Biochemistry. 1995 Mar 14; 34(10):3144-51.
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White CL, Janakiraman MN, Laver WG, Philippon C, Vasella A, Air GM, Luo M. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies. J Mol Biol. 1995 Feb 03; 245(5):623-34.
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Janakiraman MN, White CL, Laver WG, Air GM, Luo M. Structure of influenza virus neuraminidase B/Lee/40 complexed with sialic acid and a dehydro analog at 1.8-A resolution: implications for the catalytic mechanism. Biochemistry. 1994 Jul 12; 33(27):8172-9.