"Chromosomal Instability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increased tendency to acquire CHROMOSOME ABERRATIONS when various processes involved in chromosome replication, repair, or segregation are dysfunctional.
| Descriptor ID |
D043171
|
| MeSH Number(s) |
C23.550.210.110 C23.550.362.180 G05.365.590.175.165 G05.370.180
|
| Concept/Terms |
Chromosomal Instability- Chromosomal Instability
- Chromosomal Instabilities
- Instabilities, Chromosomal
- Instability, Chromosomal
- Chromosome Instability
- Chromosome Instabilities
- Instabilities, Chromosome
- Instability, Chromosome
Chromosome Stability- Chromosome Stability
- Chromosome Stabilities
- Stabilities, Chromosome
- Stability, Chromosome
- Chromosomal Stability
- Chromosomal Stabilities
- Stabilities, Chromosomal
- Stability, Chromosomal
|
Below are MeSH descriptors whose meaning is more general than "Chromosomal Instability".
Below are MeSH descriptors whose meaning is more specific than "Chromosomal Instability".
This graph shows the total number of publications written about "Chromosomal Instability" by people in this website by year, and whether "Chromosomal Instability" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2008 | 2 | 1 | 3 |
| 2009 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 2 | 1 | 3 |
| 2018 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Chromosomal Instability" by people in Profiles.
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Rao CV, Farooqui M, Asch AS, Yamada HY. Critical role of mitosis in spontaneous late-onset Alzheimer's disease; from a Shugoshin 1 cohesinopathy mouse model. Cell Cycle. 2018; 17(19-20):2321-2334.
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Wang X, Yang Y, Huycke MM. Microbiome-driven carcinogenesis in colorectal cancer: Models and mechanisms. Free Radic Biol Med. 2017 04; 105:3-15.
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Rao CV, Asch AS, Yamada HY. Emerging links among Chromosome Instability (CIN), cancer, and aging. Mol Carcinog. 2017 03; 56(3):791-803.
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Rao CV, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, Janakiram NB, Mohammed A, Dai W, Yamada HY. Systemic Chromosome Instability Resulted in Colonic Transcriptomic Changes in Metabolic, Proliferation, and Stem Cell Regulators in Sgo1-/+ Mice. Cancer Res. 2016 Feb 01; 76(3):630-42.
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Rao CV, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, Dai W, Yamada HY. Antagonizing pathways leading to differential dynamics in colon carcinogenesis in Shugoshin1 (Sgo1)-haploinsufficient chromosome instability model. Mol Carcinog. 2016 May; 55(5):600-10.
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Yamada HY, Zhang Y, Reddy A, Mohammed A, Lightfoot S, Dai W, Rao CV. Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient mice. Carcinogenesis. 2015 Apr; 36(4):429-40.
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Gorbsky GJ. Cohesion fatigue. Curr Biol. 2013 Nov 18; 23(22):R986-R988.
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Zhao W, Niu G, Shen B, Zheng Y, Gong F, Wang X, Lee J, Mulvihill JJ, Chen X, Li S. High-resolution analysis of copy number variants in adults with simple-to-moderate congenital heart disease. Am J Med Genet A. 2013 Dec; 161A(12):3087-94.
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Yamada HY, Yao Y, Wang X, Zhang Y, Huang Y, Dai W, Rao CV. Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis. Cell Cycle. 2012 Feb 01; 11(3):479-88.
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Kahyo T, Iwaizumi M, Shinmura K, Matsuura S, Nakamura T, Watanabe Y, Yamada H, Sugimura H. A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion. Oncogene. 2011 Nov 03; 30(44):4453-63.