"Complement Factor D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE.
Descriptor ID |
D011416
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MeSH Number(s) |
D08.811.277.300.450 D08.811.277.656.300.760.200 D08.811.277.656.959.350.200 D12.776.124.486.274.045.450
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Concept/Terms |
Complement Factor D- Complement Factor D
- Factor D, Complement
- C3PAse
- Complement Protein D
- Protein D, Complement
- GBGase
- Proactivator Convertase
- Convertase, Proactivator
- Properdin Factor D
- Factor D, Properdin
- C3 Proactivator Convertase
- Convertase, C3 Proactivator
- Adipsin
- C3 Convertase Activator
- Activator, C3 Convertase
- Convertase Activator, C3
- D Component of Complement
- Complement D Component
- 28 kDa Protein, Adipocyte
- C3PA Convertase
- Convertase, C3PA
- Factor D
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Below are MeSH descriptors whose meaning is more general than "Complement Factor D".
Below are MeSH descriptors whose meaning is more specific than "Complement Factor D".
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Below are the most recent publications written about "Complement Factor D" by people in Profiles.
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Eosinophil granule cationic proteins regulate complement. I. Activity on the alternative pathway. J Immunol. 1992 Jul 15; 149(2):643-8.