"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
| Descriptor ID |
D044127
|
| MeSH Number(s) |
G05.308.203
|
| Concept/Terms |
Epigenetic Processes- Epigenetic Processes
- Processes, Epigenetic
- Epigenetics Processes
- Processes, Epigenetics
- Epigenetic Process
- Process, Epigenetic
|
Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".
This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 2 | 3 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 3 | 3 |
| 2013 | 4 | 4 | 8 |
| 2014 | 2 | 2 | 4 |
| 2015 | 7 | 1 | 8 |
| 2016 | 5 | 6 | 11 |
| 2017 | 4 | 4 | 8 |
| 2018 | 8 | 6 | 14 |
| 2019 | 4 | 2 | 6 |
| 2020 | 6 | 3 | 9 |
| 2021 | 4 | 5 | 9 |
| 2022 | 0 | 4 | 4 |
| 2023 | 2 | 2 | 4 |
| 2024 | 1 | 3 | 4 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.
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A satellite cell-dependent epigenetic fingerprint in skeletal muscle identity genes after lifelong physical activity. FASEB J. 2025 Mar 15; 39(5):e70435.
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Impaired Molecular Mechanisms Contributing to Chronic Pain in Patients with Hidradenitis Suppurativa: Exploring Potential Biomarkers and Therapeutic Targets. Int J Mol Sci. 2025 Jan 25; 26(3).
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The potential utility of cord blood DNA methylation in pediatric clinical practice. Epigenomics. 2024 Nov-Nov; 16(21-22):1365-1372.
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Histone acetyltransferases as promising therapeutic targets in glioblastoma resistance. Cancer Lett. 2024 Nov 01; 604:217269.
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Differentially methylated regions interrogated for metastable epialleles associate with offspring adiposity. Epigenomics. 2024; 16(18):1215-1230.
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Developmental Programming of the Fetal Immune System by Maternal Western-Style Diet: Mechanisms and Implications for Disease Pathways in the Offspring. Int J Mol Sci. 2024 May 29; 25(11).
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Epigenetic Landscape and Therapeutic Implication of Gene Isoforms of Doublecortin-Like Kinase 1 for Cancer Stem Cells. Int J Mol Sci. 2023 Nov 16; 24(22).
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RB loss sensitizes cells to replication-associated DNA damage after PARP inhibition by trapping. Life Sci Alliance. 2023 12; 6(12).
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Chronic exposure to environmentally relevant concentration of fluoride impairs osteoblast's collagen synthesis and matrix mineralization: Involvement of epigenetic regulation in skeletal fluorosis. Environ Res. 2023 11 01; 236(Pt 2):116845.
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Epigenetic mechanisms underlying stress-induced visceral pain: Resilience versus vulnerability in a two-hit model of early life stress and chronic adult stress. Neurogastroenterol Motil. 2023 May; 35(5):e14558.