Receptor, Fibroblast Growth Factor, Type 1
"Receptor, Fibroblast Growth Factor, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE PROTEOGLYCAN; and NEURONAL CELL ADHESION MOLECULES. Several variants of the receptor exist due to multiple ALTERNATIVE SPLICING of its mRNA. Fibroblast growth factor receptor 1 contains three extracellular IMMUNOGLOBULIN C2-SET DOMAINS and is a tyrosine kinase that transmits signals through the MAP KINASE SIGNALING SYSTEM.
| Descriptor ID |
D051496
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.177 D12.776.543.750.630.440 D12.776.543.750.750.400.370.500
|
| Concept/Terms |
Receptor, Fibroblast Growth Factor, Type 1- Receptor, Fibroblast Growth Factor, Type 1
- FGFR1 Protein
- Fibroblast Growth Factor Receptor 1
- fms-Like Tyrosine Kinase-2
- fms Like Tyrosine Kinase 2
- CD331 Antigen
- Antigen, CD331
- FGFR1 Tyrosine Kinase
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Fibroblast Growth Factor, Type 1".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Transferases [D08.811.913]
- Phosphotransferases [D08.811.913.696]
- Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
- Protein Kinases [D08.811.913.696.620.682]
- Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
- Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
- Receptor, Fibroblast Growth Factor, Type 1 [D08.811.913.696.620.682.725.400.177]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
- Receptor, Fibroblast Growth Factor, Type 1 [D12.776.543.750.630.440]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Fibroblast Growth Factor [D12.776.543.750.750.400.370]
- Receptor, Fibroblast Growth Factor, Type 1 [D12.776.543.750.750.400.370.500]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Fibroblast Growth Factor, Type 1".
This graph shows the total number of publications written about "Receptor, Fibroblast Growth Factor, Type 1" by people in this website by year, and whether "Receptor, Fibroblast Growth Factor, Type 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 2 | 1 | 3 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Receptor, Fibroblast Growth Factor, Type 1" by people in Profiles.
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Modular self-assembly system for development of oligomeric, highly internalizing and potent cytotoxic conjugates targeting fibroblast growth factor receptors. J Biomed Sci. 2021 Oct 11; 28(1):69.
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FGF1 Fusions with the Fc Fragment of IgG1 for the Assembly of GFPpolygons-Mediated Multivalent Complexes Recognizing FGFRs. Biomolecules. 2021 07 23; 11(8).
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Encephalocraniocutaneous Lipomatosis. J Pediatr Hematol Oncol. 2018 10; 40(7):553-554.
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FGFR1 underlies obesity-associated progression of estrogen receptor-positive breast cancer after estrogen deprivation. JCI Insight. 2018 07 26; 3(14).
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Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors. Mol Cell Proteomics. 2018 05; 17(5):850-870.
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Heparan Sulfate Domains Required for Fibroblast Growth Factor 1 and 2 Signaling through Fibroblast Growth Factor Receptor 1c. J Biol Chem. 2017 02 10; 292(6):2495-2509.
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Endothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells. J Cell Sci. 2015 Aug 15; 128(16):2983-8.