Receptors, Platelet-Derived Growth Factor
"Receptors, Platelet-Derived Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.
| Descriptor ID |
D017479
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.900 D12.776.543.750.630.625 D12.776.543.750.750.400.630
|
| Concept/Terms |
Receptors, Platelet-Derived Growth Factor- Receptors, Platelet-Derived Growth Factor
- Receptors, Platelet Derived Growth Factor
- Platelet-Derived Growth Factor Receptors
- Platelet Derived Growth Factor Receptors
- Receptors, PDGF
- PDGF Receptor
- Receptor, PDGF
- PDGF Receptors
- Platelet-Derived Growth Factor Receptor
- Platelet Derived Growth Factor Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Platelet-Derived Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Platelet-Derived Growth Factor".
This graph shows the total number of publications written about "Receptors, Platelet-Derived Growth Factor" by people in this website by year, and whether "Receptors, Platelet-Derived Growth Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Platelet-Derived Growth Factor" by people in Profiles.
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Involvement of PDGF in fibrosis and scleroderma: recent insights from animal models and potential therapeutic opportunities. Curr Rheumatol Rep. 2013 Feb; 15(2):304.
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ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression. Oncogene. 2009 Feb 05; 28(5):638-50.
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GM1 inhibits early signaling events mediated by PDGF receptor in cultured human glioma cells. Anticancer Res. 1999 Nov-Dec; 19(6B):5007-13.
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B-cell antigen receptor-induced apoptosis requires both Ig alpha and Ig beta. Blood. 1997 Mar 01; 89(5):1513-20.