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Ammaji Rajala

TitleAsst,Research II
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentOphthalmology
AddressDMEI 409
608 Stanton L Young Blvd
Oklahoma City OK 73104
Phone405/271-8001
Fax0
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rajala RVS, McCauley A, Rajala R, Teel K, Rajala A. Regulation of Phosphoinositide Levels in the Retina by Protein Tyrosine Phosphatase 1B and Growth Factor Receptor-Bound Protein 14. Biomolecules. 2021 Apr 19; 11(4). PMID: 33921658.
      Citations:    Fields:    
    2. Rajala A, He F, Anderson RE, Wensel TG, Rajala RVS. Loss of Class III Phosphoinositide 3-Kinase Vps34 Results in Cone Degeneration. Biology (Basel). 2020 Nov 07; 9(11). PMID: 33171845.
      Citations:    
    3. Rajala A, McCauley A, Brush RS, Nguyen K, Rajala RVS. Phosphoinositide Lipids in Ocular Tissues. Biology (Basel). 2020 Jun 12; 9(6). PMID: 32545642.
      Citations:    
    4. Rajala A, Soni K, Rajala RVS. Metabolic and Non-metabolic Roles of Pyruvate Kinase M2 Isoform in Diabetic Retinopathy. Sci Rep. 2020 05 04; 10(1):7456. PMID: 32366925.
      Citations: 1     Fields:    Translation:AnimalsCells
    5. Rajala A, Rajala RVS. A non-canonical rhodopsin-mediated insulin receptor signaling pathway in retinal photoreceptor neurons. Cell Biol Int. 2020 Apr; 44(4):1020-1027. PMID: 31889373.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Rajala A, Wang Y, Soni K, Rajala RVS. Pyruvate kinase M2 isoform deletion in cone photoreceptors results in age-related cone degeneration. Cell Death Dis. 2018 07 03; 9(7):737. PMID: 29970877.
      Citations: 10     Fields:    Translation:AnimalsCells
    7. Rajala A, Wang Y, Brush RS, Tsantilas K, Jankowski CSR, Lindsay KJ, Linton JD, Hurley JB, Anderson RE, Rajala RVS. Pyruvate kinase M2 regulates photoreceptor structure, function, and viability. Cell Death Dis. 2018 02 14; 9(2):240. PMID: 29445082.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    8. Wang Y, Rajala A, Rajala RVS. Nanoparticles as Delivery Vehicles for the Treatment of Retinal Degenerative Diseases. Adv Exp Med Biol. 2018; 1074:117-123. PMID: 29721935.
      Citations: 1     Fields:    Translation:HumansAnimals
    9. Rajala A, Wang Y, Rajala RVS. Constitutive Activation Mutant mTOR Promote Cone Survival in Retinitis Pigmentosa Mice. Adv Exp Med Biol. 2018; 1074:491-497. PMID: 29721981.
      Citations:    Fields:    Translation:AnimalsCells
    10. Rajala RVS, Rajala A. Redundant and Nonredundant Functions of Akt Isoforms in the Retina. Adv Exp Med Biol. 2018; 1074:585-591. PMID: 29721991.
      Citations:    Fields:    Translation:HumansAnimalsCells
    11. Rajala A, Wang Y, Abcouwer SF, Gardner TW, Rajala RVS. Developmental and light regulation of tumor suppressor protein PP2A in the retina. Oncotarget. 2018 Jan 05; 9(2):1505-1523. PMID: 29416710.
      Citations: 3     Fields:    
    12. Rajala RV, Rajala A, Kooker C, Wang Y, Anderson RE. The Warburg Effect Mediator Pyruvate Kinase M2 Expression and Regulation in the Retina. Sci Rep. 2016 11 24; 6:37727. PMID: 27883057.
      Citations: 21     Fields:    Translation:AnimalsCells
    13. Rajala A, Wang Y, Rajala RV. Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival. Oncotarget. 2016 Jul 26; 7(30):46924-46942. PMID: 27391439.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    14. Wang Y, Rajala A, Cao B, Ranjo-Bishop M, Agbaga MP, Mao C, Rajala RV. Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo. Theranostics. 2016; 6(10):1514-27. PMID: 27446487.
      Citations: 8     Fields:    Translation:AnimalsCells
    15. Wang Y, Rajala A, Rajala RV. Lipid Nanoparticles for Ocular Gene Delivery. J Funct Biomater. 2015 Jun 08; 6(2):379-94. PMID: 26062170.
      Citations:    
    16. Rajala RV, Ranjo-Bishop M, Wang Y, Rajala A, Anderson RE. The p110a isoform of phosphoinositide 3-kinase is essential for cone photoreceptor survival. Biochimie. 2015 May; 112:35-40. PMID: 25742742.
      Citations: 6     Fields:    Translation:AnimalsCells
    17. Gupta VK, Rajala A, Rajala RV. Non-canonical regulation of phosphatidylinositol 3-kinase gamma isoform activity in retinal rod photoreceptor cells. Cell Commun Signal. 2015 Feb 03; 13:7. PMID: 25644171.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    18. Woodruff ML, Rajala A, Fain GL, Rajala RV. Effect of knocking down the insulin receptor on mouse rod responses. Sci Rep. 2015 Jan 19; 5:7858. PMID: 25598343.
      Citations: 1     Fields:    Translation:AnimalsCells
    19. Rajala A, Wang Y, Zhu Y, Ranjo-Bishop M, Ma JX, Mao C, Rajala RV. Nanoparticle-assisted targeted delivery of eye-specific genes to eyes significantly improves the vision of blind mice in vivo. . 2014 Sep 10; 14(9):5257-63. PMID: 25115433.
      Citations:    
    20. Rajala RV, Rajala A, Morris AJ, Anderson RE. Phosphoinositides: minor lipids make a major impact on photoreceptor cell functions. Sci Rep. 2014 Jun 26; 4:5463. PMID: 24964953.
      Citations: 6     Fields:    Translation:AnimalsCells
    21. Rajala RV, Basavarajappa DK, Dighe R, Rajala A. Spatial and temporal aspects and the interplay of Grb14 and protein tyrosine phosphatase-1B on the insulin receptor phosphorylation. Cell Commun Signal. 2013 Dec 18; 11:96. PMID: 24350791.
      Citations: 5     Fields:    Translation:AnimalsCells
    22. Rajala RV, Rajala A. Neuroprotective role of protein tyrosine phosphatase-1B in rod photoreceptor neurons. Protein Cell. 2013 Dec; 4(12):890-2. PMID: 24203758.
      Citations: 3     Fields:    Translation:AnimalsCells
    23. Woodruff ML, Rajala A, Fain GL, Rajala RV. Modulation of mouse rod photoreceptor responses by Grb14 protein. J Biol Chem. 2014 Jan 03; 289(1):358-64. PMID: 24273167.
      Citations: 6     Fields:    Translation:AnimalsCells
    24. Rajala A, Gupta VK, Anderson RE, Rajala RV. Light activation of the insulin receptor regulates mitochondrial hexokinase. A possible mechanism of retinal neuroprotection. Mitochondrion. 2013 Nov; 13(6):566-76. PMID: 23993956.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    25. Rajala A, Dighe R, Agbaga MP, Anderson RE, Rajala RV. Insulin receptor signaling in cones. J Biol Chem. 2013 Jul 05; 288(27):19503-15. PMID: 23673657.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    26. Rajala A, Dilly AK, Rajala RV. Protein tyrosine phosphatase-1B regulates the tyrosine phosphorylation of the adapter Grb2-associated binder 1 (Gab1) in the retina. Cell Commun Signal. 2013 Mar 22; 11(1):20. PMID: 23521888.
      Citations: 1     Fields:    
    27. Gupta VK, Rajala A, Rajala RV. Insulin receptor regulates photoreceptor CNG channel activity. Am J Physiol Endocrinol Metab. 2012 Dec 01; 303(11):E1363-72. PMID: 23032687.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    28. Rajala RV, Rajala A, Gupta VK. Conservation and divergence of Grb7 family of Ras-binding domains. Protein Cell. 2012 Jan; 3(1):60-70. PMID: 22271596.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    29. Gupta VK, Rajala A, Rajala RV. Ras-associating domain proteins: a new class of cyclic nucleotide-gated channel modulators. Adv Exp Med Biol. 2012; 723:777-82. PMID: 22183406.
      Citations:    Fields:    Translation:HumansCells
    30. Gupta VK, Rajala A, Rodgers KK, Rajala RV. Mechanism involved in the modulation of photoreceptor-specific cyclic nucleotidegated channel by the tyrosine kinase adapter protein Grb14. Protein Cell. 2011 Nov; 2(11):906-17. PMID: 22180090.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    31. Basavarajappa DK, Gupta VK, Dighe R, Rajala A, Rajala RV. Phosphorylated Grb14 is an endogenous inhibitor of retinal protein tyrosine phosphatase 1B, and light-dependent activation of Src phosphorylates Grb14. Mol Cell Biol. 2011 Oct; 31(19):3975-87. PMID: 21791607.
      Citations: 16     Fields:    Translation:AnimalsCells
    32. Gupta VK, Rajala A, Daly RJ, Rajala RV. Growth factor receptor-bound protein 14: a new modulator of photoreceptor-specific cyclic-nucleotide-gated channel. . 2010 Nov; 11(11):861-7. PMID: 20890309.
      Citations:    
    33. Rajala RV, Tanito M, Neel BG, Rajala A. Enhanced retinal insulin receptor-activated neuroprotective survival signal in mice lacking the protein-tyrosine phosphatase-1B gene. J Biol Chem. 2010 Mar 19; 285(12):8894-904. PMID: 20061388.
      Citations: 24     Fields:    Translation:AnimalsCells
    34. Rajala RV, Rajala A, Brush RS, Rotstein NP, Politi LE. Insulin receptor signaling regulates actin cytoskeletal organization in developing photoreceptors. J Neurochem. 2009 Sep; 110(5):1648-60. PMID: 19575708.
      Citations: 4     Fields:    Translation:AnimalsCells
    35. Rajala A, Daly RJ, Tanito M, Allen DT, Holt LJ, Lobanova ES, Arshavsky VY, Rajala RV. Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation. Biochemistry. 2009 Jun 23; 48(24):5563-72. PMID: 19438210.
      Citations: 20     Fields:    Translation:AnimalsCells
    36. Rajala RV, Rajala A. Cytoskeletal components enhance the autophosphorylation of retinal insulin receptor. Chem Biol Interact. 2009 Jul 15; 180(2):245-53. PMID: 19497423.
      Citations:    Fields:    Translation:AnimalsCells
    37. Rajala RV, Wiskur B, Tanito M, Callegan M, Rajala A. Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity. Invest Ophthalmol Vis Sci. 2009 Mar; 50(3):1033-40. PMID: 19029027.
      Citations: 30     Fields:    Translation:AnimalsCells
    38. Li G, Rajala A, Wiechmann AF, Anderson RE, Rajala RV. Activation and membrane binding of retinal protein kinase Balpha/Akt1 is regulated through light-dependent generation of phosphoinositides. J Neurochem. 2008 Dec; 107(5):1382-97. PMID: 18823366.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    39. Rajala A, Tanito M, Le YZ, Kahn CR, Rajala RV. Loss of neuroprotective survival signal in mice lacking insulin receptor gene in rod photoreceptor cells. J Biol Chem. 2008 Jul 11; 283(28):19781-92. PMID: 18480052.
      Citations: 51     Fields:    Translation:AnimalsCells
    40. Rajala A, Anderson RE, Ma JX, Lem J, Al-Ubaidi MR, Rajala RVS. G-protein-coupled receptor rhodopsin regulates the phosphorylation of retinal insulin receptor. J Biol Chem. 2007 Mar 30; 282(13):9865-9873. PMID: 17272282.
      Citations: 31     Fields:    Translation:AnimalsCells
    41. Rajala RV, Chan MD, Rajala A. Lipid-protein interactions of growth factor receptor-bound protein 14 in insulin receptor signaling. Biochemistry. 2005 Nov 29; 44(47):15461-71. PMID: 16300394.
      Citations: 9     Fields:    Translation:AnimalsCells
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