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Zoltan Ungvari

TitleProf
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentNeurosurgery
AddressBRC 1315
975 NE 10th St
Oklahoma City OK 73104
Phone405/271-7622 ext 47809
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    Collapse Research 
    Collapse research activities and funding
    RF1AG072295     (UNGVARI, ZOLTAN ISTVAN)Jun 1, 2021 - May 31, 2024
    NIH
    Cerebromicrovascular rejuvenation by heterochronic blood exchange
    Role: Principal Investigator
    R01AG068295     (CSISZAR, ANNA)Aug 1, 2020 - Jul 31, 2025
    NIH
    Age-related vascular cognitive impairment: role of endothelial senescence
    Role: Co-Principal Investigator
    R01NS100782     (UNGVARI, ZOLTAN ISTVAN)Dec 1, 2017 - Nov 30, 2022
    NIH
    Radiation-induced astrocyte dysfunction and cognitive decline
    Role: Principal Investigator
    R01AG055395     (UNGVARI, ZOLTAN ISTVAN)Sep 15, 2017 - May 31, 2022
    NIH
    Cerebral microhemorrhages and gait dysfunction in aging
    Role: Principal Investigator
    R01AT006526     (UNGVARI, ZOLTAN ISTVAN)Sep 1, 2010 - Aug 31, 2016
    NIH
    Role of SIRT1 in vasoprotection
    Role: Principal Investigator
    R01HL077256     (UNGVARI, ZOLTAN ISTVAN)Mar 15, 2006 - Feb 28, 2011
    NIH
    Hemodynamic forces regulate BMPs in coronary arteries
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ungvari Z, Tab?k AG, Adany R, Purebl G, Kaposv?ri C, Fazekas-Pongor V, Cs?po T, Szarvas Z, Horv?th K, Mukli P, Balog P, Bodizs R, Ujma P, Stauder A, Belsky DW, Kov?cs I, Yabluchanskiy A, Maier AB, Moizs M, ?stlin P, Yon Y, Varga P, Vok? Z, Papp M, Tak?cs I, V?s?rhelyi B, Torzsa P, Ferdinandy P, Csiszar A, Beny? Z, Szab? AJ, D?rnyei G, Kivim?ki M, Kellermayer M, Merkely B. The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging. Geroscience. 2023 Dec 07. PMID: 38060158.
      Citations: 2     Fields:    Translation:Humans
    2. Ungvari Z, Fazekas-Pongor V, Csiszar A, Kunutsor SK. The multifaceted benefits of walking for healthy aging: from Blue Zones to molecular mechanisms. Geroscience. 2023 Jul 26. PMID: 37495893.
      Citations: 2     Fields:    Translation:Humans
    3. Toth L, Czigler A, Hegedus E, Komaromy H, Amrein K, Czeiter E, Yabluchanskiy A, Koller A, Orsi G, Perlaki G, Schwarcz A, Buki A, Ungvari Z, Toth PJ. Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults. Geroscience. 2022 Jul 23. PMID: 35869380.
      Citations: 13     Fields:    Translation:Animals
    4. Mukli P, Wu DH, Csipo T, Owens CD, Lipecz A, Racz FS, Zouein FA, Tabak A, Csiszar A, Ungvari Z, Tsitouras PD, Yabluchanskiy A. Urinary Biomarkers of Oxidative Stress in Aging: Implications for Prediction of Accelerated Biological Age in Prospective Cohort Studies. Oxid Med Cell Longev. 2022; 2022:6110226. PMID: 35571254.
      Citations: 3     Fields:    Translation:Humans
    5. Prodan CI, Batra A, Ungvari Z, Liotta EM. Stringent public health measures during COVID-19 across ischemic stroke care systems: the potential impact of patient perceptions on health care-seeking behaviors. Geroscience. 2022 06; 44(3):1255-1262. PMID: 35467316.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    6. Owens CD, Mukli P, Csipo T, Lipecz A, Silva-Palacios F, Dasari TW, Tarantini S, Gardner AW, Montgomery PS, Waldstein SR, Kellawan JM, Nyul-Toth A, Balasubramanian P, Sotonyi P, Csiszar A, Ungvari Z, Yabluchanskiy A. Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults. Am J Physiol Heart Circ Physiol. 2022 06 01; 322(6):H924-H935. PMID: 35333116.
      Citations: 9     Fields:    Translation:Humans
    7. Miller LR, Tarantini S, Nyúl-Tóth Á, Johnston MP, Martin T, Bullen EC, Bickel MA, Sonntag WE, Yabluchanskiy A, Csiszar A, Ungvari ZI, Elliott MH, Conley SM. Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging. Front Aging Neurosci. 2022; 14:788296. PMID: 35356301.
      Citations: 8     
    8. Kiss T, Nyúl-Tóth Á, Gulej R, Tarantini S, Csipo T, Mukli P, Ungvari A, Balasubramanian P, Yabluchanskiy A, Benyo Z, Conley SM, Wren JD, Garman L, Huffman DM, Csiszar A, Ungvari Z. Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling. Geroscience. 2022 04; 44(2):953-981. PMID: 35124764.
      Citations: 9     Fields:    Translation:AnimalsCells
    9. Kiss T, Nyúl-Tóth Á, DelFavero J, Balasubramanian P, Tarantini S, Faakye J, Gulej R, Ahire C, Ungvari A, Yabluchanskiy A, Wiley G, Garman L, Ungvari Z, Csiszar A. Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain. Geroscience. 2022 04; 44(2):661-681. PMID: 35098444.
      Citations: 17     Fields:    Translation:AnimalsCells
    10. Nyul-Toth A, Fulop GA, Tarantini S, Kiss T, Ahire C, Faakye JA, Ungvari A, Toth P, Toth A, Csiszar A, Ungvari Z. Cerebral venous congestion exacerbates cerebral microhemorrhages in mice. Geroscience. 2022 04; 44(2):805-816. PMID: 34989944.
      Citations: 10     Fields:    Translation:Animals
    11. Csipo T, Lipecz A, Owens C, Mukli P, Perry JW, Tarantini S, Balasubramanian P, Nyúl-Tóth Á, Yabluchanska V, Sorond FA, Kellawan JM, Purebl G, Sonntag WE, Csiszar A, Ungvari Z, Yabluchanskiy A. Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses. Sci Rep. 2021 10 25; 11(1):20994. PMID: 34697326.
      Citations: 8     Fields:    Translation:HumansCells
    12. Whitehead SN, Bruno A, Burns JM, Carmichael ST, Csiszar A, Edwards JD, Elahi FM, Faraco G, Gould DB, Gustafson DR, Hachinski V, Rosenberg G, Sorond FA, Shih AY, Tse KH, Ungvari Z, Wilcock DM, Zuloaga KL, Barone FC. Expanding the horizon of research into the pathogenesis of the white matter diseases: Proceedings of the 2021 Annual Workshop of the Albert Research Institute for White Matter and Cognition. Geroscience. 2022 02; 44(1):25-37. PMID: 34606040.
      Citations: 1     Fields:    Translation:Humans
    13. Toth L, Czigler A, Horvath P, Szarka N, Kornyei B, Toth A, Schwarcz A, Ungvari Z, Buki A, Toth P. The Effect of Mild Traumatic Brain Injury on Cerebral Microbleeds in Aging. Front Aging Neurosci. 2021; 13:717391. PMID: 34658836.
      Citations:    
    14. Gardner AW, Montgomery PS, Wang M, Shen B, Casanegra AI, Silva-Palacios F, Ungvari Z, Yabluchanskiy A, Csiszar A, Waldstein SR. Cognitive decrement in older adults with symptomatic peripheral artery disease. Geroscience. 2021 10; 43(5):2455-2465. PMID: 34498199.
      Citations: 10     Fields:    Translation:Humans
    15. Valencak TG, Csiszar A, Szalai G, Podlutsky A, Tarantini S, Fazekas-Pongor V, Papp M, Ungvari Z. Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission. Geroscience. 2021 10; 43(5):2305-2320. PMID: 34460063.
      Citations: 9     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    16. Tarantini S, Balasubramanian P, Delfavero J, Csipo T, Yabluchanskiy A, Kiss T, Nyúl-Tóth Á, Mukli P, Toth P, Ahire C, Ungvari A, Benyo Z, Csiszar A, Ungvari Z. Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice. Geroscience. 2021 10; 43(5):2427-2440. PMID: 34427858.
      Citations: 28     Fields:    Translation:Animals
    17. Tarantini S, Yabluchanskiy A, Lindsey ML, Csiszar A, Ungvari Z. Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice. Geroscience. 2021 10; 43(5):2611-2619. PMID: 34415518.
      Citations: 8     Fields:    Translation:Animals
    18. Tarantini S, Nyúl-Tóth Á, Yabluchanskiy A, Csipo T, Mukli P, Balasubramanian P, Ungvari A, Toth P, Benyo Z, Sonntag WE, Ungvari Z, Csiszar A. Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype. Geroscience. 2021 10; 43(5):2387-2394. PMID: 34383203.
      Citations: 23     Fields:    Translation:AnimalsCells
    19. Ungvari Z, Adany R. The future of healthy aging: translation of geroscience discoveries to public health practice. Eur J Public Health. 2021 07 13; 31(3):455-456. PMID: 33594423.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    20. Nyul-Toth A, DelFavero J, Mukli P, Tarantini A, Ungvari A, Yabluchanskiy A, Csiszar A, Ungvari Z, Tarantini S. Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease. Geroscience. 2021 08; 43(4):1947-1957. PMID: 34160781.
      Citations: 7     Fields:    Translation:HumansAnimals
    21. Mukli P, Csipo T, Lipecz A, Stylianou O, Racz FS, Owens CD, Perry JW, Tarantini S, Sorond FA, Kellawan JM, Purebl G, Yang Y, Sonntag WE, Csiszar A, Ungvari ZI, Yabluchanskiy A. Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: A near-infrared spectroscopy study. Brain Behav. 2021 08; 11(8):e02135. PMID: 34156165.
      Citations: 7     Fields:    Translation:Humans
    22. Ungvari Z, Toth P, Tarantini S, Prodan CI, Sorond F, Merkely B, Csiszar A. Hypertension-induced cognitive impairment: from pathophysiology to public health. Nat Rev Nephrol. 2021 Oct; 17(10):639-654. PMID: 34127835.
      Citations: 89     Fields:    Translation:HumansPHPublic Health
    23. Csipo T, Lipecz A, Mukli P, Bahadli D, Abdulhussein O, Owens CD, Tarantini S, Hand RA, Yabluchanska V, Kellawan JM, Sorond F, James JA, Csiszar A, Ungvari ZI, Yabluchanskiy A. Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults. PLoS One. 2021; 16(5):e0250043. PMID: 34010279.
      Citations: 22     Fields:    Translation:Humans
    24. Csipo T, Cassidy BR, Balasubramanian P, Drevets DA, Ungvari ZI, Yabluchanskiy A. Endothelial Dysfunction and Impaired Neurovascular Coupling Responses Precede Cognitive Impairment in a Mouse Model of Geriatric Sepsis. Front Aging Neurosci. 2021; 13:644733. PMID: 34054502.
      Citations: 4     
    25. Szarka N, Szellar D, Kiss S, Farkas N, Szakacs Z, Czigler A, Ungvari Z, Hegyi P, Buki A, Toth P. Effect of Growth Hormone on Neuropsychological Outcomes and Quality of Life of Patients with Traumatic Brain Injury: A Systematic Review. J Neurotrauma. 2021 06 01; 38(11):1467-1483. PMID: 33677992.
      Citations: 5     Fields:    Translation:Humans
    26. Tarantini S, Balasubramanian P, Yabluchanskiy A, Ashpole NM, Logan S, Kiss T, Ungvari A, Nyúl-Tóth Á, Schwartzman ML, Benyo Z, Sonntag WE, Csiszar A, Ungvari Z. IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging. Geroscience. 2021 04; 43(2):901-911. PMID: 33674953.
      Citations: 19     Fields:    Translation:AnimalsCells
    27. Nyúl-Tóth Á, Tarantini S, DelFavero J, Yan F, Balasubramanian P, Yabluchanskiy A, Ahire C, Kiss T, Csipo T, Lipecz A, Farkas AE, Wilhelm I, Krizbai IA, Tang Q, Csiszar A, Ungvari Z. Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography. Am J Physiol Heart Circ Physiol. 2021 04 01; 320(4):H1370-H1392. PMID: 33543687.
      Citations: 20     Fields:    Translation:Animals
    28. Huffman DM, Csiszar A, Ungvari Z. Heterochronic blood exchange attenuates age-related neuroinflammation and confers cognitive benefits: do microvascular protective effects play a role? Geroscience. 2021 02; 43(1):111-113. PMID: 33511487.
      Citations: 3     Fields:    Translation:Humans
    29. Balasubramanian P, Kiss T, Tarantini S, Nyúl-Tóth Á, Ahire C, Yabluchanskiy A, Csipo T, Lipecz A, Tabak A, Institoris A, Csiszar A, Ungvari Z. Obesity-induced cognitive impairment in older adults: a microvascular perspective. Am J Physiol Heart Circ Physiol. 2021 02 01; 320(2):H740-H761. PMID: 33337961.
      Citations: 30     Fields:    Translation:HumansAnimals
    30. Tarantini S, Csiszar A, Ungvari Z. Midlife Obesity Impairs Neurovascular Coupling Responses. Obesity (Silver Spring). 2021 01; 29(1):17. PMID: 33280232.
      Citations: 3     Fields:    Translation:Animals
    31. Institoris A, Murphy-Royal C, Tarantini S, Yabluchanskiy A, Haidey JN, Csiszar A, Ungvari Z, Gordon GR. Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling. Geroscience. 2021 02; 43(1):197-212. PMID: 33094399.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    32. Czakó C, Kovács T, Ungvari Z, Csiszar A, Yabluchanskiy A, Conley S, Csipo T, Lipecz A, Horváth H, Sándor GL, István L, Logan T, Nagy ZZ, Kovács I. Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis. Geroscience. 2020 12; 42(6):1499-1525. PMID: 33011937.
      Citations: 44     Fields:    Translation:Humans
    33. Toth L, Czigler A, Horvath P, Kornyei B, Szarka N, Schwarcz A, Ungvari Z, Buki A, Toth P. Traumatic brain injury-induced cerebral microbleeds in the elderly. Geroscience. 2021 02; 43(1):125-136. PMID: 33011936.
      Citations: 6     Fields:    Translation:Humans
    34. Nyúl-Tóth Á, Tarantini S, Kiss T, Toth P, Galvan V, Tarantini A, Yabluchanskiy A, Csiszar A, Ungvari Z. Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease. Geroscience. 2020 12; 42(6):1685-1698. PMID: 32844283.
      Citations: 26     Fields:    Translation:HumansAnimals
    35. Csiszar A, Jakab F, Valencak TG, Lanszki Z, Tóth GE, Kemenesi G, Tarantini S, Fazekas-Pongor V, Ungvari Z. Companion animals likely do not spread COVID-19 but may get infected themselves. Geroscience. 2020 10; 42(5):1229-1236. PMID: 32766998.
      Citations: 25     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    36. Kiss T, Nyúl-Tóth Á, Balasubramanian P, Tarantini S, Ahire C, DelFavero J, Yabluchanskiy A, Csipo T, Farkas E, Wiley G, Garman L, Csiszar A, Ungvari Z. Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain. Geroscience. 2020 04; 42(2):429-444. PMID: 32236824.
      Citations: 63     Fields:    Translation:AnimalsCells
    37. Kiss T, Tarantini S, Csipo T, Balasubramanian P, Nyúl-Tóth Á, Yabluchanskiy A, Wren JD, Garman L, Huffman DM, Csiszar A, Ungvari Z. Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood. Geroscience. 2020 04; 42(2):727-748. PMID: 32172434.
      Citations: 31     Fields:    Translation:HumansAnimals
    38. Ungvari Z, Tarantini S, Sorond F, Merkely B, Csiszar A. Mechanisms of Vascular Aging, A Geroscience Perspective: JACC Focus Seminar. J Am Coll Cardiol. 2020 03 03; 75(8):931-941. PMID: 32130929.
      Citations: 71     Fields:    Translation:HumansAnimals
    39. Zhao Y, Kiss T, DelFavero J, Li L, Li X, Zheng L, Wang J, Jiang C, Shi J, Ungvari Z, Csiszar A, Zhang XA. CD82-TRPM7-Numb signaling mediates age-related cognitive impairment. Geroscience. 2020 04; 42(2):595-611. PMID: 32088828.
      Citations: 9     Fields:    Translation:HumansAnimals
    40. Kiss T, Nyúl-Tóth Á, Balasubramanian P, Tarantini S, Ahire C, Yabluchanskiy A, Csipo T, Farkas E, Wren JD, Garman L, Csiszar A, Ungvari Z. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020 04; 42(2):527-546. PMID: 32056076.
      Citations: 60     Fields:    Translation:AnimalsCells
    41. Yabluchanskiy A, Tarantini S, Balasubramanian P, Kiss T, Csipo T, Fülöp GA, Lipecz A, Ahire C, DelFavero J, Nyul-Toth A, Sonntag WE, Schwartzman ML, Campisi J, Csiszar A, Ungvari Z. Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice. Geroscience. 2020 04; 42(2):409-428. PMID: 31960269.
      Citations: 47     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    42. Lipecz A, Miller L, Kovacs I, Czakó C, Csipo T, Baffi J, Csiszar A, Tarantini S, Ungvari Z, Yabluchanskiy A, Conley S. Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions. Geroscience. 2019 12; 41(6):813-845. PMID: 31797238.
      Citations: 33     Fields:    Translation:Humans
    43. Fulop GA, Ahire C, Csipo T, Tarantini S, Kiss T, Balasubramanian P, Yabluchanskiy A, Farkas E, Toth A, Nyúl-Tóth Á, Toth P, Csiszar A, Ungvari Z. Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice. Geroscience. 2019 10; 41(5):575-589. PMID: 31691147.
      Citations: 31     Fields:    Translation:AnimalsCells
    44. Csipo T, Mukli P, Lipecz A, Tarantini S, Bahadli D, Abdulhussein O, Owens C, Kiss T, Balasubramanian P, Nyúl-Tóth Á, Hand RA, Yabluchanska V, Sorond FA, Csiszar A, Ungvari Z, Yabluchanskiy A. Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans. Geroscience. 2019 10; 41(5):495-509. PMID: 31676966.
      Citations: 44     Fields:    Translation:Humans
    45. Tarantini S, Yabluchanskiy A, Csipo T, Fulop G, Kiss T, Balasubramanian P, DelFavero J, Ahire C, Ungvari A, Nyúl-Tóth Á, Farkas E, Benyo Z, Tóth A, Csiszar A, Ungvari Z. Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging. Geroscience. 2019 10; 41(5):533-542. PMID: 31679124.
      Citations: 57     Fields:    Translation:Animals
    46. Czigler A, Toth L, Szarka N, Szilágyi K, Kellermayer Z, Harci A, Vecsernyes M, Ungvari Z, Szolics A, Koller A, Buki A, Toth P. Prostaglandin E2, a postulated mediator of neurovascular coupling, at low concentrations dilates whereas at higher concentrations constricts human cerebral parenchymal arterioles. Prostaglandins Other Lipid Mediat. 2020 02; 146:106389. PMID: 31689497.
      Citations: 10     Fields:    Translation:Humans
    47. Ungvari Z, Tarantini S, Nyúl-Tóth Á, Kiss T, Yabluchanskiy A, Csipo T, Balasubramanian P, Lipecz A, Benyo Z, Csiszar A. Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases. Geroscience. 2019 12; 41(6):727-738. PMID: 31655958.
      Citations: 59     Fields:    Translation:HumansCells
    48. Wiedenhoeft T, Tarantini S, Nyúl-Tóth Á, Yabluchanskiy A, Csipo T, Balasubramanian P, Lipecz A, Kiss T, Csiszar A, Csiszar A, Ungvari Z. Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice. Geroscience. 2019 12; 41(6):711-725. PMID: 31654270.
      Citations: 28     Fields:    Translation:Animals
    49. Csiszar A, Yabluchanskiy A, Ungvari A, Ungvari Z, Tarantini S. Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice. Geroscience. 2019 10; 41(5):609-617. PMID: 31643012.
      Citations: 38     Fields:    Translation:AnimalsCells
    50. Ungvari Z, Tarantini S, Yabluchanskiy A, Csiszar A. Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation. Front Genet. 2019; 10:898. PMID: 31616477.
      Citations: 8     
    51. Kiss T, Giles CB, Tarantini S, Yabluchanskiy A, Balasubramanian P, Gautam T, Csipo T, Nyúl-Tóth Á, Lipecz A, Szabo C, Farkas E, Wren JD, Csiszar A, Ungvari Z. Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects. Geroscience. 2019 08; 41(4):419-439. PMID: 31463647.
      Citations: 53     Fields:    Translation:Animals
    52. Tarantini S, Yabluchanskiy A, Fülöp GA, Kiss T, Perz A, O'Connor D, Johnson E, Sorond F, Ungvari ZI, Csiszar A. Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability. J Gerontol A Biol Sci Med Sci. 2019 08 16; 74(9):1417-1421. PMID: 30383221.
      Citations: 15     Fields:    Translation:HumansAnimals
    53. Czigler A, Toth L, Szarka N, Berta G, Amrein K, Czeiter E, Lendvai-Emmert D, Bodo K, Tarantini S, Koller A, Ungvari Z, Buki A, Toth P. Hypertension Exacerbates Cerebrovascular Oxidative Stress Induced by Mild Traumatic Brain Injury: Protective Effects of the Mitochondria-Targeted Antioxidative Peptide SS-31. J Neurotrauma. 2019 12 01; 36(23):3309-3315. PMID: 31266393.
      Citations: 6     Fields:    Translation:AnimalsCells
    54. Szarka N, Toth L, Czigler A, Kellermayer Z, Ungvari Z, Amrein K, Czeiter E, Bali ZK, Tadepalli SA, Wahr M, Hernadi I, Koller A, Buki A, Toth P. Single Mild Traumatic Brain Injury Induces Persistent Disruption of the Blood-Brain Barrier, Neuroinflammation and Cognitive Decline in Hypertensive Rats. Int J Mol Sci. 2019 Jun 30; 20(13). PMID: 31262044.
      Citations: 10     Fields:    Translation:Animals
    55. Lipecz A, Csipo T, Tarantini S, Hand RA, Ngo BN, Conley S, Nemeth G, Tsorbatzoglou A, Courtney DL, Yabluchanska V, Csiszar A, Ungvari ZI, Yabluchanskiy A. Age-related impairment of neurovascular coupling responses: a dynamic vessel analysis (DVA)-based approach to measure decreased flicker light stimulus-induced retinal arteriolar dilation in healthy older adults. Geroscience. 2019 06; 41(3):341-349. PMID: 31209739.
      Citations: 40     Fields:    Translation:Humans
    56. Kiss T, Balasubramanian P, Valcarcel-Ares MN, Tarantini S, Yabluchanskiy A, Csipo T, Lipecz A, Reglodi D, Zhang XA, Bari F, Farkas E, Csiszar A, Ungvari Z. Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. Geroscience. 2019 10; 41(5):619-630. PMID: 31144244.
      Citations: 66     Fields:    Translation:AnimalsCells
    57. Farias Quipildor GE, Mao K, Hu Z, Novaj A, Cui MH, Gulinello M, Branch CA, Gubbi S, Patel K, Moellering DR, Tarantini S, Kiss T, Yabluchanskiy A, Ungvari Z, Sonntag WE, Huffman DM. Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice. Geroscience. 2019 04; 41(2):185-208. PMID: 31076997.
      Citations: 44     Fields:    Translation:AnimalsCells
    58. Csiszar A, Balasubramanian P, Tarantini S, Yabluchanskiy A, Zhang XA, Springo Z, Benbrook D, Sonntag WE, Ungvari Z. Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research. Geroscience. 2019 04; 41(2):209-227. PMID: 31037472.
      Citations: 7     Fields:    Translation:HumansAnimals
    59. Csipo T, Lipecz A, Fulop GA, Hand RA, Ngo BN, Dzialendzik M, Tarantini S, Balasubramanian P, Kiss T, Yabluchanska V, Silva-Palacios F, Courtney DL, Dasari TW, Sorond F, Sonntag WE, Csiszar A, Ungvari Z, Yabluchanskiy A. Age-related decline in peripheral vascular health predicts cognitive impairment. Geroscience. 2019 04; 41(2):125-136. PMID: 31030329.
      Citations: 47     Fields:    Translation:Humans
    60. Tarantini S, Valcarcel-Ares MN, Toth P, Yabluchanskiy A, Tucsek Z, Kiss T, Hertelendy P, Kinter M, Ballabh P, Süle Z, Farkas E, Baur JA, Sinclair DA, Csiszar A, Ungvari Z. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019 06; 24:101192. PMID: 31015147.
      Citations: 122     Fields:    Translation:HumansAnimalsCells
    61. Csiszar A, Tarantini S, Yabluchanskiy A, Balasubramanian P, Kiss T, Farkas E, Baur JA, Ungvari Z. Role of endothelial NAD+ deficiency in age-related vascular dysfunction. Am J Physiol Heart Circ Physiol. 2019 06 01; 316(6):H1253-H1266. PMID: 30875255.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    62. Fulop GA, Ramirez-Perez FI, Kiss T, Tarantini S, Valcarcel Ares MN, Toth P, Yabluchanskiy A, Conley SM, Ballabh P, Martinez-Lemus LA, Ungvari Z, Csiszar A. IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging. J Gerontol A Biol Sci Med Sci. 2019 03 14; 74(4):446-454. PMID: 29931048.
      Citations: 25     Fields:    Translation:Animals
    63. Fulop GA, Tarantini S, Yabluchanskiy A, Molnar A, Prodan CI, Kiss T, Csipo T, Lipecz A, Balasubramanian P, Farkas E, Toth P, Sorond F, Csiszar A, Ungvari Z. Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment. Am J Physiol Heart Circ Physiol. 2019 05 01; 316(5):H1124-H1140. PMID: 30848677.
      Citations: 34     Fields:    Translation:HumansAnimals
    64. Valcarcel-Ares MN, Tucsek Z, Kiss T, Giles CB, Tarantini S, Yabluchanskiy A, Balasubramanian P, Gautam T, Galvan V, Ballabh P, Richardson A, Freeman WM, Wren JD, Deak F, Ungvari Z, Csiszar A. Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):290-298. PMID: 29893815.
      Citations: 42     Fields:    Translation:Animals
    65. Yabluchanskiy A, Ungvari Z, Csiszar A, Tarantini S. Advances and challenges in geroscience research: An update. Physiol Int. 2018 Dec 01; 105(4):298-308. PMID: 30587027.
      Citations: 13     Fields:    Translation:Humans
    66. Fulop GA, Kiss T, Tarantini S, Balasubramanian P, Yabluchanskiy A, Farkas E, Bari F, Ungvari Z, Csiszar A. Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation. Geroscience. 2018 12; 40(5-6):513-521. PMID: 30470983.
      Citations: 85     Fields:    Translation:Animals
    67. Ungvari Z, Yabluchanskiy A, Tarantini S, Toth P, Kirkpatrick AC, Csiszar A, Prodan CI. Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults. Geroscience. 2018 12; 40(5-6):485-496. PMID: 30288646.
      Citations: 16     Fields:    Translation:Humans
    68. Ungvari Z, Tarantini S, Donato AJ, Galvan V, Csiszar A. Mechanisms of Vascular Aging. Circ Res. 2018 09 14; 123(7):849-867. PMID: 30355080.
      Citations: 283     Fields:    Translation:HumansAnimalsCells
    69. Ungvari Z, Tarantini S, Kiss T, Wren JD, Giles CB, Griffin CT, Murfee WL, Pacher P, Csiszar A. Endothelial dysfunction and angiogenesis impairment in the ageing vasculature. Nat Rev Cardiol. 2018 09; 15(9):555-565. PMID: 29795441.
      Citations: 156     Fields:    Translation:HumansAnimals
    70. Ungvari Z, Yabluchanskiy A, Hasko G, Pacher P. Age-dependent cardiovascular effects of sepsis in a murine model of cecal ligation and puncture: implications for the design of interventional studies. Am J Physiol Heart Circ Physiol. 2018 Nov 01; 315(5):H1356-H1357. PMID: 30074837.
      Citations: 1     Fields:    Translation:Animals
    71. Reagan AM, Gu X, Paudel S, Ashpole NM, Zalles M, Sonntag WE, Ungvari Z, Csiszar A, Otalora L, Freeman WM, Stout MB, Elliott MH. Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency. Neurobiol Aging. 2018 11; 71:1-12. PMID: 30059797.
      Citations: 6     Fields:    Translation:Animals
    72. Toth P, Tarantini S, Rutkai I, Ungvari Z. Assessment of endothelial function in leptomeningeal arterioles derived from patients with Alzheimer's disease and vascular cognitive impairment. Am J Physiol Heart Circ Physiol. 2018 10 01; 315(4):H790-H793. PMID: 29932773.
      Citations:    Fields:    Translation:Humans
    73. Dohare P, Cheng B, Ahmed E, Yadala V, Singla P, Thomas S, Kayton R, Ungvari Z, Ballabh P. Glycogen synthase kinase-3ß inhibition enhances myelination in preterm newborns with intraventricular hemorrhage, but not recombinant Wnt3A. Neurobiol Dis. 2018 10; 118:22-39. PMID: 29940337.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    74. Csipo T, Fulop GA, Lipecz A, Tarantini S, Kiss T, Balasubramanian P, Csiszar A, Ungvari Z, Yabluchanskiy A. Short-term weight loss reverses obesity-induced microvascular endothelial dysfunction. Geroscience. 2018 Jun 18. PMID: 29916025.
      Citations: 31     Fields:    
    75. Tarantini S, Valcarcel-Ares MN, Yabluchanskiy A, Tucsek Z, Hertelendy P, Kiss T, Gautam T, Zhang XA, Sonntag WE, de Cabo R, Farkas E, Elliott MH, Kinter MT, Deak F, Ungvari Z, Csiszar A. Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype. J Gerontol A Biol Sci Med Sci. 2018 06 14; 73(7):853-863. PMID: 29905772.
      Citations: 74     Fields:    Translation:Animals
    76. Logan S, Owen D, Chen S, Chen WJ, Ungvari Z, Farley J, Csiszar A, Sharpe A, Loos M, Koopmans B, Richardson A, Sonntag WE. Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice. Geroscience. 2018 04; 40(2):123-137. PMID: 29687240.
      Citations: 23     Fields:    Translation:Animals
    77. Ahn B, Pharaoh G, Premkumar P, Huseman K, Ranjit R, Kinter M, Szweda L, Kiss T, Fulop G, Tarantini S, Csiszar A, Ungvari Z, Van Remmen H. Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass. Redox Biol. 2018 07; 17:47-58. PMID: 29673700.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    78. Tarantini S, Yabluchanskiy A, Fülöp GA, Hertelendy P, Noa Valcarcel-Ares M, Kiss T, Bagwell JM, O'Connor D, Farkas E, Sorond F, Csiszar A, Ungvari Z. Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice. Geroscience. 2018 04; 40(2):219. PMID: 29468558.
      Citations: 1     Fields:    
    79. Tarantini S, Valcarcel-Ares NM, Yabluchanskiy A, Fulop GA, Hertelendy P, Gautam T, Farkas E, Perz A, Rabinovitch PS, Sonntag WE, Csiszar A, Ungvari Z. Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice. Aging Cell. 2018 04; 17(2). PMID: 29405550.
      Citations: 89     Fields:    Translation:AnimalsCells
    80. Szarka N, Pabbidi MR, Amrein K, Czeiter E, Berta G, Pohoczky K, Helyes Z, Ungvari Z, Koller A, Buki A, Toth P. Traumatic Brain Injury Impairs Myogenic Constriction of Cerebral Arteries: Role of Mitochondria-Derived H2O2 and TRPV4-Dependent Activation of BKca Channels. J Neurotrauma. 2018 Apr 01; 35(7):930-939. PMID: 29179622.
      Citations: 25     Fields:    
    81. Van Skike CE, Jahrling JB, Olson AB, Sayre NL, Hussong SA, Ungvari Z, Lechleiter JD, Galvan V. Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment. Am J Physiol Heart Circ Physiol. 2018 04 01; 314(4):H693-H703. PMID: 29351469.
      Citations: 70     Fields:    Translation:AnimalsCells
    82. Tibrewal M, Cheng B, Dohare P, Hu F, Mehdizadeh R, Wang P, Zheng D, Ungvari Z, Ballabh P. Disruption of Interneuron Neurogenesis in Premature Newborns and Reversal with Estrogen Treatment. J Neurosci. 2018 01 31; 38(5):1100-1113. PMID: 29246927.
      Citations: 19     Fields:    Translation:AnimalsCells
    83. Tarantini S, Yabluchanksiy A, Fülöp GA, Hertelendy P, Valcarcel-Ares MN, Kiss T, Bagwell JM, O'Connor D, Farkas E, Sorond F, Csiszar A, Ungvari Z. Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice. Geroscience. 2017 12; 39(5-6):601-614. PMID: 29243191.
      Citations: 43     Fields:    Translation:Animals
    84. Ungvari Z, Valcarcel-Ares MN, Tarantini S, Yabluchanskiy A, Fülöp GA, Kiss T, Csiszar A. Connective tissue growth factor (CTGF) in age-related vascular pathologies. Geroscience. 2017 12; 39(5-6):491-498. PMID: 28875415.
      Citations: 35     Fields:    Translation:HumansCells
    85. Csiszar A, Tarantini S, Fülöp GA, Kiss T, Valcarcel-Ares MN, Galvan V, Ungvari Z, Yabluchanskiy A. Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease. Geroscience. 2017 Aug; 39(4):359-372. PMID: 28853030.
      Citations: 56     Fields:    
    86. Marinesco S, Ungvari Z, Galvan V. Age-related impairment of metabovascular coupling during cortical spreading depolarizations. Am J Physiol Heart Circ Physiol. 2017 12 01; 313(6):H1209-H1212. PMID: 28842440.
      Citations:    Fields:    Translation:Animals
    87. Gardner AW, Montgomery PS, Zhao YD, Ungvari Z, Csiszar A, Sonntag WE. Endothelial Cell Inflammation and Antioxidant Capacity are Associated With 6-Minute Walk Performance in Patients With Symptomatic Peripheral Artery Disease. Angiology. 2018 May; 69(5):416-423. PMID: 28835113.
      Citations: 4     Fields:    Translation:HumansCells
    88. Tucsek Z, Noa Valcarcel-Ares M, Tarantini S, Yabluchanskiy A, Fülöp G, Gautam T, Orock A, Csiszar A, Deak F, Ungvari Z. Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment. Geroscience. 2017 Aug; 39(4):385-406. PMID: 28664509.
      Citations: 46     Fields:    
    89. Zucker IH, Lindsey ML, Delmar M, De Windt LJ, Des Rosiers C, Diz DI, Hester RL, Jones SP, Kanagy NL, Kitakaze M, Liao R, Lopaschuk GD, Patel KP, Recchia FA, Sadoshima J, Shah AM, Ungvari Z, Benjamin IJ, Blaustein MP, Charkoudian N, Efimov IR, Gutterman D, Kass DA, Liao Y, O'Leary DS, Ripplinger CM, Wolin MS. Why publish in the American Journal of Physiology-Heart and Circulatory Physiology? Am J Physiol Heart Circ Physiol. 2017 08 01; 313(2):H221-H223. PMID: 28626081.
      Citations: 2     Fields:    Translation:HumansAnimals
    90. Tarantini S, Fulop GA, Kiss T, Farkas E, Zölei-Szénási D, Galvan V, Toth P, Csiszar A, Ungvari Z, Yabluchanskiy A. Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging. Geroscience. 2017 Aug; 39(4):465-473. PMID: 28578467.
      Citations: 60     Fields:    
    91. Castillo-Carranza DL, Nilson AN, Van Skike CE, Jahrling JB, Patel K, Garach P, Gerson JE, Sengupta U, Abisambra J, Nelson P, Troncoso J, Ungvari Z, Galvan V, Kayed R. Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer's Disease and Related Tauopathies. Aging Dis. 2017 May; 8(3):257-266. PMID: 28580182.
      Citations: 55     
    92. Ashpole NM, Logan S, Yabluchanskiy A, Mitschelen MC, Yan H, Farley JA, Hodges EL, Ungvari Z, Csiszar A, Chen S, Georgescu C, Hubbard GB, Ikeno Y, Sonntag WE. IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan. Geroscience. 2017 04; 39(2):129-145. PMID: 28409331.
      Citations: 82     Fields:    Translation:Animals
    93. Ungvari Z, Tarantini S, Kirkpatrick AC, Csiszar A, Prodan CI. Cerebral microhemorrhages: mechanisms, consequences, and prevention. Am J Physiol Heart Circ Physiol. 2017 Jun 01; 312(6):H1128-H1143. PMID: 28314762.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    94. Tarantini S, Valcarcel-Ares NM, Yabluchanskiy A, Springo Z, Fulop GA, Ashpole N, Gautam T, Giles CB, Wren JD, Sonntag WE, Csiszar A, Ungvari Z. Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell. 2017 06; 16(3):469-479. PMID: 28295976.
      Citations: 63     Fields:    Translation:AnimalsCells
    95. Gardner AW, Montgomery PS, Zhao YD, Silva-Palacios F, Ungvari Z, Csiszar A, Sonntag WE. Association between daily walking and antioxidant capacity in patients with symptomatic peripheral artery disease. J Vasc Surg. 2017 06; 65(6):1762-1768. PMID: 28259579.
      Citations: 12     Fields:    Translation:HumansCells
    96. Podlutsky A, Valcarcel-Ares MN, Yancey K, Podlutskaya V, Nagykaldi E, Gautam T, Miller RA, Sonntag WE, Csiszar A, Ungvari Z. The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer. Geroscience. 2017 04; 39(2):147-160. PMID: 28233247.
      Citations: 50     Fields:    Translation:AnimalsCells
    97. Ungvari Z, Tarantini S, Hertelendy P, Valcarcel-Ares MN, Fülöp GA, Logan S, Kiss T, Farkas E, Csiszar A, Yabluchanskiy A. Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence. Geroscience. 2017 02; 39(1):33-42. PMID: 28299642.
      Citations: 64     Fields:    Translation:AnimalsPHPublic Health
    98. Sonntag WE, Ungvari Z. GeroScience: understanding the interaction of processes of aging and chronic diseases. Age (Dordr). 2016 12; 38(5-6):377-378. PMID: 27924421.
      Citations: 4     Fields:    Translation:Humans
    99. Tarantini S, Tran CHT, Gordon GR, Ungvari Z, Csiszar A. Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline. Exp Gerontol. 2017 08; 94:52-58. PMID: 27845201.
      Citations: 189     Fields:    Translation:HumansAnimalsCells
    100. Toth P, Tarantini S, Csiszar A, Ungvari Z. Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging. Am J Physiol Heart Circ Physiol. 2017 Jan 01; 312(1):H1-H20. PMID: 27793855.
      Citations: 219     Fields:    Translation:Humans
    101. Tarantini S, Tucsek Z, Valcarcel-Ares MN, Toth P, Gautam T, Giles CB, Ballabh P, Wei JY, Wren JD, Ashpole NM, Sonntag WE, Ungvari Z, Csiszar A. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289. PMID: 27613724.
      Citations: 55     Fields:    Translation:HumansAnimals
    102. Toth P, Szarka N, Farkas E, Ezer E, Czeiter E, Amrein K, Ungvari Z, Hartings JA, Buki A, Koller A. Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling: Pathomechanisms, perspectives, and therapeutic implications. Am J Physiol Heart Circ Physiol. 2016 11 01; 311(5):H1118-H1131. PMID: 27614225.
      Citations: 47     Fields:    Translation:HumansAnimals
    103. Tarantini S, Giles CB, Wren JD, Ashpole NM, Valcarcel-Ares MN, Wei JY, Sonntag WE, Ungvari Z, Csiszar A. IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis. Age (Dordr). 2016 Aug; 38(4):239-258. PMID: 27566308.
      Citations: 24     Fields:    Translation:AnimalsCells
    104. Gardner AW, Montgomery PS, Casanegra AI, Silva-Palacios F, Ungvari Z, Csiszar A. Association between gait characteristics and endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease. Age (Dordr). 2016 Jun; 38(3):64. PMID: 27273077.
      Citations: 22     Fields:    Translation:Humans
    105. Alfaras I, Di Germanio C, Bernier M, Csiszar A, Ungvari Z, Lakatta EG, de Cabo R. Pharmacological Strategies to Retard Cardiovascular Aging. Circ Res. 2016 05 13; 118(10):1626-42. PMID: 27174954.
      Citations: 28     Fields:    Translation:HumansAnimals
    106. Bernier M, Wahl D, Ali A, Allard J, Faulkner S, Wnorowski A, Sanghvi M, Moaddel R, Alfaras I, Mattison JA, Tarantini S, Tucsek Z, Ungvari Z, Csiszar A, Pearson KJ, de Cabo R. Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet. Aging (Albany NY). 2016 05; 8(5):899-916. PMID: 27070252.
      Citations: 32     Fields:    Translation:Animals
    107. Dohare P, Zia MT, Ahmed E, Ahmed A, Yadala V, Schober AL, Ortega JA, Kayton R, Ungvari Z, Mongin AA, Ballabh P. AMPA-Kainate Receptor Inhibition Promotes Neurologic Recovery in Premature Rabbits with Intraventricular Hemorrhage. J Neurosci. 2016 Mar 16; 36(11):3363-77. PMID: 26985043.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    108. Gardner AW, Parker DE, Montgomery PS, Sosnowska D, Casanegra AI, Ungvari Z, Csiszar A, Zhang SX, Wang JJ, Sonntag WE. INFLUENCE OF DIABETES ON AMBULATION AND INFLAMMATION IN MEN AND WOMEN WITH SYMPTOMATIC PERIPHERAL ARTERY DISEASE. J Clin Transl Endocrinol. 2015 Dec 01; 2(4):137-143. PMID: 26835254.
      Citations: 5     
    109. Deak F, Freeman WM, Ungvari Z, Csiszar A, Sonntag WE. Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment. J Gerontol A Biol Sci Med Sci. 2016 Jan; 71(1):13-20. PMID: 26590911.
      Citations: 21     Fields:    Translation:Humans
    110. Hersch N, Wolters B, Ungvari Z, Gautam T, Deshpande D, Merkel R, Csiszar A, Hoffmann B, Csiszár A. Biotin-conjugated fusogenic liposomes for high-quality cell purification. J Biomater Appl. 2016 Jan; 30(6):846-56. PMID: 26475851.
      Citations: 6     Fields:    Translation:AnimalsCells
    111. Toth P, Tarantini S, Davila A, Valcarcel-Ares MN, Tucsek Z, Varamini B, Ballabh P, Sonntag WE, Baur JA, Csiszar A, Ungvari Z. Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex. Am J Physiol Heart Circ Physiol. 2015 Dec 01; 309(11):H1837-45. PMID: 26453330.
      Citations: 51     Fields:    Translation:AnimalsCells
    112. Ashpole NM, Herron JC, Mitschelen MC, Farley JA, Logan S, Yan H, Ungvari Z, Hodges EL, Csiszar A, Ikeno Y, Humphrey MB, Sonntag WE. IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms. J Bone Miner Res. 2016 Feb; 31(2):443-54. PMID: 26260312.
      Citations: 26     Fields:    Translation:AnimalsCells
    113. Tarantini S, Hertelendy P, Tucsek Z, Valcarcel-Ares MN, Smith N, Menyhart A, Farkas E, Hodges EL, Towner R, Deak F, Sonntag WE, Csiszar A, Ungvari Z, Toth P. Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice. J Cereb Blood Flow Metab. 2015 Nov; 35(11):1871-81. PMID: 26174328.
      Citations: 87     Fields:    Translation:Animals
    114. Toth P, Tarantini S, Ashpole NM, Tucsek Z, Milne GL, Valcarcel-Ares NM, Menyhart A, Farkas E, Sonntag WE, Csiszar A, Ungvari Z. IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging. Aging Cell. 2015 Dec; 14(6):1034-44. PMID: 26172407.
      Citations: 97     Fields:    Translation:Animals
    115. Springo Z, Toth P, Tarantini S, Ashpole NM, Tucsek Z, Sonntag WE, Csiszar A, Koller A, Ungvari ZI. Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries. J Cereb Blood Flow Metab. 2015 Mar 31; 35(4):527-30. PMID: 25605292.
      Citations: 39     Fields:    Translation:Animals
    116. Toth P, Tarantini S, Springo Z, Tucsek Z, Gautam T, Giles CB, Wren JD, Koller A, Sonntag WE, Csiszar A, Ungvari Z. Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection. Aging Cell. 2015 Jun; 14(3):400-8. PMID: 25677910.
      Citations: 85     Fields:    Translation:AnimalsCells
    117. Springo Z, Tarantini S, Toth P, Tucsek Z, Koller A, Sonntag WE, Csiszar A, Ungvari Z. Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries. J Gerontol A Biol Sci Med Sci. 2015 Nov; 70(11):1355-9. PMID: 25631392.
      Citations: 43     Fields:    Translation:AnimalsCells
    118. Gardner AW, Parker DE, Montgomery PS, Sosnowska D, Casanegra AI, Ungvari Z, Csiszar A, Sonntag WE. Endothelial Cell Inflammation and Antioxidant Capacity are Associated With Exercise Performance and Microcirculation in Patients With Symptomatic Peripheral Artery Disease. Angiology. 2015 Oct; 66(9):867-74. PMID: 25603804.
      Citations: 12     Fields:    Translation:HumansCells
    119. Ungvari Z, Sonntag WE. Brain and cerebrovascular aging--new mechanisms and insights. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1307-10. PMID: 25301834.
      Citations: 8     Fields:    Translation:HumansAnimals
    120. Toth P, Tucsek Z, Tarantini S, Sosnowska D, Gautam T, Mitschelen M, Koller A, Sonntag WE, Csiszar A, Ungvari Z. IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice. J Cereb Blood Flow Metab. 2014 Dec; 34(12):1887-97. PMID: 25248835.
      Citations: 74     Fields:    Translation:AnimalsCells
    121. Banki E, Sosnowska D, Tucsek Z, Gautam T, Toth P, Tarantini S, Tamas A, Helyes Z, Reglodi D, Sonntag WE, Csiszar A, Ungvari Z. Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2015 Jun; 70(6):665-74. PMID: 25136000.
      Citations: 28     Fields:    Translation:AnimalsCells
    122. Yan H, Mitschelen M, Toth P, Ashpole NM, Farley JA, Hodges EL, Warrington JP, Han S, Fung KM, Csiszar A, Ungvari Z, Sonntag WE. Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1353-62. PMID: 25098324.
      Citations: 9     Fields:    Translation:AnimalsCells
    123. Ashpole NM, Warrington JP, Mitschelen MC, Yan H, Sosnowska D, Gautam T, Farley JA, Csiszar A, Ungvari Z, Sonntag WE. Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells. Am J Physiol Heart Circ Physiol. 2014 Sep 15; 307(6):H858-68. PMID: 25038144.
      Citations: 13     Fields:    Translation:AnimalsCellsPHPublic Health
    124. Csiszar A, Gautam T, Sosnowska D, Tarantini S, Banki E, Tucsek Z, Toth P, Losonczy G, Koller A, Reglodi D, Giles CB, Wren JD, Sonntag WE, Ungvari Z. Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H292-306. PMID: 24906921.
      Citations: 87     Fields:    Translation:AnimalsCells
    125. Tucsek Z, Toth P, Tarantini S, Sosnowska D, Gautam T, Warrington JP, Giles CB, Wren JD, Koller A, Ballabh P, Sonntag WE, Ungvari Z, Csiszar A. Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1339-52. PMID: 24895269.
      Citations: 113     Fields:    Translation:AnimalsCells
    126. Mattison JA, Wang M, Bernier M, Zhang J, Park SS, Maudsley S, An SS, Santhanam L, Martin B, Faulkner S, Morrell C, Baur JA, Peshkin L, Sosnowska D, Csiszar A, Herbert RL, Tilmont EM, Ungvari Z, Pearson KJ, Lakatta EG, de Cabo R. Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates. Cell Metab. 2014 Jul 01; 20(1):183-90. PMID: 24882067.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    127. Gardner AW, Parker DE, Montgomery PS, Sosnowska D, Casanegra AI, Ungvari Z, Csiszar A, Sonntag WE. Greater endothelial apoptosis and oxidative stress in patients with peripheral artery disease. Int J Vasc Med. 2014; 2014:160534. PMID: 24963409.
      Citations: 17     
    128. Gardner AW, Parker DE, Montgomery PS, Sosnowska D, Casanegra AI, Ungvari Z, Csiszar A, Sonntag WE. Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease. J Vasc Surg. 2015 May; 61(5):1249-57. PMID: 24703977.
      Citations: 30     Fields:    Translation:Humans
    129. Csiszár A, Csiszar A, Pinto JT, Gautam T, Kleusch C, Hoffmann B, Tucsek Z, Toth P, Sonntag WE, Ungvari Z. Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats. J Gerontol A Biol Sci Med Sci. 2015 Mar; 70(3):303-13. PMID: 24642904.
      Citations: 31     Fields:    Translation:AnimalsCells
    130. Vimercati C, Qanud K, Mitacchione G, Sosnowska D, Ungvari Z, Sarnari R, Mania D, Patel N, Hintze TH, Gupte SA, Stanley WC, Recchia FA. Beneficial effects of acute inhibition of the oxidative pentose phosphate pathway in the failing heart. Am J Physiol Heart Circ Physiol. 2014 Mar 01; 306(5):H709-17. PMID: 24414069.
      Citations: 18     Fields:    Translation:AnimalsCells
    131. Sosnowska D, Richardson C, Sonntag WE, Csiszar A, Ungvari Z, Ridgway I. A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal. J Gerontol A Biol Sci Med Sci. 2014 Dec; 69(12):1448-61. PMID: 24347613.
      Citations: 9     Fields:    Translation:AnimalsCells
    132. Toth P, Tarantini S, Tucsek Z, Ashpole NM, Sosnowska D, Gautam T, Ballabh P, Koller A, Sonntag WE, Csiszar A, Ungvari Z. Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase. Am J Physiol Heart Circ Physiol. 2014 Feb; 306(3):H299-308. PMID: 24322615.
      Citations: 112     Fields:    Translation:Animals
    133. Tucsek Z, Toth P, Sosnowska D, Gautam T, Mitschelen M, Koller A, Szalai G, Sonntag WE, Ungvari Z, Csiszar A. Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease. J Gerontol A Biol Sci Med Sci. 2014 Oct; 69(10):1212-26. PMID: 24269929.
      Citations: 157     Fields:    Translation:Animals
    134. Toth P, Csiszar A, Tucsek Z, Sosnowska D, Gautam T, Koller A, Schwartzman ML, Sonntag WE, Ungvari Z. Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice. Am J Physiol Heart Circ Physiol. 2013 Dec; 305(12):H1698-708. PMID: 24097425.
      Citations: 55     Fields:    Translation:AnimalsCells
    135. Warrington JP, Ashpole N, Csiszar A, Lee YW, Ungvari Z, Sonntag WE. Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications. J Vasc Res. 2013; 50(6):445-57. PMID: 24107797.
      Citations: 45     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    136. Dikalov SI, Ungvari Z. Role of mitochondrial oxidative stress in hypertension. Am J Physiol Heart Circ Physiol. 2013 Nov 15; 305(10):H1417-27. PMID: 24043248.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    137. Gardner AW, Parker DE, Montgomery PS, Sosnowska D, Casanegra AI, Esponda OL, Ungvari Z, Csiszar A, Sonntag WE. Impaired vascular endothelial growth factor A and inflammation in patients with peripheral artery disease. Angiology. 2014 Sep; 65(8):683-90. PMID: 24006146.
      Citations: 29     Fields:    Translation:Humans
    138. Csiszar A, Tucsek Z, Toth P, Sosnowska D, Gautam T, Koller A, Deak F, Sonntag WE, Ungvari Z. Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in ß-amyloid generation and Alzheimer's disease. Am J Physiol Heart Circ Physiol. 2013 Oct 15; 305(8):H1120-30. PMID: 23955715.
      Citations: 35     Fields:    Translation:Animals
    139. Toth P, Tucsek Z, Sosnowska D, Gautam T, Mitschelen M, Tarantini S, Deak F, Koller A, Sonntag WE, Csiszar A, Ungvari Z. Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension. J Cereb Blood Flow Metab. 2013 Nov; 33(11):1732-42. PMID: 23942363.
      Citations: 126     Fields:    Translation:AnimalsCells
    140. Sonntag WE, Deak F, Ashpole N, Toth P, Csiszar A, Freeman W, Ungvari Z. Insulin-like growth factor-1 in CNS and cerebrovascular aging. Front Aging Neurosci. 2013; 5:27. PMID: 23847531.
      Citations: 70     
    141. Ungvari Z, Podlutsky A, Sosnowska D, Tucsek Z, Toth P, Deak F, Gautam T, Csiszar A, Sonntag WE. Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity. J Gerontol A Biol Sci Med Sci. 2013 Dec; 68(12):1443-57. PMID: 23689827.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    142. Toth P, Csiszar A, Sosnowska D, Tucsek Z, Cseplo P, Springo Z, Tarantini S, Sonntag WE, Ungvari Z, Koller A. Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats. Br J Pharmacol. 2013 Apr; 168(8):1878-88. PMID: 23194285.
      Citations: 25     Fields:    Translation:AnimalsCells
    143. Vinukonda G, Zia MT, Bhimavarapu BB, Hu F, Feinberg M, Bokhari A, Ungvari Z, Fried VA, Ballabh P. Intraventricular hemorrhage induces deposition of proteoglycans in premature rabbits, but their in vivo degradation with chondroitinase does not restore myelination, ventricle size and neurological recovery. Exp Neurol. 2013 Sep; 247:630-44. PMID: 23474192.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    144. Shi Y, Pulliam DA, Liu Y, Hamilton RT, Jernigan AL, Bhattacharya A, Sloane LB, Qi W, Chaudhuri A, Buffenstein R, Ungvari Z, Austad SN, Van Remmen H. Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus. Am J Physiol Regul Integr Comp Physiol. 2013 Mar 01; 304(5):R343-55. PMID: 23325454.
      Citations: 22     Fields:    Translation:AnimalsCells
    145. Ungvari Z, Tucsek Z, Sosnowska D, Toth P, Gautam T, Podlutsky A, Csiszar A, Losonczy G, Valcarcel-Ares MN, Sonntag WE, Csiszar A. Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2013 Aug; 68(8):877-91. PMID: 23239824.
      Citations: 76     Fields:    Translation:AnimalsCells
    146. Bailey-Downs LC, Tucsek Z, Toth P, Sosnowska D, Gautam T, Sonntag WE, Csiszar A, Ungvari Z. Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation. J Gerontol A Biol Sci Med Sci. 2013 Jul; 68(7):780-92. PMID: 23213032.
      Citations: 68     Fields:    Translation:AnimalsCells
    147. Tucsek Z, Gautam T, Sonntag WE, Toth P, Saito H, Salomao R, Szabo C, Csiszar A, Ungvari Z. Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients. J Gerontol A Biol Sci Med Sci. 2013 Jun; 68(6):652-60. PMID: 23183901.
      Citations: 24     Fields:    Translation:HumansAnimals
    148. Ungvari Z, Sosnowska D, Mason JB, Gruber H, Lee SW, Schwartz TS, Brown MK, Storm NJ, Fortney K, Sowa J, Byrne AB, Kurz T, Levy E, Sonntag WE, Austad SN, Csiszar A, Ridgway I. Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype? J Gerontol A Biol Sci Med Sci. 2013 May; 68(5):521-9. PMID: 23051979.
      Citations: 12     Fields:    Translation:Animals
    149. Ungvari Z, Csiszar A, Sosnowska D, Philipp EE, Campbell CM, McQuary PR, Chow TT, Coelho M, Didier ES, Gelino S, Holmbeck MA, Kim I, Levy E, Sonntag WE, Whitby PW, Austad SN, Ridgway I. Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa). J Gerontol A Biol Sci Med Sci. 2013 Apr; 68(4):359-67. PMID: 22904097.
      Citations: 15     Fields:    Translation:AnimalsCells
    150. Csiszar A, Sosnowska D, Tucsek Z, Gautam T, Toth P, Losonczy G, Colman RJ, Weindruch R, Anderson RM, Sonntag WE, Ungvari Z. Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells. J Gerontol A Biol Sci Med Sci. 2013 Mar; 68(3):235-49. PMID: 22904098.
      Citations: 39     Fields:    Translation:AnimalsCells
    151. Vinukonda G, Hu F, Upreti C, Ungvari Z, Zia MT, Stanton PK, Ballabh P. Novel organotypic in vitro slice culture model for intraventricular hemorrhage of premature infants. J Neurosci Res. 2012 Nov; 90(11):2173-82. PMID: 22806625.
      Citations: 2     Fields:    Translation:HumansAnimals
    152. Baur JA, Ungvari Z, Minor RK, Le Couteur DG, de Cabo R. Are sirtuins viable targets for improving healthspan and lifespan? Nat Rev Drug Discov. 2012 Jun 01; 11(6):443-61. PMID: 22653216.
      Citations: 175     Fields:    Translation:HumansAnimals
    153. Sonntag WE, Csiszar A, deCabo R, Ferrucci L, Ungvari Z. Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):587-98. PMID: 22522510.
      Citations: 47     Fields:    Translation:HumansAnimals
    154. Dai DF, Rabinovitch PS, Ungvari Z. Mitochondria and cardiovascular aging. Circ Res. 2012 Apr 13; 110(8):1109-24. PMID: 22499901.
      Citations: 184     Fields:    Translation:HumansAnimalsCells
    155. Ungvari Z, Csiszar A. The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):599-610. PMID: 22451468.
      Citations: 73     Fields:    Translation:HumansAnimals
    156. Csiszar A, Podlutsky A, Podlutskaya N, Sonntag WE, Merlin SZ, Philipp EE, Doyle K, Davila A, Recchia FA, Ballabh P, Pinto JT, Ungvari Z. Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production? J Gerontol A Biol Sci Med Sci. 2012 Aug; 67(8):841-52. PMID: 22219516.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    157. Csiszar A, Sosnowska D, Wang M, Lakatta EG, Sonntag WE, Ungvari Z. Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment. J Gerontol A Biol Sci Med Sci. 2012 Aug; 67(8):811-20. PMID: 22219513.
      Citations: 87     Fields:    Translation:AnimalsCells
    158. Valcarcel-Ares MN, Gautam T, Warrington JP, Bailey-Downs L, Sosnowska D, de Cabo R, Losonczy G, Sonntag WE, Ungvari Z, Csiszar A. Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging. J Gerontol A Biol Sci Med Sci. 2012 Aug; 67(8):821-9. PMID: 22219515.
      Citations: 86     Fields:    Translation:HumansCells
    159. Bailey-Downs LC, Sosnowska D, Toth P, Mitschelen M, Gautam T, Henthorn JC, Ballabh P, Koller A, Farley JA, Sonntag WE, Csiszar A, Ungvari Z. Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):553-64. PMID: 22080499.
      Citations: 50     Fields:    Translation:Animals
    160. Bailey-Downs LC, Mitschelen M, Sosnowska D, Toth P, Pinto JT, Ballabh P, Valcarcel-Ares MN, Farley J, Koller A, Henthorn JC, Bass C, Sonntag WE, Ungvari Z, Csiszar A. Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging. J Gerontol A Biol Sci Med Sci. 2012 Apr; 67(4):313-29. PMID: 22021391.
      Citations: 103     Fields:    Translation:Animals
    161. Minor RK, Baur JA, Gomes AP, Ward TM, Csiszar A, Mercken EM, Abdelmohsen K, Shin YK, Canto C, Scheibye-Knudsen M, Krawczyk M, Irusta PM, Martín-Montalvo A, Hubbard BP, Zhang Y, Lehrmann E, White AA, Price NL, Swindell WR, Pearson KJ, Becker KG, Bohr VA, Gorospe M, Egan JM, Talan MI, Auwerx J, Westphal CH, Ellis JL, Ungvari Z, Vlasuk GP, Elliott PJ, Sinclair DA, de Cabo R. SRT1720 improves survival and healthspan of obese mice. Sci Rep. 2011; 1:70. PMID: 22355589.
      Citations: 151     Fields:    Translation:Animals
    162. Ungvari Z, Sonntag WE, de Cabo R, Baur JA, Csiszar A. Mitochondrial protection by resveratrol. Exerc Sport Sci Rev. 2011 Jul; 39(3):128-32. PMID: 21383627.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    163. Ungvari Z, Bailey-Downs L, Gautam T, Sosnowska D, Wang M, Monticone RE, Telljohann R, Pinto JT, de Cabo R, Sonntag WE, Lakatta EG, Csiszar A. Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. J Gerontol A Biol Sci Med Sci. 2011 Aug; 66(8):866-75. PMID: 21622983.
      Citations: 118     Fields:    Translation:AnimalsCells
    164. Ungvari Z, Bailey-Downs L, Sosnowska D, Gautam T, Koncz P, Losonczy G, Ballabh P, de Cabo R, Sonntag WE, Csiszar A. Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H363-72. PMID: 21602469.
      Citations: 133     Fields:    Translation:Animals
    165. Mitschelen M, Yan H, Farley JA, Warrington JP, Han S, Hereñú CB, Csiszar A, Ungvari Z, Bailey-Downs LC, Bass CE, Sonntag WE. Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression. Neuroscience. 2011 Jun 30; 185:50-60. PMID: 21524689.
      Citations: 45     Fields:    Translation:AnimalsCells
    166. Ungvari Z, Ridgway I, Philipp EE, Campbell CM, McQuary P, Chow T, Coelho M, Didier ES, Gelino S, Holmbeck MA, Kim I, Levy E, Sosnowska D, Sonntag WE, Austad SN, Csiszar A. Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal. J Gerontol A Biol Sci Med Sci. 2011 Jul; 66(7):741-50. PMID: 21486920.
      Citations: 46     Fields:    Translation:Animals
    167. Ungvari Z, Csiszar A. Resveratrol confers endothelial protection in insulin-dependent diabetes mellitus: editorial to: "Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits" by F. Akar et al. Cardiovasc Drugs Ther. 2011 Apr; 25(2):111-3. PMID: 20938804.
      Citations: 7     Fields:    Translation:Animals
    168. Ungvari Z, Sosnowska D, Podlutsky A, Koncz P, Sonntag WE, Csiszar A. Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment. J Gerontol A Biol Sci Med Sci. 2011 May; 66(5):501-10. PMID: 21350246.
      Citations: 30     Fields:    Translation:AnimalsCells
    169. Ungvari Z, Bailey-Downs L, Gautam T, Jimenez R, Losonczy G, Zhang C, Ballabh P, Recchia FA, Wilkerson DC, Sonntag WE, Pearson K, de Cabo R, Csiszar A. Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia. Am J Physiol Heart Circ Physiol. 2011 Apr; 300(4):H1133-40. PMID: 21217061.
      Citations: 96     Fields:    Translation:AnimalsCells
    170. Ungvari Z, Philipp EE. Comparative gerontology--from mussels to man. J Gerontol A Biol Sci Med Sci. 2011 Mar; 66(3):295-7. PMID: 21059837.
      Citations: 10     Fields:    Translation:HumansAnimals
    171. Ungvari Z, Sonntag WE, Csiszar A. Mitochondria and aging in the vascular system. J Mol Med (Berl). 2010 Oct; 88(10):1021-7. PMID: 20714704.
      Citations: 39     Fields:    Translation:HumansCells
    172. Ungvari Z, Gautam T, Koncz P, Henthorn JC, Pinto JT, Ballabh P, Yan H, Mitschelen M, Farley J, Sonntag WE, Csiszar A. Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats. J Gerontol A Biol Sci Med Sci. 2010 Nov; 65(11):1145-56. PMID: 20713653.
      Citations: 38     Fields:    Translation:Animals
    173. Zhang H, Morgan B, Potter BJ, Ma L, Dellsperger KC, Ungvari Z, Zhang C. Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: in vivo demonstration with magnetic resonance imaging. Am J Physiol Heart Circ Physiol. 2010 Oct; 299(4):H985-94. PMID: 20675566.
      Citations: 48     Fields:    Translation:Animals
    174. Gupte S, Labinskyy N, Gupte R, Csiszar A, Ungvari Z, Edwards JG. Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM. PLoS One. 2010 Jul 26; 5(7):e11800. PMID: 20668682.
      Citations: 17     Fields:    Translation:Animals
    175. Vinukonda G, Dummula K, Malik S, Hu F, Thompson CI, Csiszar A, Ungvari Z, Ballabh P. Effect of prenatal glucocorticoids on cerebral vasculature of the developing brain. Stroke. 2010 Aug; 41(8):1766-73. PMID: 20616316.
      Citations: 39     Fields:    Translation:HumansAnimals
    176. Ungvari Z, Kaley G, de Cabo R, Sonntag WE, Csiszar A. Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci. 2010 Oct; 65(10):1028-41. PMID: 20576649.
      Citations: 235     Fields:    Translation:HumansAnimalsCells
    177. Vinukonda G, Csiszar A, Hu F, Dummula K, Pandey NK, Zia MT, Ferreri NR, Ungvari Z, LaGamma EF, Ballabh P. Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition. Brain. 2010 Aug; 133(Pt 8):2264-80. PMID: 20488889.
      Citations: 35     Fields:    Translation:AnimalsCells
    178. Pepe M, Mamdani M, Zentilin L, Csiszar A, Qanud K, Zacchigna S, Ungvari Z, Puligadda U, Moimas S, Xu X, Edwards JG, Hintze TH, Giacca M, Recchia FA. Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy. Circ Res. 2010 Jun 25; 106(12):1893-903. PMID: 20431055.
      Citations: 39     Fields:    Translation:AnimalsCells
    179. Ungvari Z, Bagi Z, Feher A, Recchia FA, Sonntag WE, Pearson K, de Cabo R, Csiszar A. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol. 2010 Jul; 299(1):H18-24. PMID: 20418481.
      Citations: 246     Fields:    Translation:HumansAnimalsCells
    180. Chua CO, Vinukonda G, Hu F, Labinskyy N, Zia MT, Pinto J, Csiszar A, Ungvari Z, Ballabh P. Effect of hyperoxic resuscitation on propensity of germinal matrix haemorrhage and cerebral injury. Neuropathol Appl Neurobiol. 2010 Aug; 36(5):448-58. PMID: 20408959.
      Citations: 3     Fields:    Translation:HumansAnimals
    181. Feher A, Rutkai I, Beleznai T, Ungvari Z, Csiszar A, Edes I, Bagi Z. Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity. Cardiovasc Res. 2010 Sep 01; 87(4):732-9. PMID: 20299334.
      Citations: 18     Fields:    Translation:Animals
    182. Ungvari Z, Labinskyy N, Mukhopadhyay P, Pinto JT, Bagi Z, Ballabh P, Zhang C, Pacher P, Csiszar A. Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells. Am J Physiol Heart Circ Physiol. 2009 Nov; 297(5):H1876-81. PMID: 19749157.
      Citations: 159     Fields:    Translation:HumansCells
    183. Chua CO, Chahboune H, Braun A, Dummula K, Chua CE, Yu J, Ungvari Z, Sherbany AA, Hyder F, Ballabh P. Consequences of intraventricular hemorrhage in a rabbit pup model. Stroke. 2009 Oct; 40(10):3369-77. PMID: 19661479.
      Citations: 52     Fields:    Translation:AnimalsCells
    184. Csiszar A, Labinskyy N, Olson S, Pinto JT, Gupte S, Wu JM, Hu F, Ballabh P, Podlutsky A, Losonczy G, de Cabo R, Mathew R, Wolin MS, Ungvari Z. Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats. Hypertension. 2009 Sep; 54(3):668-75. PMID: 19597040.
      Citations: 90     Fields:    Translation:AnimalsCells
    185. Csiszar A, Lehoux S, Ungvari Z. Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression. Antioxid Redox Signal. 2009 Jul; 11(7):1683-97. PMID: 19320562.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    186. Csiszar A, Labinskyy N, Jimenez R, Pinto JT, Ballabh P, Losonczy G, Pearson KJ, de Cabo R, Ungvari Z. Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. Mech Ageing Dev. 2009 Aug; 130(8):518-27. PMID: 19549533.
      Citations: 125     Fields:    Translation:AnimalsCells
    187. Zhang H, Zhang J, Ungvari Z, Zhang C. Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress. Arterioscler Thromb Vasc Biol. 2009 Aug; 29(8):1164-71. PMID: 19478208.
      Citations: 95     Fields:    Translation:Animals
    188. Csiszar A, Labinskyy N, Pinto JT, Ballabh P, Zhang H, Losonczy G, Pearson K, de Cabo R, Pacher P, Zhang C, Ungvari Z. Resveratrol induces mitochondrial biogenesis in endothelial cells. Am J Physiol Heart Circ Physiol. 2009 Jul; 297(1):H13-20. PMID: 19429820.
      Citations: 200     Fields:    Translation:AnimalsCells
    189. Zia MT, Csiszar A, Labinskyy N, Hu F, Vinukonda G, LaGamma EF, Ungvari Z, Ballabh P. Oxidative-nitrosative stress in a rabbit pup model of germinal matrix hemorrhage: role of NAD(P)H oxidase. Stroke. 2009 Jun; 40(6):2191-8. PMID: 19372442.
      Citations: 18     Fields:    Translation:Animals
    190. Gupte RS, Floyd BC, Kozicky M, George S, Ungvari ZI, Neito V, Wolin MS, Gupte SA. Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver. Free Radic Biol Med. 2009 Aug 01; 47(3):219-28. PMID: 19230846.
      Citations: 45     Fields:    Translation:AnimalsCells
    191. Labinskyy N, Mukhopadhyay P, Toth J, Szalai G, Veres M, Losonczy G, Pinto JT, Pacher P, Ballabh P, Podlutsky A, Austad SN, Csiszar A, Ungvari Z. Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus. Am J Physiol Heart Circ Physiol. 2009 Apr; 296(4):H946-56. PMID: 19181967.
      Citations: 32     Fields:    Translation:AnimalsCells
    192. Csiszar A, Podlutsky A, Wolin MS, Losonczy G, Pacher P, Ungvari Z. Oxidative stress and accelerated vascular aging: implications for cigarette smoking. Front Biosci (Landmark Ed). 2009 01 01; 14(8):3128-44. PMID: 19273262.
      Citations: 72     Fields:    Translation:HumansCells
    193. Addabbo F, Ratliff B, Park HC, Kuo MC, Ungvari Z, Csiszar A, Ciszar A, Krasnikov B, Krasnikof B, Sodhi K, Zhang F, Nasjletti A, Goligorsky MS. The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. Am J Pathol. 2009 Jan; 174(1):34-43. PMID: 19095954.
      Citations: 44     Fields:    Translation:AnimalsCells
    194. Csiszar A, Labinskyy N, Perez V, Recchia FA, Podlutsky A, Mukhopadhyay P, Losonczy G, Pacher P, Austad SN, Bartke A, Ungvari Z. Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice. Am J Physiol Heart Circ Physiol. 2008 Nov; 295(5):H1882-94. PMID: 18757483.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    195. Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK, Perez E, Jamieson HA, Zhang Y, Dunn SR, Sharma K, Pleshko N, Woollett LA, Csiszar A, Ikeno Y, Le Couteur D, Elliott PJ, Becker KG, Navas P, Ingram DK, Wolf NS, Ungvari Z, Sinclair DA, de Cabo R. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 2008 Aug; 8(2):157-68. PMID: 18599363.
      Citations: 518     Fields:    Translation:AnimalsCells
    196. Csiszar A, Ungvari Z. Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-alpha signaling. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H475-6. PMID: 18599592.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    197. Csiszar A, Wang M, Lakatta EG, Ungvari Z. Inflammation and endothelial dysfunction during aging: role of NF-kappaB. J Appl Physiol (1985). 2008 Oct; 105(4):1333-41. PMID: 18599677.
      Citations: 198     Fields:    Translation:HumansAnimalsCells
    198. Ungvari Z, Krasnikov BF, Csiszar A, Labinskyy N, Mukhopadhyay P, Pacher P, Cooper AJ, Podlutskaya N, Austad SN, Podlutsky A. Testing hypotheses of aging in long-lived mice of the genus Peromyscus: association between longevity and mitochondrial stress resistance, ROS detoxification pathways, and DNA repair efficiency. Age (Dordr). 2008 Sep; 30(2-3):121-33. PMID: 19424862.
      Citations: 27     Fields:    
    199. Csiszar A, Labinskyy N, Jo H, Ballabh P, Ungvari Z. Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H569-77. PMID: 18539760.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    200. Xu H, Hu F, Sado Y, Ninomiya Y, Borza DB, Ungvari Z, Lagamma EF, Csiszar A, Nedergaard M, Ballabh P. Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone. J Neurosci Res. 2008 May 15; 86(7):1482-500. PMID: 18214989.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    201. Ungvari Z, Buffenstein R, Austad SN, Podlutsky A, Kaley G, Csiszar A. Oxidative stress in vascular senescence: lessons from successfully aging species. Front Biosci. 2008 May 01; 13:5056-70. PMID: 18508570.
      Citations: 45     Fields:    Translation:HumansAnimals
    202. Csiszar A, Labinskyy N, Podlutsky A, Kaminski PM, Wolin MS, Zhang C, Mukhopadhyay P, Pacher P, Hu F, de Cabo R, Ballabh P, Ungvari Z. Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol. 2008 Jun; 294(6):H2721-35. PMID: 18424637.
      Citations: 113     Fields:    Translation:AnimalsCells
    203. Ungvari Z, Parrado-Fernandez C, Csiszar A, de Cabo R. Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circ Res. 2008 Mar 14; 102(5):519-28. PMID: 18340017.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    204. Ungvari Z, Labinskyy N, Gupte S, Chander PN, Edwards JG, Csiszar A. Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats. Am J Physiol Heart Circ Physiol. 2008 May; 294(5):H2121-8. PMID: 18326800.
      Citations: 96     Fields:    Translation:AnimalsCells
    205. Pearson KJ, Lewis KN, Price NL, Chang JW, Perez E, Cascajo MV, Tamashiro KL, Poosala S, Csiszar A, Ungvari Z, Kensler TW, Yamamoto M, Egan JM, Longo DL, Ingram DK, Navas P, de Cabo R. Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2325-30. PMID: 18287083.
      Citations: 109     Fields:    Translation:Animals
    206. Braun A, Xu H, Hu F, Kocherlakota P, Siegel D, Chander P, Ungvari Z, Csiszar A, Nedergaard M, Ballabh P. Paucity of pericytes in germinal matrix vasculature of premature infants. J Neurosci. 2007 Oct 31; 27(44):12012-24. PMID: 17978043.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    207. Csiszar A, Labinskyy N, Zhao X, Hu F, Serpillon S, Huang Z, Ballabh P, Levy RJ, Hintze TH, Wolin MS, Austad SN, Podlutsky A, Ungvari Z. Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity. Aging Cell. 2007 Dec; 6(6):783-97. PMID: 17925005.
      Citations: 63     Fields:    Translation:AnimalsCells
    208. Ungvari ZI. Endothelium-derived bone morphogenic protein antagonists may counteract the proatherogenic vascular effects of bone morphogenic protein 4. Circulation. 2007 Sep 11; 116(11):1221-3. PMID: 17846341.
      Citations: 3     Fields:    Translation:HumansAnimals
    209. Rajesh M, Mukhopadhyay P, Bátkai S, Haskó G, Liaudet L, Huffman JW, Csiszar A, Ungvari Z, Mackie K, Chatterjee S, Pacher P. CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. Am J Physiol Heart Circ Physiol. 2007 Oct; 293(4):H2210-8. PMID: 17660390.
      Citations: 122     Fields:    Translation:HumansAnimalsCells
    210. Stef G, Csiszar A, Ziangmin Z, Ferdinandy P, Ungvari Z, Veress G. Inhibition of NAD(P)H oxidase attenuates aggregation of platelets from high-risk cardiac patients with aspirin resistance. Pharmacol Rep. 2007 Jul-Aug; 59(4):428-36. PMID: 17901572.
      Citations: 4     Fields:    Translation:Humans
    211. Csiszar A, Labinskyy N, Orosz Z, Xiangmin Z, Buffenstein R, Ungvari Z. Vascular aging in the longest-living rodent, the naked mole rat. Am J Physiol Heart Circ Physiol. 2007 Aug; 293(2):H919-27. PMID: 17468332.
      Citations: 59     Fields:    Translation:Animals
    212. Ungvari Z, Orosz Z, Labinskyy N, Rivera A, Xiangmin Z, Smith K, Csiszar A. Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H37-47. PMID: 17416599.
      Citations: 162     Fields:    Translation:AnimalsCells
    213. Ballabh P, Xu H, Hu F, Braun A, Smith K, Rivera A, Lou N, Ungvari Z, Goldman SA, Csiszar A, Nedergaard M. Angiogenic inhibition reduces germinal matrix hemorrhage. Nat Med. 2007 Apr; 13(4):477-85. PMID: 17401377.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    214. Csiszar A, Toth J, Peti-Peterdi J, Ungvari Z. The aging kidney: role of endothelial oxidative stress and inflammation. Acta Physiol Hung. 2007 Mar; 94(1-2):107-15. PMID: 17444279.
      Citations: 22     Fields:    Translation:HumansAnimals
    215. Csiszar A, Labinskyy N, Smith KE, Rivera A, Bakker EN, Jo H, Gardner J, Orosz Z, Ungvari Z. Downregulation of bone morphogenetic protein 4 expression in coronary arterial endothelial cells: role of shear stress and the cAMP/protein kinase A pathway. Arterioscler Thromb Vasc Biol. 2007 Apr; 27(4):776-82. PMID: 17272757.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    216. Ungvari Z, Orosz Z, Rivera A, Labinskyy N, Xiangmin Z, Olson S, Podlutsky A, Csiszar A. Resveratrol increases vascular oxidative stress resistance. Am J Physiol Heart Circ Physiol. 2007 May; 292(5):H2417-24. PMID: 17220179.
      Citations: 100     Fields:    Translation:AnimalsCells
    217. Csiszar A, Labinskyy N, Smith K, Rivera A, Orosz Z, Ungvari Z. Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. Am J Pathol. 2007 Jan; 170(1):388-98. PMID: 17200210.
      Citations: 116     Fields:    Translation:AnimalsCells
    218. Orosz Z, Csiszar A, Labinskyy N, Smith K, Kaminski PM, Ferdinandy P, Wolin MS, Rivera A, Ungvari Z. Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation. Am J Physiol Heart Circ Physiol. 2007 Jan; 292(1):H130-9. PMID: 17213480.
      Citations: 75     Fields:    Translation:AnimalsCells
    219. Labinskyy N, Csiszar A, Orosz Z, Smith K, Rivera A, Buffenstein R, Ungvari Z. Comparison of endothelial function, O2-* and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice. Am J Physiol Heart Circ Physiol. 2006 Dec; 291(6):H2698-704. PMID: 17090784.
      Citations: 50     Fields:    Translation:Animals
    220. Csiszar A, Smith K, Labinskyy N, Orosz Z, Rivera A, Ungvari Z. Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition. Am J Physiol Heart Circ Physiol. 2006 Oct; 291(4):H1694-9. PMID: 16973825.
      Citations: 118     Fields:    Translation:HumansCells
    221. Stef G, Csiszar A, Lerea K, Ungvari Z, Veress G. Resveratrol inhibits aggregation of platelets from high-risk cardiac patients with aspirin resistance. J Cardiovasc Pharmacol. 2006 Aug; 48(2):1-5. PMID: 16954814.
      Citations: 25     Fields:    Translation:Humans
    222. Ungvari Z, Wolin MS, Csiszar A. Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling? Antioxid Redox Signal. 2006 Jul-Aug; 8(7-8):1121-9. PMID: 16910760.
      Citations: 28     Fields:    Translation:AnimalsCells
    223. Csiszar A, Labinskyy N, Orosz Z, Ungvari Z. Altered mitochondrial energy metabolism may play a role in vascular aging. Med Hypotheses. 2006; 67(4):904-8. PMID: 16750895.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    224. Wang Z, Chen Y, Labinskyy N, Hsieh TC, Ungvari Z, Wu JM. Regulation of proliferation and gene expression in cultured human aortic smooth muscle cells by resveratrol and standardized grape extracts. Biochem Biophys Res Commun. 2006 Jul 21; 346(1):367-76. PMID: 16759640.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    225. Csiszar A, Ahmad M, Smith KE, Labinskyy N, Gao Q, Kaley G, Edwards JG, Wolin MS, Ungvari Z. Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. Am J Pathol. 2006 Feb; 168(2):629-38. PMID: 16436676.
      Citations: 72     Fields:    Translation:AnimalsCells
    226. Labinskyy N, Csiszar A, Veress G, Stef G, Pacher P, Oroszi G, Wu J, Ungvari Z. Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen. Curr Med Chem. 2006; 13(9):989-96. PMID: 16611080.
      Citations: 56     Fields:    Translation:Humans
    227. Csiszar A, Pacher P, Kaley G, Ungvari Z. Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. Curr Vasc Pharmacol. 2005 Jul; 3(3):285-91. PMID: 16026324.
      Citations: 37     Fields:    Translation:HumansAnimals
    228. Csiszar A, Smith KE, Koller A, Kaley G, Edwards JG, Ungvari Z. Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure. Circulation. 2005 May 10; 111(18):2364-72. PMID: 15851600.
      Citations: 90     Fields:    Translation:HumansAnimals
    229. Ungvari Z, Csiszar A, Kaley G. Vascular inflammation in aging. Herz. 2004 Dec; 29(8):733-40. PMID: 15599669.
      Citations: 37     Fields:    Translation:HumansAnimals
    230. Ungvari Z, Csiszar A, Kaminski PM, Wolin MS, Koller A. Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. Am J Pathol. 2004 Jul; 165(1):219-26. PMID: 15215177.
      Citations: 42     Fields:    Translation:Animals
    231. Csiszar A, Ungvari Z, Koller A, Edwards JG, Kaley G. Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging. Physiol Genomics. 2004 Mar 12; 17(1):21-30. PMID: 15020720.
      Citations: 95     Fields:    Translation:AnimalsCells
    232. Csiszar A, Ungvari Z. Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery disease. Med Hypotheses. 2004; 63(4):696-8. PMID: 15325020.
      Citations: 11     Fields:    Translation:HumansAnimals
    233. Gupte SA, Arshad M, Viola S, Kaminski PM, Ungvari Z, Rabbani G, Koller A, Wolin MS. Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries. Am J Physiol Heart Circ Physiol. 2003 Dec; 285(6):H2316-26. PMID: 12933338.
      Citations: 31     Fields:    Translation:AnimalsCells
    234. Ungvari Z, Csiszar A, Huang A, Kaminski PM, Wolin MS, Koller A. High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase. Circulation. 2003 Sep 09; 108(10):1253-8. PMID: 12874194.
      Citations: 85     Fields:    Translation:AnimalsCells
    235. Csiszar A, Ungvari Z, Koller A, Edwards JG, Kaley G. Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries. FASEB J. 2003 Jun; 17(9):1183-5. PMID: 12709402.
      Citations: 111     Fields:    Translation:HumansAnimals
    236. Ungvari Z, Csiszar A, Edwards JG, Kaminski PM, Wolin MS, Kaley G, Koller A. Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase. Arterioscler Thromb Vasc Biol. 2003 Mar 01; 23(3):418-24. PMID: 12615666.
      Citations: 80     Fields:    Translation:AnimalsCells
    237. Massett MP, Ungvari Z, Csiszar A, Kaley G, Koller A. Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists. Am J Physiol Heart Circ Physiol. 2002 Dec; 283(6):H2282-7. PMID: 12427592.
      Citations: 23     Fields:    Translation:Animals
    238. Ungvari Z, Csiszar A, Bagi Z, Koller A. Impaired nitric oxide-mediated flow-induced coronary dilation in hyperhomocysteinemia: morphological and functional evidence for increased peroxynitrite formation. Am J Pathol. 2002 Jul; 161(1):145-53. PMID: 12107099.
      Citations: 18     Fields:    Translation:Animals
    239. Csiszar A, Ungvari Z, Edwards JG, Kaminski P, Wolin MS, Koller A, Kaley G. Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res. 2002 Jun 14; 90(11):1159-66. PMID: 12065318.
      Citations: 233     Fields:    Translation:Animals
    240. Csiszar A, Stef G, Pacher P, Ungvari Z. Oxidative stress-induced isoprostane formation may contribute to aspirin resistance in platelets. Prostaglandins Leukot Essent Fatty Acids. 2002 May-Jun; 66(5-6):557-8. PMID: 12144879.
      Citations: 6     Fields:    Translation:HumansCells
    241. Ungvari Z, Csiszar A, Koller A. Increases in endothelial Ca(2+) activate K(Ca) channels and elicit EDHF-type arteriolar dilation via gap junctions. Am J Physiol Heart Circ Physiol. 2002 May; 282(5):H1760-7. PMID: 11959641.
      Citations: 23     Fields:    Translation:AnimalsCells
    242. Pacher P, Ungvari Z. Use of selective serotonin reuptake inhibitors and myocardial infarction. Circulation. 2002 Apr 09; 105(14):e84. PMID: 11940561.
      Citations: 2     Fields:    Translation:Humans
    243. Bagi Z, Ungvari Z, Koller A. Xanthine oxidase-derived reactive oxygen species convert flow-induced arteriolar dilation to constriction in hyperhomocysteinemia: possible role of peroxynitrite. Arterioscler Thromb Vasc Biol. 2002 Jan; 22(1):28-33. PMID: 11788457.
      Citations: 22     Fields:    Translation:Animals
    244. Ungvari Z, Pacher P, Csiszar A. Can simvastatin promote tumor growth by inducing angiogenesis similar to VEGF? Med Hypotheses. 2002 Jan; 58(1):85-6. PMID: 11863404.
      Citations: 2     Fields:    Translation:Humans
    245. Ungvari Z, Brown G, Venuto R, Koller A, Losonczy G. Increased NO-mediated and reduced TxA2-dependent responses in skeletal muscle arterioles in pregnancy. Hypertens Pregnancy. 2002; 21(2):135-46. PMID: 12175442.
      Citations: 2     Fields:    Translation:AnimalsCells
    246. Pacher P, Ungvari Z. Selective serotonin-reuptake inhibitor antidepressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels. Med Hypotheses. 2001 Oct; 57(4):469-71. PMID: 11601871.
      Citations: 21     Fields:    Translation:Humans
    247. Ungvari Z, Koller A. Mediation of EDHF-induced reduction of smooth muscle [Ca(2+)](i) and arteriolar dilation by K(+) channels, 5,6-EET, and gap junctions. Microcirculation. 2001 Aug; 8(4):265-74. PMID: 11528534.
      Citations: 5     Fields:    Translation:AnimalsCells
    248. Ungvari Z, Sun D, Huang A, Kaley G, Koller A. Role of endothelial [Ca2+]i in activation of eNOS in pressurized arterioles by agonists and wall shear stress. Am J Physiol Heart Circ Physiol. 2001 Aug; 281(2):H606-12. PMID: 11454563.
      Citations: 18     Fields:    Translation:AnimalsCells
    249. Pacher P, Ungvari Z, Kecskeméti V, Friedmann T, Furst S. Serotonin reuptake inhibitors fluoxetine and citalopram relax intestinal smooth muscle. Can J Physiol Pharmacol. 2001 Jul; 79(7):580-4. PMID: 11478591.
      Citations: 4     Fields:    Translation:Animals
    250. Ungvari Z, Koller A. Selected contribution: NO released to flow reduces myogenic tone of skeletal muscle arterioles by decreasing smooth muscle Ca(2+) sensitivity. J Appl Physiol (1985). 2001 Jul; 91(1):522-7; discussion 504-5. PMID: 11408472.
      Citations: 9     Fields:    Translation:Animals
    251. Ungvari Z, Koller A. Homocysteine reduces smooth muscle [Ca2+]i and constrictor responses of isolated arterioles. J Cardiovasc Pharmacol. 2001 Jun; 37(6):705-12. PMID: 11392467.
      Citations:    Fields:    Translation:AnimalsCells
    252. Bagi Z, Ungvari Z, Szollár L, Koller A. Flow-induced constriction in arterioles of hyperhomocysteinemic rats is due to impaired nitric oxide and enhanced thromboxane A(2) mediation. Arterioscler Thromb Vasc Biol. 2001 Feb; 21(2):233-7. PMID: 11156858.
      Citations: 15     Fields:    Translation:Animals
    253. Ungvari Z, Koller A. Endothelin and prostaglandin H(2)/thromboxane A(2) enhance myogenic constriction in hypertension by increasing Ca(2+) sensitivity of arteriolar smooth muscle. Hypertension. 2000 Nov; 36(5):856-61. PMID: 11082156.
      Citations: 14     Fields:    Translation:Animals
    254. Ungvari Z, Pacher P, Koller A. Serotonin reuptake inhibitor fluoxetine decreases arteriolar myogenic tone by reducing smooth muscle [Ca2+]i. J Cardiovasc Pharmacol. 2000 Jun; 35(6):849-54. PMID: 10836717.
      Citations: 15     Fields:    Translation:Animals
    255. Ungvari Z, Sarkadi-Nagy E, Bagi Z, Szollár L, Koller A. Simultaneously increased TxA(2) activity in isolated arterioles and platelets of rats with hyperhomocysteinemia. Arterioscler Thromb Vasc Biol. 2000 May; 20(5):1203-8. PMID: 10807734.
      Citations: 13     Fields:    Translation:AnimalsCells
    256. Ungvari Z, Pacher P, Kecskeméti V, Koller A. Fluoxetine dilates isolated small cerebral arteries of rats and attenuates constrictions to serotonin, norepinephrine, and a voltage-dependent Ca(2+) channel opener. Stroke. 1999 Sep; 30(9):1949-54. PMID: 10471449.
      Citations: 22     Fields:    Translation:Animals
    257. Ungvari Z, Pacher P, Kecskemeti V, Papp G, Szollár L, Koller A. Increased myogenic tone in skeletal muscle arterioles of diabetic rats. Possible role of increased activity of smooth muscle Ca2+ channels and protein kinase C. Cardiovasc Res. 1999 Sep; 43(4):1018-28. PMID: 10615429.
      Citations: 30     Fields:    Translation:AnimalsCells
    258. Ungvari Z, Pacher P, Rischák K, Szollár L, Koller A. Dysfunction of nitric oxide mediation in isolated rat arterioles with methionine diet-induced hyperhomocysteinemia. Arterioscler Thromb Vasc Biol. 1999 Aug; 19(8):1899-904. PMID: 10446068.
      Citations: 18     Fields:    Translation:Animals
    259. Pacher P, Ungvari Z, Kecskemeti V, Koller A. Serotonin reuptake inhibitor, fluoxetine, dilates isolated skeletal muscle arterioles. Possible role of altered Ca2+ sensitivity. Br J Pharmacol. 1999 Jun; 127(3):740-6. PMID: 10401565.
      Citations: 10     Fields:    Translation:Animals
    260. Pacher P, Ungvari Z, Nanasi PP, Furst S, Kecskemeti V. Speculations on difference between tricyclic and selective serotonin reuptake inhibitor antidepressants on their cardiac effects. Is there any? Curr Med Chem. 1999 Jun; 6(6):469-80. PMID: 10213794.
      Citations: 24     Fields:    Translation:HumansAnimals
    261. Pacher P, Ungvari Z, Kecskemeti V. Electrophysiological effects of homocysteine in isolated rat right ventricular papillary muscles and left atria. Gen Pharmacol. 1999 Apr; 32(4):439-43. PMID: 10323484.
      Citations: 2     Fields:    Translation:Animals
    262. Pacher P, Ungvari Z, Kecskemeti V, Furst S. Review of cardiovascular effects of fluoxetine, a selective serotonin reuptake inhibitor, compared to tricyclic antidepressants. Curr Med Chem. 1998 Oct; 5(5):381-90. PMID: 9756980.
      Citations: 9     Fields:    Translation:HumansAnimals
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