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Randle M Gallucci

InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentPharmaceutical Sciences
AddressCPB 333
1110 N Stonewall Ave
Oklahoma City OK 73117
Phone405/271-6593 ext 47188
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    Collapse Research 
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    F31AA005382     (GALLUCCI, RANDLE MICHAEL)Oct 22, 1994
    Role: Principal Investigator

    R01GM067745     (GALLUCCI, RANDLE MICHAEL)May 1, 2004 - Oct 30, 2009
    Identification of an IL-6 induced keratinocyte motogen
    Role: Principal Investigator

    R03AA015198     (GALLUCCI, RANDLE MICHAEL)Apr 1, 2006 - Mar 31, 2008
    Gender differences in liver IL-6R expression
    Role: Principal Investigator

    R03OH009662     (GALLUCCI, RANDLE MICHAEL)Jul 1, 2009 - Jun 30, 2011
    The role of IL-6 in jet fuel irritant dermatitis
    Role: Principal Investigator

    R03ES020546     (GALLUCCI, RANDLE MICHAEL)Feb 7, 2012 - Jan 31, 2014
    Dermatological effects of gulf oil
    Role: Principal Investigator

    R01OH010241     (GALLUCCI, RANDLE MICHAEL)Sep 1, 2013 - Aug 31, 2018
    The Role of IL-6 Receptor in Irritant Dermatitis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dib P, Zhang Y, Ihnat MA, Gallucci RM, Standifer KM. TNF-Alpha as an Initiator of Allodynia and Anxiety-Like Behaviors in a Preclinical Model of PTSD and Comorbid Pain. Front Psychiatry. 2021; 12:721999. PMID: 34512420.
    2. Luckett-Chastain LR, King CJ, McShan WM, Gipson JR, Gillaspy AF, Gallucci RM. Loss of Interleukin-6 Influences Transcriptional Immune Signatures and Alters Bacterial Colonization in the Skin. Front Microbiol. 2021; 12:658980. PMID: 34295313.
    3. Kemp JM, Luckett-Chastain LR, Calhoun KN, Frempah B, Schartz TR, Harty LE, Kemp PM, Gallucci RM. Evaluation of skin irritation following weathered crude oil exposure in two mouse strains. Toxicol Ind Health. 2020 Oct; 36(10):788-799. PMID: 32807044.
      Citations:    Fields:    Translation:HumansAnimalsPHPublic Health
    4. Frempah B, Luckett-Chastain LR, Gallucci RM. IL-6 Negatively Regulates IL-22Ra Expression on Epidermal Keratinocytes: Implications for Irritant Contact Dermatitis. J Immunol Res. 2019; 2019:6276254. PMID: 31781680.
      Citations: 1     Fields:    Translation:AnimalsCells
    5. Frempah B, Luckett-Chastain LR, Gallucci RM. IL6Ra function in myeloid cells modulates the inflammatory response during irritant contact dermatitis. Exp Dermatol. 2019 08; 28(8):948-955. PMID: 31165501.
      Citations: 1     Fields:    Translation:AnimalsCells
    6. Frempah B, Luckett-Chastain LR, Calhoun KN, Gallucci RM. Keratinocyte-specific deletion of the IL-6R? exacerbates the inflammatory response during irritant contact dermatitis. Toxicology. 2019 07 01; 423:123-131. PMID: 31158415.
      Citations: 3     Fields:    Translation:AnimalsCells
    7. Lee EG, Luckett-Chastain LR, Calhoun KN, Frempah B, Bastian A, Gallucci RM. Interleukin 6 Function in the Skin and Isolated Keratinocytes Is Modulated by Hyperglycemia. J Immunol Res. 2019; 2019:5087847. PMID: 31073533.
      Citations: 8     Fields:    Translation:AnimalsCells
    8. Calhoun KN, Luckett-Chastain LR, Frempah B, Gallucci RM. Associations Between Immune Phenotype and Inflammation in Murine Models of Irritant Contact Dermatitis. Toxicol Sci. 2019 03 01; 168(1):179-189. PMID: 30517752.
      Citations: 3     Fields:    Translation:AnimalsCells
    9. Ojeda AS, Ford SD, Gallucci RM, Ihnat MA, Philp RP. Geochemical characterization and renal cell toxicity of water-soluble extracts from U.S. Gulf Coast lignite. Environ Geochem Health. 2019 Apr; 41(2):1037-1053. PMID: 30276587.
      Citations:    Fields:    Translation:HumansCells
    10. Luckett-Chastain LR, Gipson JR, Gillaspy AF, Gallucci RM. Transcriptional profiling of irritant contact dermatitis (ICD) in a mouse model identifies specific patterns of gene expression and immune-regulation. Toxicology. 2018 12 01; 410:1-9. PMID: 30171875.
      Citations: 3     Fields:    Translation:AnimalsCells
    11. Gallucci RM. Transforming growth factor-ß and psoriasis: a new link. Br J Dermatol. 2017 12; 177(6):1480-1481. PMID: 29313920.
      Citations:    Fields:    Translation:HumansCells
    12. Luckett-Chastain LR, Cottrell ML, Kawar BM, Ihnat MA, Gallucci RM. Interleukin (IL)-6 modulates transforming growth factor-ß receptor I and II (TGF-ßRI and II) function in epidermal keratinocytes. Exp Dermatol. 2017 08; 26(8):697-704. PMID: 27892604.
      Citations: 4     Fields:    Translation:AnimalsCells
    13. Lee EG, Mickle-Kawar BM, Gallucci RM. IL-6 deficiency exacerbates skin inflammation in a murine model of irritant dermatitis. J Immunotoxicol. 2013 Apr-Jun; 10(2):192-200. PMID: 22966985.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    14. Lee EG, Mickle-Kawar BM, Reinke LA, Gallucci RM. Estrogen suppresses heptatic I?B expression during short-term alcohol exposure. Inflamm Res. 2012 Oct; 61(10):1053-61. PMID: 22669179.
      Citations: 5     Fields:    Translation:Animals
    15. Luckett-Chastain LR, Ihnat MA, Mickle-Kawar BM, Gallucci RM. SOCS3 modulates interleukin-6R signaling preference in dermal fibroblasts. J Interferon Cytokine Res. 2012 May; 32(5):207-15. PMID: 22313262.
      Citations: 3     Fields:    Translation:AnimalsCells
    16. Van Amburgh J, Surratt CK, Green JS, Gallucci RM, Colbert J, Zatopek SL, Blouin RA. Succession planning in US pharmacy schools. Am J Pharm Educ. 2010 Jun 15; 74(5). PMID: 20798799.
      Citations: 3     Fields:    Translation:Humans
    17. Luckett-Chastain LR, Gallucci RM. Interleukin (IL)-6 modulates transforming growth factor-beta expression in skin and dermal fibroblasts from IL-6-deficient mice. Br J Dermatol. 2009 Aug; 161(2):237-48. PMID: 19438433.
      Citations: 23     Fields:    Translation:AnimalsCells
    18. Larabee JL, Hocker JR, Cheung JY, Gallucci RM, Hanas JS. Serum Profiling of Rat Dermal Exposure to JP-8 Fuel Reveals an Acute-Phase Response. Toxicol Mech Methods. 2008; 18(1):41-51. PMID: 20020890.
      Citations: 2     Fields:    
    19. Saban MR, Simpson C, Davis C, Wallis G, Knowlton N, Frank MB, Centola M, Gallucci RM, Saban R. Discriminators of mouse bladder response to intravesical Bacillus Calmette-Guerin (BCG). BMC Immunol. 2007 May 16; 8:6. PMID: 17506885.
      Citations: 17     Fields:    Translation:AnimalsCells
    20. Luckett LR, Gallucci RM. Interleukin-6 (IL-6) modulates migration and matrix metalloproteinase function in dermal fibroblasts from IL-6KO mice. Br J Dermatol. 2007 Jun; 156(6):1163-71. PMID: 17441960.
      Citations: 26     Fields:    Translation:AnimalsCells
    21. Gallucci RM, Lee EG, Tomasek JJ. IL-6 modulates alpha-smooth muscle actin expression in dermal fibroblasts from IL-6-deficient mice. J Invest Dermatol. 2006 Mar; 126(3):561-8. PMID: 16397521.
      Citations: 42     Fields:    Translation:AnimalsCells
    22. Larabee JL, Hocker JR, Lerner MR, Lightfoot SA, Cheung JY, Brackett DJ, Gallucci RM, Hanas JS. Stress induced in heart and other tissues by rat dermal exposure to JP-8 fuel. Cell Biol Toxicol. 2005 Sep-Nov; 21(5-6):233-46. PMID: 16323059.
      Citations: 1     Fields:    Translation:AnimalsCells
    23. Gallucci RM, O'Dell SK, Rabe D, Fechter LD. JP-8 jet fuel exposure induces inflammatory cytokines in rat skin. Int Immunopharmacol. 2004 Sep; 4(9):1159-69. PMID: 15251112.
      Citations: 1     Fields:    Translation:AnimalsCells
    24. Gallucci RM, Sloan DK, O'Dell SJ, Reinke LA. Differential expression of liver interleukin-6 receptor-alpha in female versus male ethanol-consuming rats. Alcohol Clin Exp Res. 2004 Mar; 28(3):365-73. PMID: 15084893.
      Citations: 8     Fields:    Translation:Animals
    25. Gallucci RM, Sloan DK, Heck JM, Murray AR, O'Dell SJ. Interleukin 6 indirectly induces keratinocyte migration. J Invest Dermatol. 2004 Mar; 122(3):764-72. PMID: 15086564.
      Citations: 51     Fields:    Translation:AnimalsCells
    26. Simeonova PP, Gallucci RM, Hulderman T, Wilson R, Kommineni C, Rao M, Luster MI. The role of tumor necrosis factor-alpha in liver toxicity, inflammation, and fibrosis induced by carbon tetrachloride. Toxicol Appl Pharmacol. 2001 Dec 01; 177(2):112-20. PMID: 11740910.
      Citations: 58     Fields:    Translation:Animals
    27. Sugawara T, Gallucci RM, Simeonova PP, Luster MI. Regulation and role of interleukin 6 in wounded human epithelial keratinocytes. Cytokine. 2001 Sep 21; 15(6):328-36. PMID: 11594800.
      Citations: 25     Fields:    Translation:HumansCells
    28. Gallucci RM, Sugawara T, Yucesoy B, Berryann K, Simeonova PP, Matheson JM, Luster MI. Interleukin-6 treatment augments cutaneous wound healing in immunosuppressed mice. J Interferon Cytokine Res. 2001 Aug; 21(8):603-9. PMID: 11559438.
      Citations: 31     Fields:    Translation:Animals
    29. Gallucci RM, Simeonova PP, Matheson JM, Kommineni C, Guriel JL, Sugawara T, Luster MI. Impaired cutaneous wound healing in interleukin-6-deficient and immunosuppressed mice. FASEB J. 2000 Dec; 14(15):2525-31. PMID: 11099471.
      Citations: 118     Fields:    Translation:Animals
    30. Spitzer JH, Núñez NP, Meadows SA, Gallucci RM, Blank SE, Meadows GG. The modulation of B16BL6 melanoma metastasis is not directly mediated by cytolytic activity of natural killer cells in alcohol-consuming mice. Alcohol Clin Exp Res. 2000 Jun; 24(6):837-44. PMID: 10888072.
      Citations: 4     Fields:    Translation:AnimalsCells
    31. Gallucci RM, Simeonova PP, Toriumi W, Luster MI. TNF-alpha regulates transforming growth factor-alpha expression in regenerating murine liver and isolated hepatocytes. J Immunol. 2000 Jan 15; 164(2):872-8. PMID: 10623834.
      Citations: 20     Fields:    Translation:AnimalsCells
    32. Luster MI, Simeonova PP, Gallucci RM, Bruccoleri A, Blazka ME, Yucesoy B, Matheson JM. The role of tumor necrosis factor alpha in chemical-induced hepatotoxicity. Ann N Y Acad Sci. 2000; 919:214-20. PMID: 11083111.
      Citations: 2     Fields:    Translation:AnimalsCells
    33. Yin M, Wheeler MD, Kono H, Bradford BU, Gallucci RM, Luster MI, Thurman RG. Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice. Gastroenterology. 1999 Oct; 117(4):942-52. PMID: 10500078.
      Citations: 204     Fields:    Translation:AnimalsCells
    34. Dong W, Simeonova PP, Gallucci R, Matheson J, Flood L, Wang S, Hubbs A, Luster MI. Toxic metals stimulate inflammatory cytokines in hepatocytes through oxidative stress mechanisms. Toxicol Appl Pharmacol. 1998 Aug; 151(2):359-66. PMID: 9707512.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    35. Dong W, Simeonova PP, Gallucci R, Matheson J, Fannin R, Montuschi P, Flood L, Luster MI. Cytokine expression in hepatocytes: role of oxidant stress. J Interferon Cytokine Res. 1998 Aug; 18(8):629-38. PMID: 9726445.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    36. Iimuro Y, Gallucci RM, Luster MI, Kono H, Thurman RG. Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology. 1997 Dec; 26(6):1530-7. PMID: 9397994.
      Citations: 118     Fields:    Translation:Animals
    37. Blank SE, Jones TB, Lee EG, Brahler CJ, Gallucci RM, Fox ML, Meadows GG. Modulation of NK cell cytolytic activity by macrophages in chronically exercise-stressed mice. J Appl Physiol (1985). 1997 Sep; 83(3):845-50. PMID: 9292472.
      Citations: 1     Fields:    Translation:AnimalsCells
    38. Bruccoleri A, Gallucci R, Germolec DR, Blackshear P, Simeonova P, Thurman RG, Luster MI. Induction of early-immediate genes by tumor necrosis factor alpha contribute to liver repair following chemical-induced hepatotoxicity. Hepatology. 1997 Jan; 25(1):133-41. PMID: 8985279.
      Citations: 28     Fields:    Translation:Animals
    39. Gallucci RM, Meadows GG. Ethanol consumption suppresses the IL2-induced proliferation of NK cells. Toxicol Appl Pharmacol. 1996 May; 138(1):90-7. PMID: 8658518.
      Citations: 6     Fields:    Translation:AnimalsCells
    40. Gallucci RM, Meadows GG. Ethanol consumption reduces the cytolytic activity of lymphokine-activated killer cells. Alcohol Clin Exp Res. 1995 Apr; 19(2):402-9. PMID: 7625574.
      Citations: 3     Fields:    Translation:AnimalsCells
    41. Gallucci RM, Pfister LJ, Meadows GG. Effects of ethanol consumption on enriched natural killer cells from C57BL/6 mice. Alcohol Clin Exp Res. 1994 Jun; 18(3):625-31. PMID: 7943666.
      Citations: 8     Fields:    Translation:AnimalsCells
    42. Blank SE, Johansson JO, Pfister LJ, Gallucci RM, Lee EG, Meadows GG. Mechanistic differences in NK cell cytolytic activity in treadmill-trained and chronic ethanol-consuming mice. J Appl Physiol (1985). 1994 May; 76(5):2031-6. PMID: 8063666.
      Citations: 4     Fields:    Translation:AnimalsCells
    43. Blank SE, Gallucci RM, Wang JH, Meadows GG. Factors involved in modulation of NK cell activity by ethanol consumption. Alcohol Alcohol Suppl. 1994; 2:439-45. PMID: 8974366.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    44. Blank SE, Pfister LJ, Gallucci RM, Meadows GG. Ethanol-induced changes in peripheral blood and splenic natural killer cells. Alcohol Clin Exp Res. 1993 Jun; 17(3):561-5. PMID: 8333585.
      Citations: 9     Fields:    Translation:AnimalsCells
    45. Meadows GG, Elstad CA, Blank SE, Gallucci RM, Pfister LJ. Alcohol consumption suppresses metastasis of B16-BL6 melanoma in mice. Clin Exp Metastasis. 1993 Mar; 11(2):191-9. PMID: 8444011.
      Citations: 8     Fields:    Translation:AnimalsCells
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