"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
| Descriptor ID |
D035683
|
| MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
|
| Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
|
Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 2 | 0 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 3 | 0 | 3 |
| 2010 | 2 | 0 | 2 |
| 2011 | 4 | 0 | 4 |
| 2012 | 4 | 1 | 5 |
| 2013 | 10 | 3 | 13 |
| 2014 | 7 | 4 | 11 |
| 2015 | 12 | 4 | 16 |
| 2016 | 16 | 0 | 16 |
| 2017 | 7 | 2 | 9 |
| 2018 | 6 | 0 | 6 |
| 2019 | 9 | 0 | 9 |
| 2020 | 6 | 2 | 8 |
| 2021 | 6 | 2 | 8 |
| 2022 | 13 | 1 | 14 |
| 2023 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "MicroRNAs" by people in Profiles.
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miR-18a and miR-106a Signatures in Plasma Small EVs Are Promising Biomarkers for Early Detection of Pancreatic Ductal Adenocarcinoma. Int J Mol Sci. 2023 Apr 13; 24(8).
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MiR-205-5P AS POTENTIAL BIOMARKER AND THERAPEUTIC TARGET IN HEAD AND NECK SQUAMOUS CELL CARCINOMA. Exp Oncol. 2022 12; 44(4):337-338.
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Circulating microRNA responses to acute whole-body vibration and resistance exercise in postmenopausal women. Front Endocrinol (Lausanne). 2022; 13:1038371.
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miR-130b/301b Is a Negative Regulator of Beige Adipogenesis and Energy Metabolism In Vitro and In Vivo. Diabetes. 2022 Nov 01; 71(11):2360-2371.
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MICRORNA-31 AS A POTENTIAL THERAPEUTIC BIOMARKER FOR?ORAL SQUAMOUS CELL CARCINOMA: CURRENT EVIDENCE AND FUTURE PROSPECTS. Exp Oncol. 2022 11; 44(3):263-264.
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Target-Triggered Formation of Artificial Enzymes on Filamentous Phage for Ultrasensitive Direct Detection of Circulating miRNA Biomarkers in Clinical Samples. Angew Chem Int Ed Engl. 2022 11 07; 61(45):e202210121.
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Pan-genomic, transcriptomic, and miRNA analyses to decipher genetic diversity and anthocyanin pathway genes among the traditional rice landraces. Genomics. 2022 09; 114(5):110436.
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Transplantation of bone marrow cells from miR150 knockout mice improves senescence-associated humoral immune dysfunction and arterial stiffness. Metabolism. 2022 09; 134:155249.
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Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature. Ann Rheum Dis. 2022 10; 81(10):1428-1437.
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Integrated analysis of ascites and plasma extracellular vesicles identifies a miRNA-based diagnostic signature in ovarian cancer. Cancer Lett. 2022 08 28; 542:215735.