"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
Descriptor ID |
D035683
|
MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
|
Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
|
Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2007 | 2 | 0 | 2 |
2008 | 2 | 0 | 2 |
2009 | 3 | 0 | 3 |
2010 | 3 | 0 | 3 |
2011 | 4 | 0 | 4 |
2012 | 4 | 2 | 6 |
2013 | 10 | 2 | 12 |
2014 | 3 | 4 | 7 |
2015 | 12 | 5 | 17 |
2016 | 16 | 0 | 16 |
2017 | 8 | 2 | 10 |
2018 | 7 | 0 | 7 |
2019 | 9 | 0 | 9 |
2020 | 6 | 3 | 9 |
2021 | 5 | 2 | 7 |
2022 | 8 | 1 | 9 |
To return to the timeline,
click here.
Below are the most recent publications written about "MicroRNAs" by people in Profiles.
-
Pan-genomic, transcriptomic, and miRNA analyses to decipher genetic diversity and anthocyanin pathway genes among the traditional rice landraces. Genomics. 2022 09; 114(5):110436.
-
Transplantation of bone marrow cells from miR150 knockout mice improves senescence-associated humoral immune dysfunction and arterial stiffness. Metabolism. 2022 09; 134:155249.
-
Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature. Ann Rheum Dis. 2022 10; 81(10):1428-1437.
-
X-linked genes exhibit miR6891-5p-regulated skewing in Sjögren's syndrome. J Mol Med (Berl). 2022 Sep; 100(9):1253-1265.
-
Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-ß Signaling Axis in Pancreatic Cancer. Gastroenterology. 2022 06; 162(7):2004-2017.e2.
-
Gestational Diabetes Mellitus Is Associated with Altered Abundance of Exosomal MicroRNAs in Human Milk. Clin Ther. 2022 02; 44(2):172-185.e1.
-
Bioactive compounds in mothers milk affecting offspring outcomes: A narrative review. Pediatr Obes. 2022 07; 17(7):e12892.
-
Neuronally-enriched exosomal microRNA-27b mediates acute effects of ibuprofen on reward-related brain activity in healthy adults: a randomized, placebo-controlled, double-blind trial. Sci Rep. 2022 01 17; 12(1):861.
-
Differential expression of microRNA between triple negative breast cancer patients of African American and European American descent. Biotech Histochem. 2022 Jan; 97(1):1-10.
-
An Update on the Molecular and Clinical Characteristics of Apocrine Carcinoma of the Breast. Clin Breast Cancer. 2022 06; 22(4):e576-e585.