Myeloid Differentiation Factor 88
"Myeloid Differentiation Factor 88" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.
| Descriptor ID |
D053594
|
| MeSH Number(s) |
D12.644.360.024.311 D12.776.157.057.074 D12.776.476.024.390
|
| Concept/Terms |
Myeloid Differentiation Factor 88- Myeloid Differentiation Factor 88
- Toll-Like Receptor Signal Adaptor Protein MyD88
- Toll Like Receptor Signal Adaptor Protein MyD88
- MyD88 Protein
- TLR Signal Adaptor Protein MyD88
|
Below are MeSH descriptors whose meaning is more general than "Myeloid Differentiation Factor 88".
Below are MeSH descriptors whose meaning is more specific than "Myeloid Differentiation Factor 88".
This graph shows the total number of publications written about "Myeloid Differentiation Factor 88" by people in this website by year, and whether "Myeloid Differentiation Factor 88" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2014 | 3 | 1 | 4 |
| 2015 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myeloid Differentiation Factor 88" by people in Profiles.
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Effect of epithelial-specific MyD88 signaling pathway on airway inflammatory response to organic dust exposure. J Immunotoxicol. 2023 12; 20(1):2148782.
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Hyperacute Monocyte Gene Response Patterns Are Associated With Lower Extremity Vein Bypass Graft Failure. Circ Genom Precis Med. 2018 03; 11(3):e001970.
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Roles of TLR/MyD88/MAPK/NF-?B Signaling Pathways in the Regulation of Phagocytosis and Proinflammatory Cytokine Expression in Response to E. faecalis Infection. PLoS One. 2015; 10(8):e0136947.
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Unexpected Roles for Toll-Like Receptor 4 and TRIF in Intraocular Infection with Gram-Positive Bacteria. Infect Immun. 2015 Oct; 83(10):3926-36.
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TLR-4 signalling pathway: MyD88 independent pathway up-regulation in chicken breeds upon LPS treatment. Vet Res Commun. 2015 Mar; 39(1):73-8.
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A TIR domain protein from E. faecalis attenuates MyD88-mediated signaling and NF-?B activation. PLoS One. 2014; 9(11):e112010.
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Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice. J Neuroinflammation. 2014 Aug 13; 11:143.
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Phosphoproteome profiling of the macrophage response to different toll-like receptor ligands identifies differences in global phosphorylation dynamics. J Proteome Res. 2014 Nov 07; 13(11):5185-97.
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Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity. Cell Metab. 2014 May 06; 19(5):821-35.
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Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells. Ann Rheum Dis. 2010 Jun; 69(6):1195-9.