"Interleukin-23" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-23 is comprised of a unique 19 kDa subunit and 40 kDa subunit that is shared with INTERLEUKIN-12. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells
Descriptor ID |
D053759
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MeSH Number(s) |
D12.644.276.374.465.759 D12.776.467.374.465.759 D23.529.374.465.550
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interleukin-23".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-23".
This graph shows the total number of publications written about "Interleukin-23" by people in this website by year, and whether "Interleukin-23" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2012 | 1 | 2 | 3 |
2013 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-23" by people in Profiles.
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Agasing A, Quinn JL, Kumar G, Axtell RC. Interferon-ß Intensifies Interleukin-23-Driven Pathogenicity of T Helper Cells in Neuroinflammatory Disease. Cells. 2021 08 20; 10(8).
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Seshadri S, Allan DSJ, Carlyle JR, Zenewicz LA. Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling. PLoS Pathog. 2017 Oct; 13(10):e1006690.
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Davidson MG, Alonso MN, Yuan R, Axtell RC, Kenkel JA, Suhoski MM, González JC, Steinman L, Engleman EG. Th17 cells induce Th1-polarizing monocyte-derived dendritic cells. J Immunol. 2013 Aug 01; 191(3):1175-87.
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Yano J, Kolls JK, Happel KI, Wormley F, Wozniak KL, Fidel PL. The acute neutrophil response mediated by S100 alarmins during vaginal Candida infections is independent of the Th17-pathway. PLoS One. 2012; 7(9):e46311.
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Wight RD, Tull CA, Deel MW, Stroope BL, Eubanks AG, Chavis JA, Drew PD, Hensley LL. Resveratrol effects on astrocyte function: relevance to neurodegenerative diseases. Biochem Biophys Res Commun. 2012 Sep 14; 426(1):112-5.
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Kinnebrew MA, Buffie CG, Diehl GE, Zenewicz LA, Leiner I, Hohl TM, Flavell RA, Littman DR, Pamer EG. Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense. Immunity. 2012 Feb 24; 36(2):276-87.