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Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

"Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A transcriptional co-activator for NUCLEAR RECEPTORS. It is characterized by an N-terminal LxxLL sequence, a region that interacts with PPAR GAMMA, and a C-terminal RNA RECOGNITION MOTIF. It increases expression of MITOCHONDRIAL UNCOUPLING PROTEIN to regulate genes involved in metabolic reprogramming in response to dietary restriction and the integration of CIRCADIAN RHYTHMS with ENERGY METABOLISM.


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This graph shows the total number of publications written about "Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha" by people in this website by year, and whether "Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha" was a major or minor topic of these publications.
Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 2017 and 2020
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