Shc Signaling Adaptor Proteins
"Shc Signaling Adaptor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of signaling adaptor proteins that contain SRC HOMOLOGY DOMAINS. Many members of this family are involved in transmitting signals from CELL SURFACE RECEPTORS to MITOGEN-ACTIVATED PROTEIN KINASES.
| Descriptor ID |
D055765
|
| MeSH Number(s) |
D12.644.360.024.330 D12.776.157.057.162 D12.776.476.024.424
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Shc Signaling Adaptor Proteins".
Below are MeSH descriptors whose meaning is more specific than "Shc Signaling Adaptor Proteins".
This graph shows the total number of publications written about "Shc Signaling Adaptor Proteins" by people in this website by year, and whether "Shc Signaling Adaptor Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Shc Signaling Adaptor Proteins" by people in Profiles.
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p66Shc in Cardiovascular Pathology. Cells. 2022 06 06; 11(11).
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Conformation-Dependent Human p52Shc Phosphorylation by Human c-Src. Biochemistry. 2015 Jun 09; 54(22):3469-82.
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SHetA2 interference with mortalin binding to p66shc and p53 identified using drug-conjugated magnetic microspheres. Invest New Drugs. 2014 Jun; 32(3):412-23.
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A positive feedback loop of ER-a36/EGFR promotes malignant growth of ER-negative breast cancer cells. Oncogene. 2011 Feb 17; 30(7):770-80.
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Protein interactions of Src homology 2 (SH2) domain-containing inositol phosphatase (SHIP): association with Shc displaces SHIP from FcgammaRIIb in B cells. J Immunol. 1999 Feb 01; 162(3):1408-14.
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Modulation of insulin-like growth factor actions in L6A1 myoblasts by insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5: a dual role for IGFBP-5. J Cell Physiol. 1998 Oct; 177(1):47-57.
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Evidence for a direct interaction between insulin receptor substrate-1 and Shc. J Biol Chem. 1997 Jul 04; 272(27):17166-70.
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Negative signaling in B cells causes reduced Ras activity by reducing Shc-Grb2 interactions. J Immunol. 1997 Feb 01; 158(3):1125-32.