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TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1.
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TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1.
TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1. Sci Signal. 2010 May 18; 3(122):ra38.
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subject areas
Adaptor Proteins, Signal Transducing
Adaptor Proteins, Signal Transducing
Animals
Animals
Cell Division
Cell Division
Cell Line
Cell Line
Enzyme Activation
Enzyme Activation
Inositol Polyphosphate 5-Phosphatases
Inositol Polyphosphate 5-Phosphatases
Membrane Glycoproteins
Membrane Glycoproteins
Mice
Mice
Mice, Inbred C57BL
Mice, Inbred C57BL
Osteoclasts
Osteoclasts
Phosphatidylinositol 3-Kinases
Phosphatidylinositol 3-Kinases
Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
Phosphoric Monoester Hydrolases
Phosphoric Monoester Hydrolases
Phosphorylation
Phosphorylation
Receptors, Immunologic
Receptors, Immunologic
Signal Transduction
Signal Transduction
src Homology Domains
src Homology Domains
authors with profiles
K Mark Coggeshall
Mary Beth Humphrey