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Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
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Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression. PLoS Genet. 2013; 9(10):e1003870.
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PubMed
subject areas
Alleles
Alleles
ets-Domain Protein Elk-1
ets-Domain Protein Elk-1
Gene Expression Regulation
Gene Expression Regulation
Genetic Predisposition to Disease
Genetic Predisposition to Disease
Genome-Wide Association Study
Genome-Wide Association Study
Genotype
Genotype
Haplotypes
Haplotypes
Humans
Humans
Interleukin-10
Interleukin-10
Introns
Introns
Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
Polymorphism, Single Nucleotide
Polymorphism, Single Nucleotide
Protein Binding
Protein Binding
Up-Regulation
Up-Regulation
authors with profiles
Patrick Gaffney
Joan Merrill
Judith A James