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Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.
Principal Investigator
Monckeberg Medial Calcific Sclerosis
Molecular and cellular mechanisms of lymphatic vascular maturation.
CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity.
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CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity.
CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity. J Clin Invest. 2016 06 01; 126(6):2254-66.
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PubMed
subject areas
Animals
DNA Helicases
Enzyme Activation
Female
Fibrinolysin
Glycoproteins
Hemostasis
Liver
Lymphangiogenesis
Lymphatic Vessels
Membrane Transport Proteins
Mice
Mice, Knockout
Neovascularization, Physiologic
Pregnancy
Receptors, Urokinase Plasminogen Activator
Up-Regulation
authors with profiles
Courtney T Griffin