High-Temperature Requirement A Serine Peptidase 1
"High-Temperature Requirement A Serine Peptidase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted serine protease that contains a Kazal domain-like region and a C-terminal PDZ domain. It has a broad range of targets that include EXTRACELLULAR MATRIX PROTEINS; PROTEOGLYCANS; and INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS. Mutations in the HTRA1 gene are associated with AGE-RELATED MACULAR DEGENERATION 7 and Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL).
| Descriptor ID |
D000074289
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| MeSH Number(s) |
D08.811.277.656.300.760.420 D08.811.277.656.959.350.420
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "High-Temperature Requirement A Serine Peptidase 1".
Below are MeSH descriptors whose meaning is more specific than "High-Temperature Requirement A Serine Peptidase 1".
This graph shows the total number of publications written about "High-Temperature Requirement A Serine Peptidase 1" by people in this website by year, and whether "High-Temperature Requirement A Serine Peptidase 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "High-Temperature Requirement A Serine Peptidase 1" by people in Profiles.
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Agnihotri S, Jalali S, Wilson MR, Danesh A, Li M, Klironomos G, Krieger JR, Mansouri A, Khan O, Mamatjan Y, Landon-Brace N, Tung T, Dowar M, Li T, Bruce JP, Burrell KE, Tonge PD, Alamsahebpour A, Krischek B, Agarwalla PK, Bi WL, Dunn IF, Beroukhim R, Fehlings MG, Bril V, Pagnotta SM, Iavarone A, Pugh TJ, Aldape KD, Zadeh G. The genomic landscape of schwannoma. Nat Genet. 2016 11; 48(11):1339-1348.