The murine double-stranded RNA-dependent protein kinase PKR and the murine 2',5'-oligoadenylate synthetase-dependent RNase L are required for IFN-beta-mediated resistance against herpes simplex virus type 1 in primary trigeminal ganglion culture.
The murine double-stranded RNA-dependent protein kinase PKR and the murine 2',5'-oligoadenylate synthetase-dependent RNase L are required for IFN-beta-mediated resistance against herpes simplex virus type 1 in primary trigeminal ganglion culture. Virology. 2003 Aug 15; 313(1):126-35.
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Adenoviridae
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Adenoviridae
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Animals
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Animals
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Cells, Cultured
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Cells, Cultured
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eIF-2 Kinase
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eIF-2 Kinase
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Endoribonucleases
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Endoribonucleases
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Female
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Female
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Genetic Therapy
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Genetic Therapy
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Genetic Vectors
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Genetic Vectors
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Herpesvirus 1, Human
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Herpesvirus 1, Human
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Interferon-beta
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Interferon-beta
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Mice
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Mice
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Mice, Inbred C57BL
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Mice, Inbred C57BL
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Mice, Inbred ICR
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Mice, Inbred ICR
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Mice, Knockout
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Mice, Knockout
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Neurons
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Neurons
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Transduction, Genetic
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Transduction, Genetic
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Trigeminal Ganglion
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Trigeminal Ganglion