"Patched-1 Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A patched receptor for several HEDGEHOG PROTEINS that associates with the SMOOTHENED RECEPTOR to modulate hedgehog signaling. It is also a TUMOR SUPPRESSOR PROTEIN; mutations in the patched-1 gene are associated with BASAL CELL NEVUS SYNDROME; SQUAMOUS CELL CARCNIOMA of the ESOPHAGUS; trichoepitheliomas, and CARCINOMA, TRANSITIONAL CELL of the URINARY BLADDER.
- Patched-1 Receptor
- Patched 1 Receptor
- Receptor, Patched-1
- PTCH1 Protein
- Patched Homolog-1
- Patched Homolog 1
- Patched-1 Protein
- Patched 1 Protein
- Patched Receptor-1
- Patched Receptor 1
- Receptor-1, Patched
Below are MeSH descriptors whose meaning is more general than "Patched-1 Receptor".
Below are MeSH descriptors whose meaning is more specific than "Patched-1 Receptor".
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Below are the most recent publications written about "Patched-1 Receptor" by people in Profiles.
Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome. Nat Cell Biol. 2017 Oct; 19(10):1178-1188.
The hedgehog-patched signaling pathway and function in the mammalian ovary: a novel role for hedgehog proteins in stimulating proliferation and steroidogenesis of theca cells. Reproduction. 2009 Aug; 138(2):329-39.
Expression of patched, prdm1 and engrailed in the lamprey somite reveals conserved responses to Hedgehog signaling. Evol Dev. 2009 Jan-Feb; 11(1):27-40.
Activation of the hedgehog pathway in advanced prostate cancer. Mol Cancer. 2004 Oct 13; 3:29.