"Patched Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS.
| Descriptor ID |
D000072079
|
| MeSH Number(s) |
D12.776.543.750.058 D12.776.624.776.633
|
| Concept/Terms |
Patched Receptors- Patched Receptors
- Receptors, Patched
- Patched Sonic Hedgehog Receptors
- Patched Receptor
- Receptor, Patched
- Patched Protein
|
Below are MeSH descriptors whose meaning is more general than "Patched Receptors".
Below are MeSH descriptors whose meaning is more specific than "Patched Receptors".
This graph shows the total number of publications written about "Patched Receptors" by people in this website by year, and whether "Patched Receptors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Patched Receptors" by people in Profiles.
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The hedgehog system in ovarian follicles of cattle selected for twin ovulations and births: evidence of a link between the IGF and hedgehog systems. Biol Reprod. 2012 Oct; 87(4):79.
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The hedgehog-patched signaling pathway and function in the mammalian ovary: a novel role for hedgehog proteins in stimulating proliferation and steroidogenesis of theca cells. Reproduction. 2009 Aug; 138(2):329-39.
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Expression of patched, prdm1 and engrailed in the lamprey somite reveals conserved responses to Hedgehog signaling. Evol Dev. 2009 Jan-Feb; 11(1):27-40.
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Activation of the hedgehog pathway in advanced prostate cancer. Mol Cancer. 2004 Oct 13; 3:29.