"Patched-1 Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A patched receptor for several HEDGEHOG PROTEINS that associates with the SMOOTHENED RECEPTOR to modulate hedgehog signaling. It is also a TUMOR SUPPRESSOR PROTEIN; mutations in the patched-1 gene are associated with BASAL CELL NEVUS SYNDROME; SQUAMOUS CELL CARCNIOMA of the ESOPHAGUS; trichoepitheliomas, and CARCINOMA, TRANSITIONAL CELL of the URINARY BLADDER.
| Descriptor ID |
D000072081
|
| MeSH Number(s) |
D12.776.543.750.058.500 D12.776.624.776.633.500
|
| Concept/Terms |
Patched-1 Receptor- Patched-1 Receptor
- Patched 1 Receptor
- Receptor, Patched-1
- PTCH1 Protein
- Patched Homolog-1
- Patched Homolog 1
- Patched-1 Protein
- Patched 1 Protein
- Patched Receptor-1
- Patched Receptor 1
- Receptor-1, Patched
|
Below are MeSH descriptors whose meaning is more general than "Patched-1 Receptor".
Below are MeSH descriptors whose meaning is more specific than "Patched-1 Receptor".
This graph shows the total number of publications written about "Patched-1 Receptor" by people in this website by year, and whether "Patched-1 Receptor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Patched-1 Receptor" by people in Profiles.
-
Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome. Nat Cell Biol. 2017 Oct; 19(10):1178-1188.
-
The hedgehog-patched signaling pathway and function in the mammalian ovary: a novel role for hedgehog proteins in stimulating proliferation and steroidogenesis of theca cells. Reproduction. 2009 Aug; 138(2):329-39.
-
Expression of patched, prdm1 and engrailed in the lamprey somite reveals conserved responses to Hedgehog signaling. Evol Dev. 2009 Jan-Feb; 11(1):27-40.
-
Activation of the hedgehog pathway in advanced prostate cancer. Mol Cancer. 2004 Oct 13; 3:29.