"Receptors, Notch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the CELL NUCLEUS, where they act as transcription factors.
Descriptor ID |
D051880
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MeSH Number(s) |
D12.776.543.750.725 D12.776.930.770
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptors, Notch".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Notch".
This graph shows the total number of publications written about "Receptors, Notch" by people in this website by year, and whether "Receptors, Notch" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 2 | 3 |
2011 | 0 | 2 | 2 |
2012 | 0 | 1 | 1 |
2013 | 2 | 1 | 3 |
2014 | 0 | 1 | 1 |
2015 | 3 | 0 | 3 |
2016 | 3 | 1 | 4 |
2017 | 0 | 1 | 1 |
2019 | 1 | 1 | 2 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Notch" by people in Profiles.
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The emerging role of NOTCH3 receptor signalling in human lung diseases. Expert Rev Mol Med. 2022 09 02; 24:e33.
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Optimized monoclonal antibody treatment against ELTD1 for GBM in a G55 xenograft mouse model. J Cell Mol Med. 2020 01; 24(2):1738-1749.
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ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis. Mol Cancer. 2019 11 07; 18(1):156.
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Adams-Oliver syndrome review of the literature: Refining the diagnostic phenotype. Am J Med Genet A. 2017 Mar; 173(3):790-800.
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Increased Wnt and Notch signaling: a clue to the renal disease in Schimke immuno-osseous dysplasia? Orphanet J Rare Dis. 2016 11 05; 11(1):149.
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JAG1-Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium. Stem Cell Rev Rep. 2016 Aug; 12(4):454-63.
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Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial. Clin Cancer Res. 2016 Oct 01; 22(19):4786-4796.
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Expanding the spectrum of ?-secretase gene mutation-associated phenotypes: two novel mutations segregating with familial hidradenitis suppurativa (acne inversa) and acne conglobata. Exp Dermatol. 2016 Apr; 25(4):314-6.
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DHA suppresses chronic apoptosis in the lung caused by perinatal inflammation. Am J Physiol Lung Cell Mol Physiol. 2015 Sep 01; 309(5):L441-8.
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Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update. Nat Rev Clin Oncol. 2015 Aug; 12(8):445-64.