"Receptors, Retinoic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins in the nucleus or cytoplasm that specifically bind RETINOIC ACID or RETINOL and trigger changes in the behavior of cells. Retinoic acid receptors, like steroid receptors, are ligand-activated transcription regulators. Several types have been recognized.
| Descriptor ID |
D018168
|
| MeSH Number(s) |
D12.776.826.701 D12.776.930.775
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Retinoic Acid".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Retinoic Acid".
This graph shows the total number of publications written about "Receptors, Retinoic Acid" by people in this website by year, and whether "Receptors, Retinoic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 3 | 0 | 3 |
| 1999 | 3 | 1 | 4 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 2 | 3 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Retinoic Acid" by people in Profiles.
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Identification of Apolipoprotein A-I as a Retinoic Acid-binding Protein in the Eye. J Biol Chem. 2016 09 02; 291(36):18991-9005.
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History of retinoic acid receptors. Subcell Biochem. 2014; 70:1-20.
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Modification of the zonal elution method for detection of transient protein-protein interactions involving ligand exchange. Anal Chem. 2012 May 15; 84(10):4608-12.
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Qualitative and quantitative promoter hypermethylation patterns of the P16, TSHR, RASSF1A and RARß2 genes in papillary thyroid carcinoma. Med Oncol. 2011 Dec; 28(4):1123-8.
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Transporter-to-trap conversion: a disulfide bond formation in cellular retinoic acid binding protein I mutant triggered by retinoic acid binding irreversibly locks the ligand inside the protein. Biochemistry. 2007 Nov 20; 46(46):13382-90.
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Flexible heteroarotinoids (Flex-Hets) exhibit improved therapeutic ratios as anti-cancer agents over retinoic acid receptor agonists. Invest New Drugs. 2005 Oct; 23(5):417-28.
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Crustacean retinoid-X receptor isoforms: distinctive DNA binding and receptor-receptor interaction with a cognate ecdysteroid receptor. Mol Cell Endocrinol. 2004 Apr 15; 218(1-2):21-38.
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Synthesis of flexible sulfur-containing heteroarotinoids that induce apoptosis and reactive oxygen species with discrimination between malignant and benign cells. J Med Chem. 2004 Feb 12; 47(4):999-1007.
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Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu. J Biol Chem. 2004 Apr 09; 279(15):14909-16.
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Visual cycle retinoid processing proteins are present in HEK293S cells. Vision Res. 2003 Dec; 43(28):3037-44.