Retinoic Acid Receptor alpha
"Retinoic Acid Receptor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear receptor protein which belongs to a family of transcription regulators of ligand-responsive regulatory proteins which include steroid hormone receptors. In addition to a C-terminal ligand-binding domain, these nuclear receptors contain a highly-conserved N-terminal zinc-finger domain that mediates binding ligand-responsive elements.
| Descriptor ID |
D000072482
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| MeSH Number(s) |
D12.776.826.701.250 D12.776.930.775.250
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinoic Acid Receptor alpha".
Below are MeSH descriptors whose meaning is more specific than "Retinoic Acid Receptor alpha".
This graph shows the total number of publications written about "Retinoic Acid Receptor alpha" by people in this website by year, and whether "Retinoic Acid Receptor alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
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Below are the most recent publications written about "Retinoic Acid Receptor alpha" by people in Profiles.
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Heteroarotinoids inhibit head and neck cancer cell lines in vitro and in vivo through both RAR and RXR retinoic acid receptors. J Med Chem. 1999 Oct 21; 42(21):4434-45.
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Retinoid signaling in immortalized and carcinoma-derived human uroepithelial cells. Mol Cell Endocrinol. 1999 Feb 25; 148(1-2):55-65.
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Biological assay for activity and molecular mechanism of retinoids in cervical tumor cells. Gynecol Oncol. 1997 Jul; 66(1):114-21.