X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms.
Sharma R, Deshmukh US, Zheng L, Fu SM, Ju ST. X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms. J Immunol. 2009 Sep 01; 183(5):3212-8.
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Animals
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Animals
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Female
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Female
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Forkhead Transcription Factors
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Forkhead Transcription Factors
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Genes, Dominant
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Genes, Dominant
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Genetic Predisposition to Disease
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Genetic Predisposition to Disease
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Genitalia, Male
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Genitalia, Male
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Immunity, Innate
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Immunity, Innate
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Inflammation Mediators
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Inflammation Mediators
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Male
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Male
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Mice
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Mice
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Mice, Inbred C57BL
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Mice, Inbred C57BL
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Mice, Knockout
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Mice, Knockout
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Mice, Transgenic
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Mice, Transgenic
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Mutation
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Mutation
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Organ Specificity
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Organ Specificity
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Submandibular Gland
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Submandibular Gland
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X Chromosome
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X Chromosome