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Identification of key residues determining isomerohydrolase activity of human RPE65.
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Identification of key residues determining isomerohydrolase activity of human RPE65.
Takahashi Y, Moiseyev G, Ma JX. Identification of key residues determining isomerohydrolase activity of human RPE65. J Biol Chem. 2014 Sep 26; 289(39):26743-26751.
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PubMed
subject areas
Amino Acid Substitution
Amino Acid Substitution
Animals
Animals
Cattle
Cattle
Cell Line
Cell Line
Chickens
Chickens
cis-trans-Isomerases
cis-trans-Isomerases
Genetic Diseases, Inborn
Genetic Diseases, Inborn
Genetic Therapy
Genetic Therapy
Humans
Humans
Mutagenesis, Site-Directed
Mutagenesis, Site-Directed
Mutation, Missense
Mutation, Missense
Retinal Degeneration
Retinal Degeneration
Species Specificity
Species Specificity
Structure-Activity Relationship
Structure-Activity Relationship
authors with profiles
Gennadiy Petrovich Moiseyev
Yusuke Takahashi