Single-chain HLA-A2 MHC trimers that incorporate an immundominant peptide elicit protective T cell immunity against lethal West Nile virus infection.
Kim S, Li L, McMurtrey CP, Hildebrand WH, Weidanz JA, Gillanders WE, Diamond MS, Hansen TH. Single-chain HLA-A2 MHC trimers that incorporate an immundominant peptide elicit protective T cell immunity against lethal West Nile virus infection. J Immunol. 2010 Apr 15; 184(8):4423-30.
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Animals
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Animals
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CD8-Positive T-Lymphocytes
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CD8-Positive T-Lymphocytes
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Cells, Cultured
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Cells, Cultured
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Cytotoxicity, Immunologic
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Cytotoxicity, Immunologic
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Disease Models, Animal
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Disease Models, Animal
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Epitopes, T-Lymphocyte
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Epitopes, T-Lymphocyte
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HLA-A2 Antigen
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HLA-A2 Antigen
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Humans
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Humans
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Immunodominant Epitopes
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Immunodominant Epitopes
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Mice
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Mice
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Mice, Transgenic
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Mice, Transgenic
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Protein Binding
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Protein Binding
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Survival Analysis
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Survival Analysis
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T-Lymphocytes, Helper-Inducer
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T-Lymphocytes, Helper-Inducer
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Vaccines, DNA
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Vaccines, DNA
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Vaccines, Subunit
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Vaccines, Subunit
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Viral Load
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Viral Load
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West Nile Fever
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West Nile Fever
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West Nile virus
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West Nile virus
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West Nile Virus Vaccines
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West Nile Virus Vaccines