"Macrophage Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.
| Descriptor ID |
D008262
|
| MeSH Number(s) |
G12.287.500
|
| Concept/Terms |
Macrophage Activation- Macrophage Activation
- Activation, Macrophage
- Activations, Macrophage
- Macrophage Activations
|
Below are MeSH descriptors whose meaning is more general than "Macrophage Activation".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Activation".
This graph shows the total number of publications written about "Macrophage Activation" by people in this website by year, and whether "Macrophage Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 2 | 0 | 2 |
| 2012 | 3 | 0 | 3 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 4 | 4 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macrophage Activation" by people in Profiles.
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The intersection of COVID-19 and autoimmunity. J Clin Invest. 2021 12 15; 131(24).
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Inhibition of ?-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation. Adipocyte. 2020 12; 9(1):325-334.
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Enhanced RIPK3 kinase activity-dependent lytic cell death in M1 but not M2 macrophages. Mol Immunol. 2021 01; 129:86-93.
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Long non-coding RNA FENDRR regulates IFN?-induced M1 phenotype in macrophages. Sci Rep. 2020 08 13; 10(1):13672.
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DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization. Mol Cancer Ther. 2020 07; 19(7):1539-1549.
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Decursinol angelate ameliorates 12-O-tetradecanoyl phorbol-13-acetate (TPA) -induced NF-?B activation on mice ears by inhibiting exaggerated inflammatory cell infiltration, oxidative stress and pro-inflammatory cytokine production. Food Chem Toxicol. 2019 Oct; 132:110699.
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IFN-? immune priming of macrophages in vivo induces prolonged STAT1 binding and protection against Cryptococcus neoformans. PLoS Pathog. 2018 10; 14(10):e1007358.
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MK2 Regulates Macrophage Chemokine Activity and Recruitment to Promote Colon Tumor Growth. Front Immunol. 2018; 9:1857.
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Innate Immune Responses and Osteoarthritis. Curr Rheumatol Rep. 2017 Aug; 19(8):45.
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Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages. Oncotarget. 2016 May 03; 7(18):25683-97.