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Irreversible EGFR inhibitor EKB-569 targets low-LET ?-radiation-triggered rel orchestration and potentiates cell death in squamous cell carcinoma.
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Irreversible EGFR inhibitor EKB-569 targets low-LET ?-radiation-triggered rel orchestration and potentiates cell death in squamous cell carcinoma.
Irreversible EGFR inhibitor EKB-569 targets low-LET ?-radiation-triggered rel orchestration and potentiates cell death in squamous cell carcinoma. PLoS One. 2011; 6(12):e29705.
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PubMed
subject areas
Aminoquinolines
Aminoquinolines
Aniline Compounds
Aniline Compounds
Carcinoma, Squamous Cell
Carcinoma, Squamous Cell
Cell Death
Cell Death
Cell Line, Tumor
Cell Line, Tumor
DNA, Neoplasm
DNA, Neoplasm
ErbB Receptors
ErbB Receptors
Gamma Rays
Gamma Rays
Gene Expression Regulation, Neoplastic
Gene Expression Regulation, Neoplastic
Humans
Humans
I-kappa B Kinase
I-kappa B Kinase
Linear Energy Transfer
Linear Energy Transfer
Neoplasm Proteins
Neoplasm Proteins
NF-kappa B
NF-kappa B
Protein Kinase Inhibitors
Protein Kinase Inhibitors
Proto-Oncogene Proteins c-rel
Proto-Oncogene Proteins c-rel
Radiation-Sensitizing Agents
Radiation-Sensitizing Agents
Signal Transduction
Signal Transduction
Transcription, Genetic
Transcription, Genetic
Up-Regulation
Up-Regulation
authors with profiles
Natarajan Aravindan
Sheeja Aravindan