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Tubulin inhibitory activity of a novel colchicine-binding compounds based on a dinaphthospiropyranran scaffold.
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Tubulin inhibitory activity of a novel colchicine-binding compounds based on a dinaphthospiropyranran scaffold.
Tubulin inhibitory activity of a novel colchicine-binding compounds based on a dinaphthospiropyranran scaffold. Bioorg Med Chem. 2021 01 01; 29:115874.
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PubMed
subject areas
Antineoplastic Agents
Antineoplastic Agents
Benzopyrans
Benzopyrans
Cell Line, Tumor
Cell Line, Tumor
Cell Proliferation
Cell Proliferation
Cell Survival
Cell Survival
Colchicine
Colchicine
Dose-Response Relationship, Drug
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Drug Screening Assays, Antitumor
Humans
Humans
Indoles
Indoles
Molecular Docking Simulation
Molecular Docking Simulation
Molecular Structure
Molecular Structure
Nitro Compounds
Nitro Compounds
Structure-Activity Relationship
Structure-Activity Relationship
Tubulin
Tubulin
Tubulin Modulators
Tubulin Modulators
authors with profiles
Vibhudutta Awasthi
Venkateswararao Eeda