"F-Box Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that share the F-BOX MOTIF and are involved in protein-protein interactions. They play an important role in process of protein ubiquition by associating with a variety of substrates and then associating into SCF UBIQUITIN LIGASE complexes. They are held in the ubiquitin-ligase complex via binding to SKP DOMAIN PROTEINS.
| Descriptor ID |
D044783
|
| MeSH Number(s) |
D12.776.157.169
|
| Concept/Terms |
F-Box Proteins- F-Box Proteins
- F Box Proteins
- F-Box Domain Protein
- Domain Protein, F-Box
- F Box Domain Protein
- Protein, F-Box Domain
- F-Box Protein Family
- F Box Protein Family
- Protein Family, F-Box
|
Below are MeSH descriptors whose meaning is more general than "F-Box Proteins".
Below are MeSH descriptors whose meaning is more specific than "F-Box Proteins".
This graph shows the total number of publications written about "F-Box Proteins" by people in this website by year, and whether "F-Box Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "F-Box Proteins" by people in Profiles.
-
JMJD5 links CRY1 function and proteasomal degradation. PLoS Biol. 2018 11; 16(11):e2006145.
-
A Rare Variant (rs933717) at FBXO31-MAP1LC3B in Chinese Is Associated With Systemic Lupus Erythematosus. Arthritis Rheumatol. 2018 02; 70(2):287-297.
-
Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length. EMBO J. 2015 Oct 01; 34(19):2424-40.
-
Glycosylation of Skp1 affects its conformation and promotes binding to a model f-box protein. Biochemistry. 2014 Mar 18; 53(10):1657-69.
-
Genetic reevaluation of the role of F-box proteins in cyclin D1 degradation. Mol Cell Biol. 2012 Feb; 32(3):590-605.
-
Split-hand/split-foot malformation 3 (SHFM3) at 10q24, development of rapid diagnostic methods and gene expression from the region. Am J Med Genet A. 2006 Jul 01; 140(13):1384-95.