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Nidheesh Thadathil

TitleFellow,Postdoctoral Research
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentBiochemistry/Molecular Biology
AddressBRC 1372
975 NE 10th St
Oklahoma City OK 73104
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ohene-Marfo P, Nguyen HVM, Mohammed S, Thadathil N, Tran A, Nicklas EH, Wang D, Selvarani R, Farriester JW, Varshney R, Kinter M, Richardson A, Rudolph MC, Deepa SS. Non-Necroptotic Roles of MLKL in Diet-Induced Obesity, Liver Pathology, and Insulin Sensitivity: Insights from a High-Fat, High-Fructose, High-Cholesterol Diet Mouse Model. Int J Mol Sci. 2024 Feb 28; 25(5). PMID: 38474061; PMCID: PMC10931720.
      Citations:    Fields:    Translation:HumansAnimals
    2. Deepa SS, Thadathil N, Corral J, Mohammed S, Pham S, Rose H, Kinter MT, Richardson A, D?az-Garc?a CM. MLKL overexpression leads to Ca2+ and metabolic dyshomeostasis in a neuronal cell model. Cell Calcium. 2024 May; 119:102854. PMID: 38430790; PMCID: PMC10990772.
      Citations:    Fields:    Translation:AnimalsCells
    3. Ohene-Marfo P, Nguyen HVM, Mohammed S, Thadathil N, Tran A, Nicklas EH, Wang D, Selvarani R, Farriester J, Varshney R, Kinter M, Richardson A, Rudolph M, Deepa SS. Non-Necroptotic Roles of MLKL in Diet-Induced Obesity, Liver Pathology, and Insulin Sensitivity: Insights from a High Fat, High Fructose, High Cholesterol Diet Mouse Model. bioRxiv. 2024 Jan 11. PMID: 38260537; PMCID: PMC10802562.
      Citations:    
    4. Kotey SK, Tan X, Fleming O, Kasiraju RR, Dagnell AL, Van Pelt KN, Rogers J, Hartson SD, Thadathil N, Selvarani R, Ranjit R, Logan S, Deepa SS, Richardson A, Cheng Y. Intracellular iron accumulation facilitates mycobacterial infection in old mouse macrophages. Geroscience. 2024 Apr; 46(2):2739-2754. PMID: 38159133.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Selvarani R, Van Michelle Nguyen H, Thadathil N, Wolf RF, Freeman WM, Wiley CD, Deepa SS, Richardson A. Characterization of novel mouse models to study the role of necroptosis in aging and age-related diseases. Geroscience. 2023 Oct 04. PMID: 37792157.
      Citations: 1     Fields:    Translation:Animals
    6. Mohammed S, Thadathil N, Ohene-Marfo P, Tran AL, Van Der Veldt M, Georgescu C, Oh S, Nicklas EH, Wang D, Haritha NH, Luo W, Janknecht R, Miller BF, Wren JD, Freeman WM, Deepa SS. Absence of either Ripk3 or Mlkl reduces incidence of hepatocellular carcinoma independent of liver fibrosis. Mol Cancer Res. 2023 May 19. PMID: 37204757.
      Citations: 6     Fields:    Translation:Animals
    7. Bhaskaran S, Kumar G, Thadathil N, Piekarz KM, Mohammed S, Lopez SD, Qaisar R, Walton D, Brown JL, Murphy A, Smith N, Saunders D, Beckstead MJ, Plafker S, Lewis TL, Towner R, Deepa SS, Richardson A, Axtell RC, Van Remmen H. Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis. Redox Biol. 2023 02; 59:102550. PMID: 36470129; PMCID: PMC9720104.
      Citations: 10     Fields:    Translation:AnimalsCells
    8. Thadathil N, Selvarani R, Mohammed S, Nicklas EH, Tran AL, Kamal M, Luo W, Brown JL, Lawrence MM, Borowik AK, Miller BF, Van Remmen H, Richardson A, Deepa SS. Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma. Aging Cell. 2022 Aug; 21(8):e13676. PMID: 35869934.
      Citations: 17     Fields:    Translation:Animals
    9. Mohammed S, Thadathil N, Selvarani R, Nicklas EH, Wang D, Miller BF, Richardson A, Deepa SS. Necroptosis contributes to chronic inflammation and fibrosis in aging liver. Aging Cell. 2021 12; 20(12):e13512. PMID: 34761505.
      Citations: 50     Fields:    
    10. Thadathil N, Nicklas EH, Mohammed S, Lewis TL, Richardson A, Deepa SS. Necroptosis increases with age in the brain and contributes to age-related neuroinflammation. Geroscience. 2021 10; 43(5):2345-2361. PMID: 34515928.
      Citations: 23     Fields:    Translation:Animals
    11. Mohammed S, Nicklas EH, Thadathil N, Selvarani R, Royce GH, Kinter M, Richardson A, Deepa SS. Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress. Free Radic Biol Med. 2021 02 20; 164:315-328. PMID: 33429022.
      Citations: 40     Fields:    Translation:Animals
    12. Thadathil N, Xiao J, Hori R, Alway SE, Khan MM. Brain Selective Estrogen Treatment Protects Dopaminergic Neurons and Preserves Behavioral Function in MPTP-induced Mouse Model of Parkinson's Disease. J Neuroimmune Pharmacol. 2021 09; 16(3):667-678. PMID: 33221984.
      Citations: 10     Fields:    Translation:AnimalsCells
    13. Thadathil N, Delotterie DF, Xiao J, Hori R, McDonald MP, Khan MM. DNA Double-Strand Break Accumulation in Alzheimer's Disease: Evidence from Experimental Models and Postmortem Human Brains. Mol Neurobiol. 2021 Jan; 58(1):118-131. PMID: 32895786.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    14. Thadathil N, Hori R, Xiao J, Khan MM. DNA double-strand breaks: a potential therapeutic target for neurodegenerative diseases. Chromosome Res. 2019 12; 27(4):345-364. PMID: 31707536.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    15. Salim C, Thadathil N, Muralidhara M, Rajini PS. Insights on the age dependent neurodegeneration induced by Monocrotophos, (an organophosphorous insecticide) in Caenorhabditis elegans fed high glucose: Evidence in wild and transgenic strains. Comp Biochem Physiol C Toxicol Pharmacol. 2018 Sep; 211:15-24. PMID: 29763691.
      Citations: 1     Fields:    Translation:AnimalsCells
    16. Thadathil N, Velappan SP. Recent developments in chitosanase research and its biotechnological applications: a review. Food Chem. 2014 May 01; 150:392-9. PMID: 24360467.
      Citations: 59     Fields:    
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