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Jialing Lin

TitleProf
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentBiochemistry/Molecular Biology
AddressBMSB 935
940 Stanton L Young Blvd
Oklahoma City OK 73104
Phone405/271-2227 ext 61216
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    Collapse Research 
    Collapse research activities and funding
    R01GM062964     (LIN, JIALING)Apr 1, 2001 - Aug 31, 2016
    NIH
    Structure-Function of Bcl-2 Related Apoptosis Regulators in Membranes
    Role: Principal Investigator
    F32GM017828     (LIN, JIALING)Mar 14, 1996
    NIH
    MULTISPANNING PROTEIN INTEGRATION INTO THE ER ME
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lin J. A protein bridge to death between the ER and mitochondria. J Biol Chem. 2023 Apr; 299(4):104581. PMID: 36871757; PMCID: PMC10074188.
      Citations:    Fields:    Translation:Cells
    2. Zhang Z, Huang B, Zhang XC, Lin J. Cysteine-based crosslinking approach for characterization of oligomeric pore-forming proteins in the mitochondrial membranes. Methods Enzymol. 2021; 649:371-396. PMID: 33712193.
      Citations:    Fields:    Translation:Cells
    3. Lin J. Tightening a deadly pore former. Nat Chem Biol. 2019 04; 15(4):316-317. PMID: 30778203.
      Citations:    Fields:    
    4. Lin J, Johnson AE, Zhang Z. Photocrosslinking Approach to Investigate Protein Interactions in the BCL-2 Family. Methods Mol Biol. 2019; 1877:131-149. PMID: 30536003.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    5. Zhang Z, Subramaniam S, Kale J, Liao C, Huang B, Brahmbhatt H, Condon SG, Lapolla SM, Hays FA, Ding J, He F, Zhang XC, Li J, Senes A, Andrews DW, Lin J. BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes. EMBO J. 2016 Jan 18; 35(2):208-36. PMID: 26702098.
      Citations: 53     Fields:    Translation:AnimalsCells
    6. Ding J, Mooers BHM, Zhang Z, Kale J, Falcone D, McNichol J, Huang B, Zhang XC, Xing C, Andrews DW, Lin J. After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial permeabilization. J Biol Chem. 2014 Apr 25; 289(17):11873-11896. PMID: 24616095.
      Citations: 41     Fields:    Translation:Cells
    7. Medina AP, Lin J, Weigel PH. Hyaluronan synthase mediates dye translocation across liposomal membranes. BMC Biochem. 2012 Jan 25; 13:2. PMID: 22276637.
      Citations: 7     Fields:    Translation:Cells
    8. Ding J, Zhang Z, Roberts GJ, Falcone M, Miao Y, Shao Y, Zhang XC, Andrews DW, Lin J. Bcl-2 and Bax interact via the BH1-3 groove-BH3 motif interface and a novel interface involving the BH4 motif. J Biol Chem. 2010 Sep 10; 285(37):28749-63. PMID: 20584903.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    9. Zhang Z, Zhu W, Lapolla SM, Miao Y, Shao Y, Falcone M, Boreham D, McFarlane N, Ding J, Johnson AE, Zhang XC, Andrews DW, Lin J. Bax forms an oligomer via separate, yet interdependent, surfaces. J Biol Chem. 2010 Jun 04; 285(23):17614-27. PMID: 20382739.
      Citations: 46     Fields:    Translation:HumansCells
    10. Peng J, Ding J, Tan C, Baggenstoss B, Zhang Z, Lapolla SM, Lin J. Oligomerization of membrane-bound Bcl-2 is involved in its pore formation induced by tBid. Apoptosis. 2009 Oct; 14(10):1145-53. PMID: 19701793.
      Citations: 17     Fields:    Translation:Cells
    11. Peng J, Lapolla SM, Zhang Z, Lin J. The Bax BH3 peptide H2-H3 promotes apoptosis by inhibiting Bcl-2's pore-forming and anti-Bax activities in the membrane. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Aug; 26(4):829-35. PMID: 19813621.
      Citations: 2     Fields:    Translation:HumansCells
    12. Peng J, Lapolla SM, Zhang Z, Lin J. The cytosolic domain of Bcl-2 oligomerizes to form pores in model mitochondrial outer membrane at acidic pH. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Jun; 26(3):631-7. PMID: 19634687.
      Citations: 1     Fields:    Translation:HumansCells
    13. Peng J, Lapolla SM, Zhang Z, Lin J. The cytosolic domain of Bcl-2 forms small pores in model mitochondrial outer membrane after acidic pH-induced membrane association. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Feb; 26(1):130-7. PMID: 19334571.
      Citations: 3     Fields:    Translation:HumansCells
    14. Peng J, Tan C, Roberts GJ, Nikolaeva O, Zhang Z, Lapolla SM, Primorac S, Andrews DW, Lin J. tBid elicits a conformational alteration in membrane-bound Bcl-2 such that it inhibits Bax pore formation. J Biol Chem. 2006 Nov 24; 281(47):35802-11. PMID: 17005564.
      Citations: 28     Fields:    Translation:AnimalsCells
    15. Tan C, Dlugosz PJ, Peng J, Zhang Z, Lapolla SM, Plafker SM, Andrews DW, Lin J. Auto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2. J Biol Chem. 2006 May 26; 281(21):14764-75. PMID: 16571718.
      Citations: 72     Fields:    Translation:AnimalsCells
    16. Zhang Z, Lapolla SM, Annis MG, Truscott M, Roberts GJ, Miao Y, Shao Y, Tan C, Peng J, Johnson AE, Zhang XC, Andrews DW, Lin J. Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax. J Biol Chem. 2004 Oct 15; 279(42):43920-8. PMID: 15302859.
      Citations: 32     Fields:    Translation:HumansCells
    17. Lin J, Liang Z, Zhang Z, Li G. Membrane topography and topogenesis of prenylated Rab acceptor (PRA1). J Biol Chem. 2001 Nov 09; 276(45):41733-41. PMID: 11535589.
      Citations: 12     Fields:    Translation:AnimalsCells
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