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Development of highly selective casein kinase 1d/1e (CK1d/e) inhibitors with potent antiproliferative properties.
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Development of highly selective casein kinase 1d/1e (CK1d/e) inhibitors with potent antiproliferative properties.
Development of highly selective casein kinase 1d/1e (CK1d/e) inhibitors with potent antiproliferative properties. Bioorg Med Chem Lett. 2013 Aug 01; 23(15):4374-80.
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PubMed
subject areas
Animals
Animals
Antineoplastic Agents
Antineoplastic Agents
Binding Sites
Binding Sites
Casein Kinase Idelta
Casein Kinase Idelta
Catalytic Domain
Catalytic Domain
Cell Line, Tumor
Cell Line, Tumor
Cell Survival
Cell Survival
Half-Life
Half-Life
Humans
Humans
Mice
Mice
Microsomes, Liver
Microsomes, Liver
Molecular Docking Simulation
Molecular Docking Simulation
Neoplasms
Neoplasms
Purines
Purines
Rats
Rats
Structure-Activity Relationship
Structure-Activity Relationship
Transplantation, Heterologous
Transplantation, Heterologous
authors with profiles
Ronald J Rahaim