"Lyme Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.
| Descriptor ID |
D008193
|
| MeSH Number(s) |
C01.252.400.155.569 C01.252.400.825.480 C01.252.847.193.569
|
| Concept/Terms |
Lyme Disease- Lyme Disease
- Disease, Lyme
- B. burgdorferi Infection
- B. burgdorferi Infections
- Lyme Borreliosis
- Borreliosis, Lyme
- Borrelia burgdorferi Infection
- Borrelia burgdorferi Infections
|
Below are MeSH descriptors whose meaning is more general than "Lyme Disease".
Below are MeSH descriptors whose meaning is more specific than "Lyme Disease".
This graph shows the total number of publications written about "Lyme Disease" by people in this website by year, and whether "Lyme Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 1 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Lyme Disease" by people in Profiles.
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Identification of a novel transport system in Borrelia burgdorferi that links the inner and outer membranes. Pathog Dis. 2023 01 17; 81.
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BB0562 is a nutritional virulence determinant with lipase activity important for Borrelia burgdorferi infection and survival in fatty acid deficient environments. PLoS Pathog. 2021 08; 17(8):e1009869.
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Borrelia peptidoglycan interacting Protein (BpiP) contributes to the fitness of Borrelia burgdorferi against host-derived factors and influences virulence in mouse models of Lyme disease. PLoS Pathog. 2021 04; 17(4):e1009535.
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A Novel Laminin-Binding Protein Mediates Microbial-Endothelial Cell Interactions and Facilitates Dissemination of Lyme Disease Pathogens. J Infect Dis. 2020 04 07; 221(9):1438-1447.
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Co-immunoprecipitation for Identifying Protein-Protein Interactions in Borrelia burgdorferi. Methods Mol Biol. 2018; 1690:47-55.
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Outer Membrane Proteins BB0405 and BB0406 Are Immunogenic, but Only BB0405 Is Required for Borrelia burgdorferi Infection. Infect Immun. 2017 02; 85(2).
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Consensus computational network analysis for identifying candidate outer membrane proteins from Borrelia spirochetes. BMC Microbiol. 2016 07 11; 16(1):141.
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Cyclic di-GMP modulates gene expression in Lyme disease spirochetes at the tick-mammal interface to promote spirochete survival during the blood meal and tick-to-mammal transmission. Infect Immun. 2015 Aug; 83(8):3043-60.
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The hybrid histidine kinase Hk1 is part of a two-component system that is essential for survival of Borrelia burgdorferi in feeding Ixodes scapularis ticks. Infect Immun. 2011 Aug; 79(8):3117-30.
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The OspE-related proteins inhibit complement deposition and enhance serum resistance of Borrelia burgdorferi, the lyme disease spirochete. Infect Immun. 2011 Apr; 79(4):1451-7.