Pentose Phosphate Pathway
"Pentose Phosphate Pathway" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An oxidative decarboxylation process that converts GLUCOSE-6-PHOSPHATE to D-ribose-5-phosphate via 6-phosphogluconate. The pentose product is used in the biosynthesis of NUCLEIC ACIDS. The generated energy is stored in the form of NADPH. This pathway is prominent in tissues which are active in the synthesis of FATTY ACIDS and STEROIDS.
| Descriptor ID |
D010427
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| MeSH Number(s) |
G02.111.158.875 G03.191.875 G03.295.693 G03.493.695
|
| Concept/Terms |
Pentose Phosphate Pathway- Pentose Phosphate Pathway
- Pathway, Pentose Phosphate
- Pathways, Pentose Phosphate
- Pentose Phosphate Pathways
- Pentose Phosphate Shunt
- Pentose Phosphate Shunts
- Shunt, Pentose Phosphate
- Shunts, Pentose Phosphate
- Pentose Shunt
- Pentose Shunts
- Shunt, Pentose
- Shunts, Pentose
- Pentose-Phosphate Pathway
- Pathway, Pentose-Phosphate
- Pathways, Pentose-Phosphate
- Pentose-Phosphate Pathways
- Pentosephosphate Shunt
- Pentosephosphate Shunts
- Shunt, Pentosephosphate
- Shunts, Pentosephosphate
- Hexose Monophosphate Shunt
- Hexose Monophosphate Shunts
- Shunt, Hexose Monophosphate
- Shunts, Hexose Monophosphate
- Pentosephosphate Pathway
- Pathway, Pentosephosphate
- Pathways, Pentosephosphate
- Pentosephosphate Pathways
|
Below are MeSH descriptors whose meaning is more general than "Pentose Phosphate Pathway".
Below are MeSH descriptors whose meaning is more specific than "Pentose Phosphate Pathway".
This graph shows the total number of publications written about "Pentose Phosphate Pathway" by people in this website by year, and whether "Pentose Phosphate Pathway" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2014 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pentose Phosphate Pathway" by people in Profiles.
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MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer. Cancer Cell. 2017 07 10; 32(1):71-87.e7.
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Beneficial effects of acute inhibition of the oxidative pentose phosphate pathway in the failing heart. Am J Physiol Heart Circ Physiol. 2014 Mar 01; 306(5):H709-17.
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MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13787-92.
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Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma. PLoS One. 2012; 7(3):e32996.
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Prolactin-mediated regulation of lipid biosynthesis genes in vivo in the lactating mammary epithelial cell. Am J Physiol Endocrinol Metab. 2011 Jun; 300(6):E1059-68.
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Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver. Free Radic Biol Med. 2009 Aug 01; 47(3):219-28.
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Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries. Am J Physiol Heart Circ Physiol. 2003 Dec; 285(6):H2316-26.
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Diminished pentose cycle flux in perfused livers of ethanol-fed rats. Mol Pharmacol. 1987 Jun; 31(6):631-7.