Tetradecanoylphorbol Acetate
"Tetradecanoylphorbol Acetate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.
Descriptor ID |
D013755
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MeSH Number(s) |
D02.455.849.291.500.510.850
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Concept/Terms |
Tetradecanoylphorbol Acetate- Tetradecanoylphorbol Acetate
- Acetate, Tetradecanoylphorbol
- 12-O-Tetradecanoyl Phorbol 13-Acetate
- 12 O Tetradecanoyl Phorbol 13 Acetate
- 13-Acetate, 12-O-Tetradecanoyl Phorbol
- Phorbol 13-Acetate, 12-O-Tetradecanoyl
- Phorbol Myristate Acetate
- Acetate, Phorbol Myristate
- Myristate Acetate, Phorbol
- 12-Myristoyl-13-acetylphorbol
- 12 Myristoyl 13 acetylphorbol
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Below are MeSH descriptors whose meaning is more general than "Tetradecanoylphorbol Acetate".
Below are MeSH descriptors whose meaning is more specific than "Tetradecanoylphorbol Acetate".
This graph shows the total number of publications written about "Tetradecanoylphorbol Acetate" by people in this website by year, and whether "Tetradecanoylphorbol Acetate" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 1 | 2 |
1997 | 0 | 1 | 1 |
1998 | 0 | 2 | 2 |
1999 | 1 | 2 | 3 |
2000 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2002 | 0 | 2 | 2 |
2006 | 0 | 2 | 2 |
2008 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tetradecanoylphorbol Acetate" by people in Profiles.
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Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1a-NF-?B Crosstalk In Vitro and In Vivo. Int J Mol Sci. 2020 Dec 04; 21(23).
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Bamboo leave extract ameliorated 12-O-tetradecanoylphorbol-13-acetate (TPA) induced ear inflammation by reducing MAP kinase levels and NF-?B activation in mice model. Nat Prod Res. 2021 Dec; 35(23):5299-5303.
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Decursinol angelate ameliorates 12-O-tetradecanoyl phorbol-13-acetate (TPA) -induced NF-?B activation on mice ears by inhibiting exaggerated inflammatory cell infiltration, oxidative stress and pro-inflammatory cytokine production. Food Chem Toxicol. 2019 Oct; 132:110699.
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Novel mechanism of impaired function of organic anion-transporting polypeptide 1B3 in human hepatocytes: post-translational regulation of OATP1B3 by protein kinase C activation. Drug Metab Dispos. 2014 Nov; 42(11):1964-70.
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Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity. Physiol Genomics. 2013 May 01; 45(9):351-66.
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Phorbol 12-myristate 13-acetate (PMA) responsive sequence in Galphaq promoter during megakaryocytic differentiation. Regulation by EGR-1 and MAP kinase pathway. Thromb Haemost. 2008 Nov; 100(5):821-8.
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Early growth response transcription factor EGR-1 regulates Galphaq gene in megakaryocytic cells. J Thromb Haemost. 2006 Dec; 4(12):2678-86.
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Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation. J Biol Chem. 2006 Mar 24; 281(12):7784-92.
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Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk. J Pharmacol Exp Ther. 2002 Aug; 302(2):502-9.
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A molecular basis for differential developmental anomalies in Axenfeld-Rieger syndrome. Hum Mol Genet. 2002 Apr 01; 11(7):743-53.