"Clarithromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
| Descriptor ID |
D017291
|
| MeSH Number(s) |
D02.540.576.500.992.100
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clarithromycin".
Below are MeSH descriptors whose meaning is more specific than "Clarithromycin".
This graph shows the total number of publications written about "Clarithromycin" by people in this website by year, and whether "Clarithromycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clarithromycin" by people in Profiles.
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Diagnostic and Treatment Practices for Helicobacter Pylori Infection in an Academic Pediatric Hospital. R I Med J (2013). 2023 Jul 05; 106(6):35-39.
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Mycobacterium chelonae Scleral Abscess After Intravitreal Ranibizumab Injection. Cornea. 2016 Aug; 35(8):1136-7.
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Clarithromycin in adult-onset still's disease: a potentially useful therapeutic. J Clin Rheumatol. 2011 Oct; 17(7):373-6.
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Effect of clarithromycin on cytokines and chemokines in children with an acute exacerbation of recurrent wheezing: a double-blind, randomized, placebo-controlled trial. Ann Allergy Asthma Immunol. 2006 Oct; 97(4):457-63.
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An economic and outcomes assessment of first-line monotherapy in the treatment of community-acquired pneumonia within managed care. Curr Med Res Opin. 2005 Feb; 21(2):261-70.
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Randomized, open-label trial of azithromycin plus ethambutol vs. clarithromycin plus ethambutol as therapy for Mycobacterium avium complex bacteremia in patients with human immunodeficiency virus infection. Veterans Affairs HIV Research Consortium. Clin Infect Dis. 1998 Nov; 27(5):1278-85.