"Erythromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
| Descriptor ID |
D004917
|
| MeSH Number(s) |
D02.540.576.500.992
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Erythromycin".
Below are MeSH descriptors whose meaning is more specific than "Erythromycin".
This graph shows the total number of publications written about "Erythromycin" by people in this website by year, and whether "Erythromycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Erythromycin" by people in Profiles.
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Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. J Med Chem. 2017 07 27; 60(14):6205-6219.
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Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane. Antimicrob Agents Chemother. 2016 12; 60(12):7372-7381.
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Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. Antimicrob Agents Chemother. 2010 Dec; 54(12):5366-8.
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An economic and outcomes assessment of first-line monotherapy in the treatment of community-acquired pneumonia within managed care. Curr Med Res Opin. 2005 Feb; 21(2):261-70.
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Efficacy of a motilin receptor agonist (ABT-229) for the treatment of gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2002 Apr; 16(4):749-57.
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Effects of localized Pasteurella haemolytica infection on erythromycin-binding properties of bovine alpha-1-acid glycoprotein, albumin, serum, and tissue chamber fluids. Antimicrob Agents Chemother. 1994 Oct; 38(10):2392-7.
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Transfer of pheromone-inducible plasmids between Enterococcus faecalis in the Syrian hamster gastrointestinal tract. J Infect Dis. 1992 Nov; 166(5):1188-91.
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A randomized placebo-controlled trial of erythromycin for the treatment of Ureaplasma urealyticum to prevent premature delivery. The Vaginal Infections and Prematurity Study Group. Am J Obstet Gynecol. 1991 Mar; 164(3):734-42.
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Chlamydial infections in pediatrics: diagnostic and therapeutic considerations. Pediatr Infect Dis. 1986 Jan-Feb; 5(1):158-62.
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Autogenous transduction of phi 11de in Staphylococcus aureus: transfer and genetic properties. J Bacteriol. 1984 May; 158(2):689-95.