"Codon, Nonsense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon.
| Descriptor ID |
D018389
|
| MeSH Number(s) |
D13.444.735.544.355.250.235 G05.360.335.355.250.235 G05.365.590.195
|
| Concept/Terms |
Codon, Nonsense- Codon, Nonsense
- Premature Termination Codon
- Codon, Premature Termination
- Codons, Premature Termination
- Premature Termination Codons
- Termination Codon, Premature
- Termination Codons, Premature
- Premature Stop Codon
- Codon, Premature Stop
- Codons, Premature Stop
- Premature Stop Codons
- Stop Codon, Premature
- Stop Codons, Premature
- Nonsense Codon
- Codons, Nonsense
- Nonsense Codons
- Codon, Termination, Premature
Mutation, Nonsense- Mutation, Nonsense
- Mutations, Nonsense
- Nonsense Mutations
- Nonsense Mutation
Ochre Nonsense Codon- Ochre Nonsense Codon
- Codon, Ochre Nonsense
- Codons, Ochre Nonsense
- Nonsense Codon, Ochre
- Nonsense Codons, Ochre
- Ochre Nonsense Codons
Ochre Nonsense Mutation- Ochre Nonsense Mutation
- Mutation, Ochre Nonsense
- Mutations, Ochre Nonsense
- Nonsense Mutation, Ochre
- Nonsense Mutations, Ochre
- Ochre Nonsense Mutations
Amber Nonsense Mutation- Amber Nonsense Mutation
- Amber Nonsense Mutations
- Mutation, Amber Nonsense
- Mutations, Amber Nonsense
- Nonsense Mutation, Amber
- Nonsense Mutations, Amber
Opal Nonsense Mutation- Opal Nonsense Mutation
- Mutation, Opal Nonsense
- Mutations, Opal Nonsense
- Nonsense Mutation, Opal
- Nonsense Mutations, Opal
- Opal Nonsense Mutations
Amber Nonsense Codon- Amber Nonsense Codon
- Amber Nonsense Codons
- Codon, Amber Nonsense
- Codons, Amber Nonsense
- Nonsense Codons, Amber
- Nonsense Codon, Amber
Codon, Unassigned- Codon, Unassigned
- Codons, Unassigned
- Unassigned Codons
- Unassigned Codon
Opal Nonsense Codon- Opal Nonsense Codon
- Codon, Opal Nonsense
- Codons, Opal Nonsense
- Nonsense Codon, Opal
- Nonsense Codons, Opal
- Opal Nonsense Codons
|
Below are MeSH descriptors whose meaning is more general than "Codon, Nonsense".
Below are MeSH descriptors whose meaning is more specific than "Codon, Nonsense".
This graph shows the total number of publications written about "Codon, Nonsense" by people in this website by year, and whether "Codon, Nonsense" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 2 | 3 |
| 2017 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Codon, Nonsense" by people in Profiles.
-
Severe growth failure associated with a novel heterozygous nonsense mutation in the GHR transmembrane domain leading to elevated growth hormone binding protein. Clin Endocrinol (Oxf). 2020 04; 92(4):331-337.
-
Reduced penetrance in a large Caucasian pedigree with Stickler syndrome. Ophthalmic Genet. 2017 Jan-Feb; 38(1):43-50.
-
Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma. J Natl Cancer Inst. 2015 Feb; 107(2).
-
A novel CaM kinase II pathway controls the location of neuropeptide release from Caenorhabditis elegans motor neurons. Genetics. 2014 Mar; 196(3):745-65.
-
Bilateral combined hamartomas of the retina and retinal pigment epithelium as the presenting feature of neurofibromatosis type 2 (Wishart Type). J Pediatr Ophthalmol Strabismus. 2014; 51 Online:doi: 10.3928/01913913-20140521-02.
-
Mutations in SCO2 are associated with autosomal-dominant high-grade myopia. Am J Hum Genet. 2013 May 02; 92(5):820-6.
-
Mutations in proteasome subunit ß type 8 cause chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature with evidence of genetic and phenotypic heterogeneity. Arthritis Rheum. 2012 Mar; 64(3):895-907.
-
Two new unrelated cases of hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from the same novel nonsense mutation in the vitamin D receptor gene. J Pediatr Endocrinol Metab. 2010 Aug; 23(8):843-50.
-
Autoimmunity as a result of escape from RNA surveillance. J Immunol. 2006 Aug 01; 177(3):1698-707.
-
A nonsense mutation of PEPD in four Amish children with prolidase deficiency. Am J Med Genet A. 2006 Mar 15; 140(6):580-5.